03 May 2009

Focus on Headache



Focus on Headache

Headache

* Probably the most common type of pain experienced by humans
* Majority of people have functional headaches
o Migraine or tension-type headaches
* Not all cranium tissues are sensitive to pain
* Pain-sensitive structures include venous sinuses, dura, cranial blood vessels, divisions of the trigeminal nerve, facial nerve, glossopharyngeal nerve, vagus nerve, and the first three cervical nerves
* Classification from the International Headache Society diagnostic criteria
* Primary classifications
o Tension-type
o Migraine
o Cluster


Tension-Type Headache

* Most common type
* Bilateral, band-like feeling of pressure around the head
* Constant, squeezing tightness
* Not aggravated by physical activity
* Usually mild or moderate
* Often subcategorized into
o Infrequent episodic
o Frequent episodic
o Chronic

Tension-Type Headache Etiology and Pathophysiology

* Mechanism in all patients with tension-type headaches has neurovascular factors similar to those involved in migraine headaches

Tension-Type Headache Clinical Manifestations
* No nausea or vomiting
* May involve sensitivity to light and sound
* May occur intermittently
* Can have combination of migraine and tension-type headaches
* Careful history taking
* Electromyography may be performed
o May reveal sustained contraction of neck, scalp, or facial muscles
o May not show increased tension even when test is done during headache

Tension-Type Headache Diagnostic Studies

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Nutrition



Nutrition
Presentation lecture by:Amy C. Chavarria, RN, MSN, MBA, HCM, CCE

Dr.Chavarria described every vitamin / mineral in detail such as functions, sources, deficienties etc.
Essential Nutrients and Sources

* Water
* Carbohydrates
* Protein
* Fats
* Micronutrients
o Vitamins
o Minerals
Carbohydrates
Digestion, Absorption, and Metabolism: Carbohydrates

* Major enzymes include ptyalin (salivary amylase), pancreatic amylase, and the disaccharidases
* End products are monosaccharides
* Absorbed by the small intestine in healthy people
* Body breaks carbohydrates into glucose
o Maintain blood levels
o Provide a readily available source of energy

Proteins
Digestion, Absorption, and Metabolism: Protein

* Digestion begins in the mouth with enzyme pepsin
* Most protein digested in the small intestine
* Pancreas secretes the proteolytic enzymes trypsin, chymotrypsin, and carboxypeptidase
* Glands in intestinal wall secrete aminopeptidase and dipeptidase which break protein into amino acids
* Amino acids absorbed by active transport through small intestines
* Anabolism, catabolism, nitrogen balance

Lipids/Fats
Digestion, Absorption, and Metabolism: Lipids/Fats

* Digestion begins in the stomach, but mainly digested in the small intestine
* Digestion primarily by bile, pancreatic lipase, and enteric lipase
* End products of lipid digestion are glycerol, fatty acids, and cholesterol
* Reassembled inside the intestinal cells into triglycerides and cholesterol esters
Digestion, Absorption, and Metabolism: Lipids/Fats

* Small intestine and the liver convert these into soluble compounds called lipoprotein
* Converting fat into useable energy occurs through lipase that breaks down triglycerides in adipose cells releasing glycerol and fatty acids into the blood

Micronutrients
* Vitamins
* Minerals

VITAMIN A

FUNCTIONS: -maintenance of normal vision especially in dim light

* maintenance of healthy epithelium
* promotion of normal skeletal and teeth development
* promotion of cellular proliferation

SOURCES: liver, fish, liver oils, fortified milk and dairy products

DEFICIENCY/IES: Night blindness, Cessation of bone growth, Decreased mucous secretion of stomach and intestine, Dry eyes, scaly skin

VITAMIN D

FUNCTIONS: - intestinal absorption of calcium

* mobilization of calcium and phosphorus from bone
* renal absorption of calcium

SOURCES: exposure to sunlight

DEFICIENCY/CIES:
Rickets
Osteomalacia
Tetany

VITAMIN E FUNCTIONS: - antioxidant

* assists in maintaining the integrity of cellular membranes and protecting vitamin A from oxidation
SOURCES: vegetable oils, wheat germ, leafy vegetables, soybeans, corn, peanuts, margarine
DEFICIENCY/CIES: Rare-increase hemolysis of RBC
* poor reflexes

VITAMIN K

* Intake of this vitamin is needed in the liver for the formation of prothrombin & other clotting factors ----- ‘blood coagulation’

SOURCES: green leafy vegetables, cheese, egg yolk, liver
DEFICIENCY/CIES: Hemorrhage, Hemorrhagic Disease of the Newborn


VITAMIN B1 (THIAMINE)

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Bioterrorism



Bioterrorism
Presentation lecture by:Amy C. Chavarria, RN, MSN, MBA, HCM, CCE

The Face of Bioterrorism
BIOTERRORISM
HISTORY OF BIOLOGICAL WARFARE

* 18th Century: Smallpox Blankets
* 20th Century:
o 1943: USA program launched
o 1953: Defensive program established
o 1969: Offensive program disbanded

BIOLOGICAL WARFARE AGREEMENTS

* 1925 Geneva Protocol
* 1972 Biological Weapons Convention
* 1975 Geneva Conventions Ratified

Bioterrorism: Who are 1st Responders?

