Bone morphogenetic proteins - BMP
Bone Morphogenetic Protein
By: Kim Stephens
http://www.ele.uri.edu
Bone Morphogenetic Protein Receptor 1A (BMPR1A) and Juvenile Polyposis Syndrome
Cara Davidson
http://courses.bio.unc.edu/
Bone Morphogenetic Proteins
Eric Niederhoffer
http://www.siumed.edu
Biological Treatment for Periodontal Regeneration
http://www.dent.ohio-state.
Demineralized bone matrix (DBM) is used in humans to induce bone formation
http://cbee.oregonstate.edu/
Periodontal Regenerative Surgery
Dr. E. Barrie Kenney
http://www.dent.ucla.edu/
Molecular Regulation Of Development Growth Factor Signaling,Hox Genes And The Body Plan
De Robertis
http://www.hhmi.ucla.edu/
Vascular Calcification
Kristina Boström, MD, PhD
http://www.mcdb.ucla.edu
Key Roles in Controlling Cell Proliferation and Synthesis of the Extracellular Matrix
http://web.mit.edu/
Structural Basis for Ligand-Receptor Recognition and Dimerization
Moosa Mohammadi
http://www.med.nyu.edu/
600 full text published articles free access
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2. Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata KI, Rikitake Y. Osteoblast-likedifferentiation of cultured human coronary artery smooth muscle Cells by bonemorphogenetic protein endothelial cell precursor-derived regulator (BMPER). JBiol Chem. 2012 Jul 9. [Epub ahead of print]
3. Ferreira E, Potier E, Vaudin P, Oudina K, Bensidhoum M, Logeart-Avramoglou D, Mir LM, Petite H. Sustained and promoter dependent bone morphogenetic proteinexpression by rat mesenchymal stem cells after BMP-2 transgene electrotransfer.Eur Cell Mater. 2012 Jul 9;24:18-28.
4. Saito H, Yamamura KI, Suzuki N. Facial dysmorphism induced by bonemorphogenetic protein receptor type 1A-mediated signaling reduction in neuralcrest-derived cells. Dis Model Mech. 2012 Jul 5. [Epub ahead of print]
5. Kawamura I, Maeda S, Imamura K, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S. SnoN suppresses maturation of chondrocytes by mediating signal crosstalk between transforming growth factor-β and bone morphogenetic protein pathways. J BiolChem. 2012 Jul 5. [Epub ahead of print]
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7. Sawala A, Sutcliffe C, Ashe HL. Multistep molecular mechanism for Bonemorphogenetic protein extracellular transport in the Drosophila embryo. Proc NatlAcad Sci U S A. 2012 Jul 10;109(28):11222-7. Epub 2012 Jun 25.
8. Callery EM, Park CY, Xu X, Zhu H, Smith JC, Thomsen GH. Eps15R is required forbone morphogenetic protein signalling and differentially compartmentalizes withSmad proteins. Open Biol. 2012 Apr;2(4):120060.
9. Wang D, Prakash J, Nguyen P, Davis-Dusenbery BN, Hill NS, Layne MD, Hata A,Lagna G. Bone Morphogenetic Protein signaling in vascular disease:anti-inflammatory action through Myocardin-related transcription factor A. J BiolChem. 2012 Jun 20. [Epub ahead of print]
10. Oumi N, Taniguchi KA, Kanai AM, Yasunaga M, Nakanishi T, Sato K. A crucialrole of bone morphogenetic protein signaling in the wound healing response inacute liver injury induced by carbon tetrachloride. Int J Hepatol.2012;2012:476820. Epub 2012 Jun 3.
11. Baltzer AW, Ostapczuk MS, Stosch D, Granrath M. The use of recombinant human bone morphogenetic protein-2 for the treatment of a delayed union followingfemoral neck open-wedge osteotomy. Orthop Rev (Pavia). 2012 Jan 2;4(1):e4. Epub2012 Mar 22.
12. Floerkemeier T, Witte F, Nellesen J, Thorey F, Windhagen H, Wellmann M.Repetitive recombinant human bone morphogenetic protein 2 injections improve the callus microarchitecture and mechanical stiffness in a sheep model of distractionosteogenesis. Orthop Rev (Pavia). 2012 Jan 2;4(1):e13. Epub 2012 Mar 9.
