Institutional Animal Care and Use Committee Guidelines

Institutional Animal Care and Use Committee Guidelines of University of Minnesota

Hope this information will be useful to all researchers who deal with laboratory animals and members of Institutional Ethical Committee.

ANIMAL USE GUIDELINES & EXPECTATIONS Administration of Biological Materials to Rodents Amendment or Note to File Anesthesia, Surgery and Post-Procedural Recordkeeping (sample forms at bottom of page) Anesthetics, Analgesics and Tranquilizers in Lab Animals Availability of IACUC Protocols Avertin® (2,2,2 Tribromoethanol) Blood Collection Calibration - Output Validation of Anesthetic Machine Vaporizers Cage Space Guidelines Disaster/Emergency Planning Disaster/Emergency Plan Template for Animal Housing Sites Drug Formulary from RAR  Egg and Oocyte Harvesting in Xenopus laevis  Environmental Enrichment Euthanasia Criteria for Animals Used in Research, Teaching & Display Euthanasia Standard Methods and CO2 instructions Euthanasia for Amphibians, Reptiles, and Fish Food and Fluid Regulation  Housing and Husbandry Guidelines Humane Endpoints in Animal Care and Use Protocols Hypothermia as Anesthesia for Neonatal Rodents Identification of Animals outside of RAR Immunization, Adjuvants, Route of Administration Identification methods including Toe Clipping Investigator Managed Housing Area (IMHA) Oversight  Maintenance of Animals on an Expired IACUC Protocol Maintenance of Guillotines Multiple Surgical Procedures Needle Re-use Neuromuscular Blocking Agents in Animals Non-Pharmaceutical Grade Compounds in Research Perfusion as Euthanasia or as Non-survival surgery? Physical Restraint  Prevention, Assessment and Relief of Pain and Distress Restraint and Handling Rodent Survival Surgery Rodent Tail Biopsy Social Housing  Special Food or Fluid Provision Recordkeeping Surgery, Facility Requirements, Post-procedural Care, Antibiotics Transporting Animals Tumor Endpoint Criteria Use of Expired Drugs or Materials Wire Bar Flooring for Rodent Housing (scroll down to Rodents, Rabbits, Nonmammals)

Guidance from Professional Organizations Care and Use of Agriculutural Animals in Research and Teaching -  from the Federation of Animal Science Societies Guidelines For The Care And Use Of Mammals In Neuroscience And Behavioral Research -  from the National Research Council of the National Academies Use of Fishes - from the American Fisheries Society, American Institute of Fishery Research Biologists, and American Society of Ichthyologists and Herpetologists Use of Live Amphibians & Reptiles - from the American Society of Ichthyologists and Herpetologists, The Herpetologists' League, and Society for the Study of Amphibians and Reptiles Use of Wild Mammals - from the American Society of Mammalogists Use of Wild Birds - from the Ornithological Council Assessment and Management of Pain in Rodents and Rabbits - from the American College of Laboratory Animal Medicine Rodent Surgery - from the American College of Laboratory Animal Medicine    The 3 Rs (Reduction, Refinement, Replacement) - from the American College of Laboratory Animal Medicine

Federal and University Regulations U of M Board of Regents Policies Animal Care and Use Individual Conflict of Interest Institutional Conflict of Interest Principal Investigator Eligibility On Sponsored Projects Activities Involving Recombinant DNA or Other Potentially Hazardous Biological Agents Using Controlled Substances for Research Occupational and Environmental Health & Safety Links Office of Laboratory Animal Welfare (OLAW) Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training Guide for the Care and Use of Laboratory Animals Health Research Extension Act of 1985 U.S. Department of Agriculture (USDA) Animal Welfare Act Animal Care Policy Manual Other Policies AVMA Panel on Euthanasia

Sample Anesthesia, Surgery and Post-Procedural Recordkeeping Forms Mouse/Rat/Non-Mammal Post-Operative Record Mouse/Rat/Non-Mammal Procedure Form Mouse/Rat/Non-Mammal Procedure Record USDA Species Procedure Surgery Record USDA Species Anesthesia Monitoring Record USDA Species Post Procedure Recovery and Care Record