Probiotics and Allergy

Probiotics and Allergy
Presentation by:Shalini Jain , Hariom Yadav and PR Sinha

Animal Biochemistry Division
National Dairy Research Institute
Karnal,Haryana

Definition

Allergy is an adverse immune reaction to a molecule called allergen (protein) in our environment, which is normally harmless to the non-allergic person.

Types of Allergy

Classified according to symptoms they produce i.e. skin, nose and lungs etc and causes:

* Skin allergy
* Food allergy
* Allergen inhalation
* Allergy to medicine

Risk factors of Allergy

Allergen

An allergen - a substance causing allergic disease in sensitized host. These allergens enter into body by various means:

* Through the skin – cosmetics, stinging insects and oak
* Injections – drugs
* Oral ingestion – Eggs, prawns, peanuts, fish, cow’s milk
* Nose and lungs – airborne pollen of weeds, grasses, dust mite droppings

Symptoms of Allergy
Treatment
Probiotics
Probiotics in Treatment of disease

Probiotics have been found to act as alternative medicine for a number of diseases:
* Lactose intolerance
* Diarrhea
* Constipation
* Inflammatory bowel disease
* Respiratory disease
* Atherosclerosis
* Osteoporosis
* Allergy

Probiotics Role in Allergy
How probiotics work to prevent allergy

To treat allergy, probiotic acts in different ways:
* Degradation/structural modification of enteral antigens.
* Normalization of the properties of aberrant indigenous microbiota and of gut barrier functions.
* Regulation of the secretion of inflammatory mediators, and promoting development of the immune system.
* Prevents food allergy by promoting endogenous barrier mechanisms and alleviating intestinal inflammation.
* Stimulating immune response and reduction of serum IgE levels.
* Reduction of Th2 cytokine response.

Intestinal microflora
Future directions/ perspectives
Conclusion

Probiotics and Allergy.ppt