13. Tandon M, Gokul K, Ali SA, Chen Z, Lian J, Stein GS, Pratap J. Runx2 mediatesepigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells. Mol Cancer. 2012 Jun 18;11:27.
14. Washio A, Kitamura C, Morotomi T, Terashita M, Nishihara T. PossibleInvolvement of Smad Signaling Pathways in Induction of Odontoblastic Propertiesin KN-3 Cells by Bone Morphogenetic Protein-2. A Growth Factor to Induce DentinRegeneration. Int J Dent. 2012;2012:258469. Epub 2012 Feb 28.
15. Li G, Li Q, Lin LJ, Duan X, Zhang XQ. [Slow-release recombinant human bonemorphogenetic protein-2 suppresses chromium wear particle-induced osteolysis inrats]. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Mar;32(3):391-5. Chinese.
16. Wei JQ, Chen H, Zheng XF, Zhang BX, Wang Y, Tang PF, She F, Song Q, Li TS.[Hsa-miR-654-5p regulates osteogenic differentiation of human bone marrowmesenchymal stem cells by repressing bone morphogenetic protein 2]. Nan Fang YiKe Da Xue Xue Bao. 2012 Mar;32(3):291-5. Chinese.
17. Du L, Yang P, Zhao N, Ge S. [Culturing and characterization of humanperiodontal ligament stem cells and investigating their chemotactic responses to bone morphogenetic protein-2]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2012Feb;30(1):13-7. Chinese.
18. Angle SR, Sena K, Sumner DR, Virkus WW, Virdi AS. Healing of rat femoralsegmental defect with bone morphogenetic protein-2. a dose response study. JMusculoskelet Neuronal Interact. 2012 Mar;12(1):28-37.
19. Zhang J, Ge Y, Sun L, Cao J, Wu Q, Guo L, Wang Z. Effect of bonemorphogenetic protein-2 on proliferation and apoptosis of gastric cancer cells.Int J Med Sci. 2012;9(2):184-92. Epub 2012 Feb 15.
20. Li Y, Shen H, Burczynski FJ, Gong Y. Prospect of bone morphogenetic protein13 in liver diseases. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2012 Jan;37(1):1-5.
21. Wang J, Zhang J, Zhang Y, Ma NN, Xie LZ. [Prokaryotic expression ofrecombinant human bone morphogenetic protein-2 and preparation of monoclonalantibodies]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Oct;33(5):543-8. Chinese.
22. Yang HS, La WG, Cho YM, Shin W, Yeo GD, Kim BS. Comparison betweenheparin-conjugated fibrin and collagen sponge as bone morphogenetic protein-2carriers for bone regeneration. Exp Mol Med. 2012 May 31;44(5):350-5.
23. Fritsch C, Sawala A, Harris R, Maartens A, Sutcliffe C, Ashe HL, Ray RP.Different requirements for proteolytic processing of bone morphogenetic protein5/6/7/8 ligands in Drosophila melanogaster. J Biol Chem. 2012 Feb17;287(8):5942-53. Epub 2011 Dec 23.
24. Zheng YX, Wang J, Lin HT, Li L. Reconstruction of orbital defect in rabbitswith composite of calcium phosphate cement and recombinant human bonemorphogenetic protein-2. Chin Med J (Engl). 2010 Dec;123(24):3658-62.
25. Jiang J, Zhang J, Wang X, Xue L, Song H, Zhang X. [Effects of bonemorphogenetic protein-2 on proliferation of tongue cancer Tca8113]. Hua Xi KouQiang Yi Xue Za Zhi. 2011 Oct;29(5):546-9. Chinese.
26. Kim HJ, Nam HW, Hur CY, Park M, Yang HS, Kim BS, Park JH. The effect ofplatelet rich plasma from bone marrow aspirate with added bone morphogeneticprotein-2 on the Achilles tendon-bone junction in rabbits. Clin Orthop Surg. 2011Dec;3(4):325-31. Epub 2011 Dec 1.
27. Birke O, Schindeler A, Ramachandran M, Cowell CT, Munns CF, Bellemore M,Little DG. Preliminary experience with the combined use of recombinant bonemorphogenetic protein and bisphosphonates in the treatment of congenitalpseudarthrosis of the tibia. J Child Orthop. 2010 Dec;4(6):507-17. Epub 2010 Oct 21.
