13 June 2009

Dermatology



Folliculitis Decalvans
* An inflammatory reaction of the hair follicles
* Leads to cicatricial alopecia
* Small pustules surround the follicles
* Erythema, scaling, and smooth shiny depressed scars are apparent
* Pseudopelade
* When the pustules have healed and scarring remains –pseudopelade occurs
* Note intact follicles and single hairs growing
* May occur on axillae and groin as well
* Etiology is unknown
* Scarring alopecia in a middle-aged man, associated with a hyperkeratotic scale-crust with follicular hyperkeratosis and erythema

* TREATMENT:
* Cephalosporins, dicloxacillin, and azithromycin and rifampin may be added to therapy for better long-term control
* Oral zinc or vitamin C supplementation may enhance response
* Chronic inflammation reactions may be helped with topical steroids and by intralesional triamcinolone
* Thick, asbestos-like (amiantaceous), shiny scales attached to the lower part of the hair shaft, rather like tiles overlapping on a roof
* Crusting may be localized or, less commonly generalized over the entire scalp
* There are no structural changes in the hair, but in some patches where the crusting is thick, there may be purulent exudate under the crust and temporary alopecia may occur

Tinea Amiantacea
* Etiology is likely secondary to an infection occurring in seborrheic dermatitis or inverse psoriasis
* Treatment should be shampoo daily or every other day with selenium sulfide susupension, or a tar shampoo , for a few weeks
* Prior application of Baker’s P&S liquid is helpful to remove scale and crust
* Derma-Smoothe and FS shampoo are also effective
Keratosis Follicularis Contagiosa
* Also known as epidemic acne, epidemic follicular eruption, epidemic follicular keratosis, and Brooke’s disease
* Unknown etiology
* Occurs in children
Keratosis Follicularis Contagiosa
* Eruption is widespread and symmetrical, affecting chiefly the back of the neck, the shoulders, and the extensor surfaces of the extremities
* Onset is acute, may affect large numbers of patients in a localized geographic area , and spontaneously involutes over a 3-to-6-week period
* There is a horny thickening of these areas, especially pronounced about the follicles, where small black corneous may be discerned
* Etiology has been hypothesized to be infectious- but not proven

Folliculitis Nares Perforans
Perforating Folliculitis
Kyrle’s Disease
Reactive Perforating Collagenosis
Trichrome stain
Perforating Disease of Hemodialysis
Traumatic Anserine Folliculosis
Disseminate and Recurrent Infundibulofolliculitis
Lichen Spinulosus
Histology:
Treatment:
Hyperhidrosis
Gustatory Hyperhidrosis
Other Localized Forms of Hyperhidrosis
Generalized Hyperhidrosis
Treatment:
Anhidrosis= absence of sweating
Bromidrosis= fetid sweat
Chromhidrosis
Fox-Fordyce Disease
Apocrine gland sweating does not occur in areas of involvement
Treatment is difficult-No form of therapy is uniformly effective
Granulosis Rubra Nasi
Hidradenitis
Neutrophilic Eccrine Hidradenitis
Recurrent Palmoplantar Hidradenitis
Sagittal view of nail unit
Lichen Planus of Nails
Treatment is unsatisfactory-
Psoriatic Nails
Darier’s Disease
Onychomadesis
Beau’s Lines
Half and Half Nails
Muehrcke’s Lines
Mees’ Lines
Terry’s Nails
Onychorrhexis (Brittle Nails)
Onychoschizia
Pitted Nails (Stippled Nails)
Racquet Nails (Nail en Raquette)
Chevron Nail (Herringbone Nail)
Hapalonychia
Platonychia
Nail-Patella Syndrome
Other bone features
Median Nail Dystrophy
Pterygium Unguis
Onychogryphosis
Anonychia
Onychoatrophy
Onychomadesis
Beau’s Lines
Half and Half Nails
Mees’ Lines
Terry’s Nails
Onychorrhexis (Brittle Nails)
Onychoschizia
Pitted Nails (Stippled Nails) .......
Leukonychia or White Nails
Nail-Patella Syndrome
Median Nail Dystrophy
Pterygium Unguis
Pterygium Inversum Unguis
Hangnail
Pincer Nails
Onychophagia
Onychotillomania