* Primary Care Personnel
* Hospital ER Staff
* EMS Personnel
* Public Health Professionals
* Other Emergency Preparedness Personnel
* Laboratory Personnel
* Law Enforcement
* Firefighters

PUBLIC HEALTH

ISSUES

* Existing local, regional, and national surveillance systems
o Adequate to detect traditional agents
o Inadequate to detect potential biowarfare agents
* Specific training for health care professionals
o clinical personnel will be “first responders”
* Civilian biodefense plans are usually based on HAZMAT models
o Assumes responders enter a high exposure environment near the source
o Assumes site of exposure is separate from the health care facility
o Assumes no time pressure for decontamination
o Maximum protection is provided for a minimum number of workers / rescuers
* HAZMAT
o OSHA mandates use of PPE based on site hazard, but site hazards are more easily defined at the point of release
o Traditional HAZMAT products are expensive, take time to set up, and are inadequate for large numbers of patients
o Difficult to train and maintain proficiency in a civilian work force with high turnover

Key Problems

* Managing an outbreak
o The hard problem
* Investigating the attack if it is bioterrorism
o Does not require any special laws
o Demands effective public health infrastructure
* Preventing bioterrorism
o Laws on control of agents and personnel

Minimal Threat

* Limited and non-communicable
o Anthrax Letters
* Scary, but very small risk to a small number of people
* Gross Overreaction in Government Office Buildings
* Huge Costs dealing with copycats
* No special legal problems

Significant Threat, Not Destabilizing
* Broad and non-communicable
o Anthrax from a crop duster over a major city
* Could be managed with massive, immediate antibiotic administration and management of causalities
* Panic will quickly become the core problem

Significant Threat, Potentially Destabilizing
* Limited and communicable
o A few cases of smallpox in one place
* Demands fast action
* If it spreads it can undermine public order
* Probably controllable, but with significant vaccine related causalities

Imminent Threat of Governmental Destabilization

* Broad and communicable
o Multiple cases of smallpox, multiple locations
* Would demand complete shutdown on transportation
* Would quickly require military intervention
* Local vaccination plans are mostly unworkable

POTENTIAL BIOTERRORISM AGENTS

* Bacterial Agents
o Anthrax
o Brucellosis
o Cholera
o Plague, Pneumonic
o Tularemia
o Q Fever
Source: U.S. A.M.R.I.I.D.
* Viruses
o Smallpox
o VEE
o VHF-viral hemorrhagic fever
* Biological Toxins
o Botulinum
o Staph Entero-B
o Ricin
o T-2 Mycotoxins

CRITICAL BIOLOGICAL AGENTS
CATEGORY A

* High priority agents that pose a threat to national security because they:
o can be easily disseminated or transmitted person-to-person
o cause high mortality, with potential for major public health impact
o might cause panic and social disruption
o require special public health preparedness
* Variola major (smallpox)
* Bacillus anthracis (anthrax)
* Yersinia pestis (plague)
* Clostridium botulinum toxin (botulism)
* Francisella tularensis (tularemia)
* Filoviruses
o Ebola hemorrhagic fever
o Marburg hemorrhagic fever
* Arenaviruses
o Lassa (Lassa fever)
o Junin (Argentine hemorrhagic fever) and related viruses

CRITICAL BIOLOGICAL AGENTS CATEGORY B

* Second highest priority agents that include those that:
o are moderately easy to disseminate
o cause moderate morbidity and low mortality
o require specific enhancements of CDC’s diagnostic capacity and enhanced disease surveillance
* Coxiella burnetti (Q fever)
* Brucella species (brucellosis)
* Burkholderia mallei (glanders)
* Alphaviruses
o Venezuelan encephalomyelitis
o eastern / western equine encephalomyelitis
* Ricin toxin from Ricinus communis (castor bean)
* Epsilon toxin of Clostridium perfringens
* Staphylococcus enterotoxin B
* Subset of Category B agents that include pathogens that are food- or waterborne
* Salmonella species
* Shigella dysenteriae

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