28. Li Z, Wang Y, Wang XN, Lan AP, Wu W. [Strontium ranelate promotes osteogenic differentiation of rat bone marrow mesenchymal stem cells by increasing bonemorphogenetic protein-7 expression]. Nan Fang Yi Ke Da Xue Xue Bao. 2011Nov;31(11):1949-53. Chinese.
29. Kobayashi A, Okuda H, Xing F, Pandey PR, Watabe M, Hirota S, Pai SK, Liu W,Fukuda K, Chambers C, Wilber A, Watabe K. Bone morphogenetic protein 7 indormancy and metastasis of prostate cancer stem-like cells in bone. J Exp Med.2011 Dec 19;208(13):2641-55. Epub 2011 Nov 28. Erratum in. J Exp Med. 2012 Mar12;209(3):639.
30. Han SH, Kim KH, Han JS, Koo KT, Kim TI, Seol YJ, Lee YM, Ku Y, Rhyu IC.Response of osteoblast-like cells cultured on zirconia to bone morphogeneticprotein-2. J Periodontal Implant Sci. 2011 Oct;41(5):227-33. Epub 2011 Oct 31.
31. Perron JC, Dodd J. Inductive specification and axonal orientation of spinalneurons mediated by divergent bone morphogenetic protein signaling pathways.Neural Dev. 2011 Nov 15;6:36.
32. Lee JW, Lee S, Lee SH, Yang HS, Im GI, Kim CS, Park JH, Kim BS. Improvedspinal fusion efficacy by long-term delivery of bone morphogenetic protein-2 in arabbit model. Acta Orthop. 2011 Dec;82(6):756-60. Epub 2011 Nov 9.
33. Heinke J, Kerber M, Rahner S, Mnich L, Lassmann S, Helbing T, Werner M,Patterson C, Bode C, Moser M. Bone morphogenetic protein modulator BMPER ishighly expressed in malignant tumors and controls invasive cell behavior.Oncogene. 2012 Jun 14;31(24):2919-30. doi. 10.1038/onc.2011.473. Epub 2011 Oct24.
34. Varanasi SS, Tuck SP, Mastana SS, Dennison E, Cooper C, Vila J, Francis RM,Datta HK. Lack of association of bone morphogenetic protein 2 gene haplotypeswith bone mineral density, bone loss, or risk of fractures in men. J Osteoporos. 2011;2011:243465. Epub 2011 Oct 13.
35. Wang H, Zhang LC, Shi T, Xiong Q, Tang PF. [Properties evaluation ofcollagen-hydroxyapatite-chondroitin sulfate-bone morphogenetic protein bonesubstitute material]. Beijing Da Xue Xue Bao. 2011 Oct 18;43(5):730-4. Chinese.
36. Dummula K, Vinukonda G, Chu P, Xing Y, Hu F, Mailk S, Csiszar A, Chua C,Mouton P, Kayton RJ, Brumberg JC, Bansal R, Ballabh P. Bone morphogenetic proteininhibition promotes neurological recovery after intraventricular hemorrhage. JNeurosci. 2011 Aug 24;31(34):12068-82.
37. Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L,Margraf L, Rakheja D, Amatruda JF. Mutation in the type IB bone morphogeneticprotein receptor Alk6b impairs germ-cell differentiation and causes germ-celltumors in zebrafish. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13153-8. Epub2011 Jul 20.
38. Li HF, Jiang XH, Zou DQ, Cao QL, Lü J, Li Y, Zhang HF, Wang YP. [Expressionof bone morphogenetic protein receptor IA in rats after contusive spinal cordinjury]. Nan Fang Yi Ke Da Xue Xue Bao. 2011 Jun;31(7):1124-30. Chinese.
39. Dong J, Zeng S, Ouyang M, Huang Z, Gong Y, Shen H. [Effect of bonemorphogenetic protein-4 on the proliferation and differentiation of rat hepaticprecursor cells]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011 Jun;36(6):539-45.Chinese.
40. Aoyama K, Yamane A, Suga T, Suzuki E, Fukui T, Nakamura Y. Bone morphogeneticprotein-2 functions as a negative regulator in the differentiation of myoblasts, but not as an inducer for the formations of cartilage and bone in mouse embryonictongue. BMC Dev Biol. 2011 Jul 7;11:44.
41. Hino J, Miyazawa T, Miyazato M, Kangawa K. Bone morphogenetic protein-3b(BMP-3b) is expressed in adipocytes and inhibits adipogenesis as a uniquecomplex. Int J Obes (Lond). 2012 May;36(5):725-34. doi. 10.1038/ijo.2011.124.Epub 2011 Jun 28.