Dermatology.ppt

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12 June 2009

Pharmacology presentations



Pharmacology presentations
by:Karyn Mills, RN, BSN
coastalbend.edu

Drugs for Hypertension
Drugs for the Reproductive System
Drugs for Bacterial Infection
DRUGS FOR SEIZURES
WHAT HAPPENS AFTER A DRUG HAS BEEN ADMINISTERED
Drugs for Heart Failure
Drugs for Dysrhythmias
Drugs for Anxiety, Daytime Sedation, and Insomnia
Drugs for Pulmonary Disorders
Drugs for Psychoses & Degenerative Diseases of the Nervous System
Drugs for Pain Control
Drugs for Skin Disorders
DRUGS FOR COAGULATION DISORDERS
Drugs for Inflammation, Allergies, & Immune Disorders
Drugs for Muscle, Bone & Joint Disorders
DRUGS FOR ENDOCRINE DISORDERS
Drugs for the ANS Autonomic Nervous System
Drugs for Kidney, Acid-Base, and Electrolyte Disorders
Drugs for GI Disorders
Drugs for Lipid Disorders
INTRODUCTION TO PHARMACOLOGY: DRUG REGULATION & APPROVAL
Drug Classes, Schedules, & Categories

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11 June 2009

Human Reproduction and Development



Human Reproduction and Development

Human Gonads
* Primary sexual organs where genes are packaged into gametes
o Male - testes
o Female - ovaries
* Secrete sex hormones
o Regulate secondary sexual traits

Male Reproductive System
vas deferens
epididymis
testis
penis
seminal vesicle
prostate gland
bulbourethral gland
urethra
bladder
scrotum

Semen = Sperm + Secretions
* Secretions from epididymis aid sperm maturation
* Seminal vesicle secretes fructose and prostaglandins
* Prostate-gland secretions buffer pH in the acidic vagina
* Bulbourethral gland secretes mucus

Prostate Cancer
* Second leading cause of death in American men
* Detection

Testicular Cancer
* About 5,000 U.S. cases per year
* Can be detected by self exam

Spermatogenesis
* Spermatogonium (2n) divides by mitosis to form primary spermatocyte (2n)
* Meiosis produces haploid spermatids
* Spermatids mature to become sperm

Other Testicular Cells
* Sertoli cells
* Leydig cells

Male Hormonal Control
Hypothalamus
Anterior Pituitary
GnRH
LH
FSH
Sertoli Cells
Leydig Cells
Testes
Testosterone
Inhibin
Formation and Development of Sperm
Female Reproductive Organs
vagina
uterus
oviduct
ovary
vagina
clitoris
oviduct
ovary
uterus
Menstrual Cycle
* The fertile period for a human female occurs on a cyclic basis
* Menstrual cycle lasts about 28 days
* Follicular phase and luteal phase

Oocytes Arrested in Meiosis I
* Girl is born with primary oocytes already in ovaries
* Each oocyte has entered meiosis I and stopped
* Meiosis resumes, one oocyte at a time, with the first menstrual cycle

Menarche to Menopause
* First menstruation, or menarche, usually occurs between ages 10-16
* Menstrual cycles continue until menopause, in a woman’s late 40s or early 50s

Ovarian Cycle
secondary oocyte
antrum
primordial follicle
corpus luteum
first polar body
* Follicle grows and matures
* Ovulation occurs
* Corpus luteum forms
Female Hormonal Control
Hypothalamus
Anterior pituitary
GnRH
LH
FSH
Ovary
Estrogen
Progesterone,
estrogens
follicle growth,
oocyte maturation
Rising estrogen stimulates surge in LH
Corpus luteum
Cycle Overview
hypothalamus
anterior pituitary
FSH
LH
FSH
LH
estrogens
FOLLICULAR PHASE
LUTEAL PHASE
menstruation
ovulation
estrogens
progesterone
Fertilization
Pregnancy
Early Divisions
Blastocyst Forms
Implantation Begins
blastocoel
inner cell mass
trophoblast
Uterine cavity
Human Chorionic Gonadotropin (hCG)
Extraembryonic Membranes
yolk sac
chorionic cavity
chorionic villi
chorion
amniotic cavity
connecting stalk
Gastrulation - Day 15
Vertebrate Body Plan Emerges
The Placenta
Embryonic Period
Fetal Period
Fetal Nutrition
Teratogens
Birth (Labor)
Lactation
Stages of Human Development - Prenatal
* Zygote - Single cell
* Morula - Solid ball of cells
* Blastocyst - Ball with fluid-filled cavity
* Embryo - 2 weeks to 8 weeks
* Fetus - 9 weeks to birth
Stages of Human Development - Postnatal
* Newborn - First 2 weeks after birth
* Infant - 2 weeks to 15 months
* Child – To 10-12 years
* Pubescent - At puberty
* Adolescent - Puberty to maturation
* Adult
* Old age
Birth Control Options
Prevent fertilization
Prevent ovulation
Block implantation
AIDS
AIDS Test
Safer Sex
Bacterial STDs
Pelvic Inflammatory Disease (PID)
Viral STDs
Abortion

Human Reproduction and Development.ppt

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