The Endocrine System

The Endocrine System

Normal Structure & Function

* Endocrine vs Exocrine glands
* Paracrine glands (diffuse endocrine)
* Autocrine effects
* Hormones
* Secondary messenger molecules (e.g. cAMP)
* Pituitary
* Adrenal Medulla
* Adrenal Cortex
* Thyroid
* Parathyroid
* Endocrine Pancreas

Endocrine Pathology
Pituitary
Hormone Secreting Cells of Adenohypophysis
Hypopituitarism
Pituitary Anenomas
Systemic Features of Acromegaly
Hormones of Neurohypophysis
Diabetes Insipidus
Syndrome of Inappropriate ADH Secretion
Adrenal Medulla
Pheochromocytoma
Adrenal Cortex
Steroid Hormones
Conditions Affecting Adrenal Cortex
Adrenocortical Hyperfunction
Cushing’s Syndrome
Hypercortisolism
Aetiology & Pathogenesis
Hyperaldosteronism
Primary Hyperaldosteronism
Seconday Hyperaldosteronism
Adrenogenital Syndromes
Acute Adrenocortical Insufficiency
Chronic Adrenocortical Insufficiency
Thyroid
Hyperthyroidism (Thyrotoxicosis)
Thyroid Storm
Hypothyroidism
Myxoedema
Cretinism
Myxoedema
Simple Goitre (Enlargement of the thyroid gland without hyperthyroidism)
Aetiology & Pathogenesis
Grave’s Disease
Thyroiditis inflammation of the thyroid
Non-specific Lymphocytic Thyroiditis
Hashimoto’s Thyroiditis -Chronic lymphocytic thyroiditis
Subacute (Granulomatous) Thyroiditis
Hashimoto’s Thyroiditis
Hypothyrodism
Neoplasms of Thyroid
Follicular Adenomas
Thyroid Carcinomas
Hyperparathyroidism
Primary Hyperparathyroidism
“Bones, Stones & Groans Disease”
Hypoparathyroidism
Endocrine Pancrease
Diabetes Mellitus
Insulin Dependant Diabetes Mellitus
Non-Insulin Dependant Diabetes Mellitus
Secondary Diabetes
Pathology of Insulin Deficiency
Complications
Large Blood Vessels
Small blood vessels
Peripheral Nervous System
Neutrophils
Pregnancy
Multiple Endocrine Neoplasia

The Endocrine System.ppt