42. Sethi A, Craig J, Bartol S, Chen W, Jacobson M, Coe C, Vaidya R. Radiographicand CT evaluation of recombinant human bone morphogenetic protein-2-assistedspinal interbody fusion. AJR Am J Roentgenol. 2011 Jul;197(1):W128-33. Erratumin. AJR Am J Roentgenol. 2011 Oct;197(4):1024. Jacobsen, Mark [corrected toJacobson, Mark].
43. Rakovac M, Bojanic I, Smoljanovic T. Recombinant human bone morphogeneticprotein 2 labeled use in spinal surgery and sexual dysfunction. Surg Neurol Int. 2011;2:55. Epub 2011 Apr 28.
44. Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C. Negative feedback inthe bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamicsignaling range and canalizes development. Proc Natl Acad Sci U S A. 2011 Jun21;108(25):10202-7. Epub 2011 Jun 1.
45. Chiang PM, Wong PC. Differentiation of an embryonic stem cell to hemogenicendothelium by defined factors. essential role of bone morphogenetic protein 4.Development. 2011 Jul;138(13):2833-43. Epub 2011 May 25.
46. Wu S, Morrison A, Sun H, De Luca F. Nuclear factor-kappaB (NF-kappaB) p65interacts with Stat5b in growth plate chondrocytes and mediates the effects ofgrowth hormone on chondrogenesis and on the expression of insulin-like growthfactor-1 and bone morphogenetic protein-2. J Biol Chem. 2011 Jul15;286(28):24726-34. Epub 2011 May 18.
47. Nakamura Y, Inloes JB, Katagiri T, Kobayashi T. Chondrocyte-specificmicroRNA-140 regulates endochondral bone development and targets Dnpep tomodulate bone morphogenetic protein signaling. Mol Cell Biol. 2011Jul;31(14):3019-28. Epub 2011 May 16.
48. Hamilton DK, Smith JS, Reames DL, Williams BJ, Shaffrey CI. Use ofrecombinant human bone morphogenetic protein-2 as an adjunct for instrumentedposterior arthrodesis in the occipital cervical region. An analysis of safety,efficacy, and dosing. J Craniovertebr Junction Spine. 2010 Jul;1(2):107-12.
49. Susan-Resiga D, Essalmani R, Hamelin J, Asselin MC, Benjannet S, Chamberland A, Day R, Szumska D, Constam D, Bhattacharya S, Prat A, Seidah NG. Furin is themajor processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10. J Biol Chem. 2011 Jul 1;286(26):22785-94. Epub 2011 May 5.
50. Xu X, Jha AK, Duncan RL, Jia X. Heparin-decorated, hyaluronic acid-basedhydrogel particles for the controlled release of bone morphogenetic protein 2.Acta Biomater. 2011 Aug;7(8):3050-9. Epub 2011 Apr 24.
51. Parikh P, Hao Y, Hosseinkhani M, Patil SB, Huntley GW, Tessier-Lavigne M, ZouH. Regeneration of axons in injured spinal cord by activation of bonemorphogenetic protein/Smad1 signaling pathway in adult neurons. Proc Natl AcadSci U S A. 2011 May 10;108(19):E99-107. Epub 2011 Apr 25.
52. Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL.Serum and liver iron differently regulate the bone morphogenetic protein 6(BMP6)-SMAD signaling pathway in mice. Hepatology. 2011 Jul;54(1):273-84. doi:10.1002/hep.24359.
53. Rey-Rico A, Silva M, Couceiro J, Concheiro A, Alvarez-Lorenzo C. Osteogenicefficiency of in situ gelling poloxamine systems with and without bonemorphogenetic protein-2. Eur Cell Mater. 2011 Apr 11;21:317-40.
54. Geng Y, Dong Y, Yu M, Zhang L, Yan X, Sun J, Qiao L, Geng H, Nakajima M,Furuichi T, Ikegawa S, Gao X, Chen YG, Jiang D, Ning W. Follistatin-like 1(Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist incontrolling mouse lung development. Proc Natl Acad Sci U S A. 2011 Apr26;108(17):7058-63. Epub 2011 Apr 11.
