23 February 2012

Blood test that tells you how long you'll live




The controversial test measures vital structures on the tips of a person's chromosomes, called telomeres, which scientists believe are one of the most important and accurate indicators of the speed at which a person is ageing.

Scientists behind the €500 (£435) test said it will be possible to tell whether a person's "biological age", as measured by the length of their telomeres, is older or younger than their actual chronological age.

Medical researchers believe that telomere testing will become widespread within the next five or 10 years, but there are already some scientists who question its value and whether there should be stronger ethical controls over its wider use. In addition to concerns about how people will react to a test for how "old" they really are, some scientists are worried that telomere testing may be hijacked by unscrupulous organisations trying to peddle unproven anti-ageing remedies and other fake elixirs of life.

The results of the tests might also be of interest to companies offering life-insurance policies or medical cover that depend on a person's lifetime risk of falling seriously ill or dying prematurely. However, there is a growing body of scientific opinion that says testing the length of a person's telomeres could provide vital insights into the risk of dying prematurely from a range of age-related disorders, from cardiovascular disease to Alzheimer's and cancer. "We know that people who are born with shorter telomeres than normal also have a shorter lifespan. We know that shorter telomeres can cause a shorter lifespan," said Maria Blasco of the Spanish National Cancer Research Centre in Madrid, who is the inventor of the new commercial telomere test. "But we don't know whether longer telomeres are going to give you a longer lifespan. That's not really known in humans," she added.

Telomeres: a short history
* 2003 Scientists studying 20-year-old blood samples from 143 people show that telomere length is good indicator of whether someone is likely to live for 15 years or more once they reach 60.

* 2004 Women living with stress of having a sick child are found to have shorter telomeres. Other research suggests that meditation or other forms of stress reduction may lengthen telomeres.

* 2007 Study of men in Scotland shows those with the longest telomeres were half as likely to develop heart disease than those with shorter telomeres. Telomere length was as good as cholesterol levels at predicting the risk of developing cardiovascular disease.

* 2009 Short telomeres linked with inherited bone marrow disease.

* 2010 GM mice with no telomerase, an enzyme that elongates telomeres in some cells, age prematurely compared to normal mice. The ageing effects were reversed after injections of telomerase.

Source

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Borrelia burgdorferi Lyme Disease



Borrelia burgdorferi is a spirochete which is the causative agent of Lyme disease, the most common tick-borne disease in the United States.



Diagnosis  of Lyme Disease
http://instructional1.calstatela.edu/nmcquee/Micro302/Group%20cases/Case%2038.ppt

Infectious Arthritis
https://medicine.med.unc.edu/education/internal-medicine-residency-program/files/ppt/8.3.09%20Jonas%20Infectious%20Arthritis.ppt

Lyme Disease and The Lyme Disease Vaccine
By Jason Hadrath
http://www.chem.uwec.edu/Chem412_S99/ppt/lyme.ppt

Lyme’s  Disease
http://www.austincc.edu/kotrla/serLymesDisease.ppt

Homology modeling  of enolase in Borrelia burgdorferi
by Andrew Jones,  Brenden O’Connell, Martine Stewart, Edwin  Suh and Amy Schumer
http://s11.middlebury.edu/MBBC0324A/STUDENTS/Structure_II/Protein_Homology_II.ppt

Lyme Disease
http://www.columbia.edu/itc/hs/nursing/m8770/2003/infectious%20diseases.ppt

Treatment of Nervous System Lyme Disease (An Evidence-Based Review)
http://www.aan.com/practice/guideline/index.cfm?fuseaction=home.view&guideline=249

Borrelia  burgdorferi Lyme disease
http://www2.yk.psu.edu/~mph13/Borrelia%20burgdorferi.ppt

Borrelia  Burgdorferi Lyme Disease
by Joenay M. Latoya B., Diamante  C.
http://www.elmhurst.edu/library/courses/workshoppages//BorreliaBurgdorferi1.ppt

Lyme’s  Disease
http://www.austincc.edu/kotrla/serLymesDisease.ppt

Transmitted  Microbial Diseases
http://people.uncw.edu/sizemorer/rkswww/PP%202011/17d%20Transmitted%20Microbial%20Diseases.ppt

Lyme  Disease “The most common tickborne infection in the United States"
http://www.plu.edu/~eatonla/doc/lyme-disease.ppt

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21 February 2012

Proprioceptive Neuromuscular Facilitation - PNF Ppt and Published articles



PNF - Propriocpetive neuromuscular facilitation is exercise based on the principles of functional human anatomy and neurophysiology

Muscle Strength  and Endurance
http://users.rowan.edu/

Proprioceptive  Neuromuscular Facilitation When  and Why?
PNFstretch.ppt

Warm-Up  and Stretching
by Ian  Jeffreys, MS; CSCS, NSCA-CPT
warmup.09.ppt

Proprioceptive Neuromuscular Facilitation
PNF patterns.ppt

Restoring  Range of Motion and Improving Flexibility Importance  of Flexibility
Improving Flexibility.ppt

Training  and Conditioning Techniques
http://www.iwu.edu/~bkauth/firstaid/326-2.ppt

Principles  of Flexibility
Flexibility.ppt

Lecture Notes in pdf format

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