55. Crawford JL, Heath DA, Reader KL, Quirke LD, Hudson NL, Juengel JL, McNattyKP. Oocytes in sheep homozygous for a mutation in bone morphogenetic proteinreceptor 1B express lower mRNA levels of bone morphogenetic protein 15 but notgrowth differentiation factor 9. Reproduction. 2011 Jul;142(1):53-61. Epub 2011Apr 7.
56. Tominaga T, Abe H, Ueda O, Goto C, Nakahara K, Murakami T, Matsubara T, Mima A, Nagai K, Araoka T, Kishi S, Fukushima N, Jishage K, Doi T. Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimicsdiabetic nephropathy. J Biol Chem. 2011 Jun 3;286(22):20109-16. Epub 2011 Apr 6.
57. Marom B, Heining E, Knaus P, Henis YI. Formation of stable homomeric andtransient heteromeric bone morphogenetic protein (BMP) receptor complexesregulates Smad protein signaling. J Biol Chem. 2011 Jun 3;286(22):19287-96. Epub 2011 Apr 6.
58. Shimizu T, Tanaka T, Iso T, Matsui H, Ooyama Y, Kawai-Kowase K, Arai M,Kurabayashi M. Notch signaling pathway enhances bone morphogenetic protein 2(BMP2) responsiveness of Msx2 gene to induce osteogenic differentiation andmineralization of vascular smooth muscle cells. J Biol Chem. 2011 May27;286(21):19138-48. Epub 2011 Apr 6.
59. van Hout WM, Mink van der Molen AB, Breugem CC, Koole R, Van Cann EM.Reconstruction of the alveolar cleft. can growth factor-aided tissue engineering replace autologous bone grafting? A literature review and systematic review ofresults obtained with bone morphogenetic protein-2. Clin Oral Investig. 2011Jun;15(3):297-303. Epub 2011 Apr 5. Review.
60. Bhattacharyya T. Commentary on an article by Hannu T. Aro, MD, PhD, et al.:"Recombinant human bone morphogenetic protein-2. a randomized trial in opentibial fractures treated with reamed nail fixation". J Bone Joint Surg Am. 2011May 4;93(9):e50. Epub 2011 Mar 31. Erratum in. J Bone Joint Surg Am. 2011 May4;93(9):e50.
61. Dejima K, Kanai MI, Akiyama T, Levings DC, Nakato H. Novel contact-dependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfateproteoglycans. J Biol Chem. 2011 May 13;286(19):17103-11. Epub 2011 Mar 23.
62. Grgurevic L, Macek B, Healy DR, Brault AL, Erjavec I, Cipcic A, Grgurevic I, Rogic D, Galesic K, Brkljacic J, Stern-Padovan R, Paralkar VM, Vukicevic S.Circulating bone morphogenetic protein 1-3 isoform increases renal fibrosis. J AmSoc Nephrol. 2011 Apr;22(4):681-92. Epub 2011 Mar 17.
63. Xu J, Zhu D, He S, Spee C, Ryan SJ, Hinton DR. Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship withage-related macular degeneration. FASEB J. 2011 Jul;25(7):2221-33. Epub 2011 Mar 16.
64. Hosoe M, Kaneyama K, Ushizawa K, Hayashi KG, Takahashi T. Quantitativeanalysis of bone morphogenetic protein 15 (BMP15) and growth differentiationfactor 9 (GDF9) gene expression in calf and adult bovine ovaries. Reprod BiolEndocrinol. 2011 Mar 15;9:33.
65. Stottmann RW, Klingensmith J. Bone morphogenetic protein signaling isrequired in the dorsal neural folds before neurulation for the induction ofspinal neural crest cells and dorsal neurons. Dev Dyn. 2011 Apr;240(4):755-65.doi. 10.1002/dvdy.22579. Epub 2011 Mar 10.
66. Steinbicker AU, Sachidanandan C, Vonner AJ, Yusuf RZ, Deng DY, Lai CS,Rauwerdink KM, Winn JC, Saez B, Cook CM, Szekely BA, Roy CN, Seehra JS, Cuny GD, Scadden DT, Peterson RT, Bloch KD, Yu PB. Inhibition of bone morphogeneticprotein signaling attenuates anemia associated with inflammation. Blood. 2011 May5;117(18):4915-23. Epub 2011 Mar 10.
67. Klose A, Waerzeggers Y, Monfared P, Vukicevic S, Kaijzel EL, Winkeler A,Wickenhauser C, Löwik CW, Jacobs AH. Imaging bone morphogenetic protein 7 inducedcell cycle arrest in experimental gliomas. Neoplasia. 2011 Mar;13(3):276-85.
68. Anderson BC, Daniel ML, Kendall JD, Christiansen SP, McLoon LK. Sustainedrelease of bone morphogenetic protein-4 in adult rabbit extraocular muscleresults in decreased force and muscle size. potential for strabismus treatment.Invest Ophthalmol Vis Sci. 2011 Jun 8;52(7):4021-9. Print 2011 Jun.
69. Dendooven A, van Oostrom O, van der Giezen DM, Leeuwis JW, Snijckers C, JolesJA, Robertson EJ, Verhaar MC, Nguyen TQ, Goldschmeding R. Loss of endogenous bonemorphogenetic protein-6 aggravates renal fibrosis. Am J Pathol. 2011Mar;178(3):1069-79.
70. Kuroda S, Goto N, Suzuki M, Kaneda K, Ohya K, Shimokawa H, Kasugai S.Regeneration of bone- and tendon/ligament-like tissues induced by gene transferof bone morphogenetic protein-12 in a rat bone defect. J Tissue Eng. 2010 Apr15;2010:891049.
71. Du Y, Wang Y, Wang L, Liu B, Tian Q, Liu CJ, Zhang T, Xu Q, Zhu Y, Ake O, Qi Y, Tang C, Kong W, Wang X. Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.Circ Res. 2011 Apr 15;108(8):917-28. Epub 2011 Feb 24.
72. Pham L, Beyer K, Jensen ED, Rodriguez JS, Davydova J, Yamamoto M, Petryk A,Gopalakrishnan R, Mansky KC. Bone morphogenetic protein 2 signaling inosteoclasts is negatively regulated by the BMP antagonist, twisted gastrulation. J Cell Biochem. 2011 Mar;112(3):793-803. doi. 10.1002/jcb.23003.
73. Su X, Ao L, Shi Y, Johnson TR, Fullerton DA, Meng X. Oxidized low densitylipoprotein induces bone morphogenetic protein-2 in coronary artery endothelialcells via Toll-like receptors 2 and 4. J Biol Chem. 2011 Apr 8;286(14):12213-20. Epub 2011 Feb 16.
74. Schleinitz D, Klöting N, Böttcher Y, Wolf S, Dietrich K, Tönjes A, Breitfeld J, Enigk B, Halbritter J, Körner A, Schön MR, Jenkner J, Tseng YH, Lohmann T,Dressler M, Stumvoll M, Blüher M, Kovacs P. Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology ofobesity. PLoS One. 2011 Feb 2;6(2):e16155.
75. Dizon ML, Maa T, Kessler JA. The bone morphogenetic protein antagonist nogginprotects white matter after perinatal hypoxia-ischemia. Neurobiol Dis. 2011Jun;42(3):318-26. Epub 2011 Feb 17.
76. Zara JN, Siu RK, Zhang X, Shen J, Ngo R, Lee M, Li W, Chiang M, Chung J, KwakJ, Wu BM, Ting K, Soo C. High doses of bone morphogenetic protein 2 inducestructurally abnormal bone and inflammation in vivo. Tissue Eng Part A. 2011May;17(9-10):1389-99. Epub 2011 Mar 3.
77. Hisa I, Inoue Y, Hendy GN, Canaff L, Kitazawa R, Kitazawa S, Komori T,Sugimoto T, Seino S, Kaji H. Parathyroid hormone-responsive Smad3-related factor,Tmem119, promotes osteoblast differentiation and interacts with the bonemorphogenetic protein-Runx2 pathway. J Biol Chem. 2011 Mar 18;286(11):9787-96.Epub 2011 Jan 14.
78. Thorey F, Menzel H, Lorenz C, Gross G, Hoffmann A, Windhagen H.Osseointegration by bone morphogenetic protein-2 and transforming growth factorbeta2 coated titanium implants in femora of New Zealand white rabbits. Indian JOrthop. 2011 Jan;45(1):57-62.
79. Boström KI, Jumabay M, Matveyenko A, Nicholas SB, Yao Y. Activation ofvascular bone morphogenetic protein signaling in diabetes mellitus. Circ Res.2011 Feb 18;108(4):446-57. Epub 2010 Dec 30.
80. Son JW, Kim MK, Park YM, Baek KH, Yoo SJ, Song KH, Son HS, Yoon KH, Lee WC,Cha BY, Son HY, Kwon HS. Association of serum bone morphogenetic protein 4 levelswith obesity and metabolic syndrome in non-diabetic individuals. Endocr J.2011;58(1):39-46. Epub 2010 Dec 21.
81. Yu NY, Schindeler A, Peacock L, Mikulec K, Baldock PA, Ruys AJ, Little DG. Invivo local co-delivery of recombinant human bone morphogenetic protein-7 andpamidronate via poly-D, L-lactic acid. Eur Cell Mater. 2010 Dec 22;20:431-41;discussion 441-2.
82. Lai RF, Zhao QT, Liu XN, Shen S. [Study on osteogenic ability ofchitosan/beta-tricalcium phosphate scaffold combined with human bonemorphogenetic protein]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2010 Oct;28(5):464-7.Chinese.
83. Kangsamaksin T, Morris RJ. Bone morphogenetic protein 5 regulates the number of keratinocyte stem cells from the skin of mice. J Invest Dermatol. 2011Mar;131(3):580-5. Epub 2010 Dec 23.
84. Rui YF, DU L, Wang Y, Wang Y, Lui PP, Tang TT, Chan KM, Dai KR. Bonemorphogenetic protein 2 promotes transforming growth factor β3-inducedchondrogenesis of human osteoarthritic synovium-derived stem cells. Chin Med J(Engl). 2010 Nov;123(21):3040-8.
85. Seya K, Yu Z, Kanemaru K, Daitoku K, Akemoto Y, Shibuya H, Fukuda I, Okumura K, Motomura S, Furukawa K. Contribution of bone morphogenetic protein-2 to aorticvalve calcification in aged rat. J Pharmacol Sci. 2011;115(1):8-14. Epub 2010 Dec9.
86. Haubold M, Weise A, Stephan H, Dünker N. Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells. Int J Biol Sci. 2010 Nov 24;6(7):700-15.
87. Chan MC, Weisman AS, Kang H, Nguyen PH, Hickman T, Mecker SV, Hill NS, Lagna G, Hata A. The amiloride derivative phenamil attenuates pulmonary vascularremodeling by activating NFAT and the bone morphogenetic protein signalingpathway. Mol Cell Biol. 2011 Feb;31(3):517-30. Epub 2010 Dec 6.
88. Ozkan ZS, Deveci D, Onalan Etem E, Yüce H. Lack of effect of bonemorphogenetic protein 2 and 4 gene polymorphisms on bone density inpostmenopausal Turkish women. Genet Mol Res. 2010 Nov 30;9(4):2311-6.
89. Kato S, Sangadala S, Tomita K, Titus L, Boden SD. A synthetic compound thatpotentiates bone morphogenetic protein-2-induced transdifferentiation ofmyoblasts into the osteoblastic phenotype. Mol Cell Biochem. 2011Mar;349(1-2):97-106. Epub 2010 Nov 26.
90. Phan KD, Hazen VM, Frendo M, Jia Z, Butler SJ. The bone morphogenetic proteinroof plate chemorepellent regulates the rate of commissural axonal growth. JNeurosci. 2010 Nov 17;30(46):15430-40.
91. Chen XQ, Wu SH, Zhou XY. [Effects of antenatal administration ofdexamethasone and betamethasone on signal transduction of bone morphogeneticprotein in the fetal lungs of rats]. Zhongguo Dang Dai Er Ke Za Zhi. 2010Nov;12(11):891-6. Chinese.
92. Bramlage CP, Tampe B, Koziolek M, Maatouk I, Bevanda J, Bramlage P, Ahrens K,Lange K, Schmid H, Cohen CD, Kretzler M, Müller GA. Bone morphogenetic protein(BMP)-7 expression is decreased in human hypertensive nephrosclerosis. BMCNephrol. 2010 Nov 16;11:31.
93. Wahdan-Alaswad RS, Song K, Krebs TL, Shola DT, Gomez JA, Matsuyama S,Danielpour D. Insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling. Cancer Res. 2010Nov 15;70(22):9106-17. Epub 2010 Nov 9.
94. Ho SK, Peel SA, Hu ZM, Sándor GK, Clokie CM. Augmentation of the maxillarysinus. comparison of bioimplants containing bone morphogenetic protein andautogenous bone in a rabbit model. J Can Dent Assoc. 2010;76:a108.
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