24 May 2009

Pelvic Floor Disorders: Evaluation and Treatment



Pelvic Floor Disorders: Evaluation and Treatment
By:Elisa Rodriguez Trowbridge, MD
Departments OB/GYN and Urology
Division of Female Pelvic Medicine and Reconstructive Surgery



3 General Categories of Disorders

* Urinary Incontinence
* Pelvic Organ Prolapse
* Anal Incontinence

Urinary Incontinence
Types of Urinary Incontinence
* Stress Incontinence
* Urge Incontinence
* Mixed Incontinence
* Overflow Incontinence

Stress Urinary Incontinence (SUI)
* Generally occurs with sudden movements or increases in intra-abdominal pressure- coughing, laughing, sneezing, or running.
Urge Incontinence
* Typically preceded by an urge to void, and can involve a trigger such as running water, opening a door, removing undergarments.
* Mixed urinary incontinence: Involuntary leakage associated with urgency and also with exertion, sneezing, or coughing (SUI).

Overactive Bladder
* Urgency- DRY
* Frequency- DRY
* Urge Urinary Incontinence (UUI)- WET

Urinary Incontinence- Evaluation
* History
* Exam
Incontinence Physical Exam
* Standing or Supine Stress Test
Post Void Residual & Urine Dipstick
Voiding Diary
* Normal Voiding
Overflow incontinence
* Obstruction of urethra
* Poor contractile bladder muscle
* Must find out PVR !!
** Must stop anticholinergics!!
Simple Cystometry (Urodynamics)
Multichannel Urodynamics
Indications:
* Uncertain diagnosis
* Fail respond to treatment
* Prior failed surgery
* Complex

Risk factors of UI
* Sex: Women are more likely than men to have stress incontinence –pregnancy, childbirth, and menopause.
* Age: As you get older, the muscles in your bladder and urethra lose some of their strength. Changes with age reduce how much your bladder can hold and increase the chances of involuntary urine release. However, getting older doesn't necessarily mean that you'll have incontinence. Incontinence isn't normal at any age — except during infancy.
* Obesity: Being overweight increases the pressure on your bladder.
* Smoking: A chronic cough can cause episodes of incontinence or aggravate incontinence that has other causes. Smokers are also at risk of developing overactive bladder.
* Other diseases: Having kidney disease or diabetes may increase risk of urinary incontinence.

Treatment Urinary Incontinence

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Sexual organs



Sexual organs
* Genitalia
* Reproductive tracts
* Glandular systems
* Nervous system

Women
* Genitalia
o Vulva
o Clitoris
o Vagina
* Reproductive tracts
o Ovaries
o Fallopian tubes
o Uterus
The vulva
* Mons pubis or mons veneris
* Labia majora
* Labia minora
* Prepuce or clitoral hood
* Bartholin’s glands
* Vaginal opening
* Skene’s glands
* Introitus or vestibule; vestibular bulbs
* Pubococcygeal muscles and Kegel exercises: close to 1 cm diameter
o Vaginismus and dyspareunia
* Perineum and episiotomy

The clitoris
* Glans
* Shaft
* Smegma
* Circumcision, clitoridectomy (excision), Pharaonic circumcision, and infibulation
* Urethra, between clitoris and vagina

The vagina
* Hymen or maidenhead
* Mucosal lining: Lubrication
* Nerve endings: Outer 1/3 of vagina
* Grafenberg spot

Vaginal health
* Self-examination with mirror, flashlight
* Do not douche or use vaginal deodorants
* Wash vulva daily, but do not scrub
o Insist that a sexual partner is also freshly clean
* Wear all-cotton panties
o Especially if taking antibiotics or perspiring

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Cervical/Vulvar/Vaginal Cancer



Cervical/Vulvar/Vaginal Cancer
By:Steve Remmenga, M.D.
The McClure L Smith Professor of Gynecologic Oncology
Division of Gynecologic Oncology, Department of OB/GYN
University of Nebraska Medical Center

Cervical Cancer

Cervical CA
* International estimates
Pap Smear
* With the advent of the Pap smear, the incidence of cervical cancer has dramatically declined

Cervical CA Etiology
* Cervical cancer is a sexually transmitted disease.
* HPV DNA is present in virtually all cases of cervical cancer and precursors.
* Some strains of HPV have a predilection to the genital tract and transmission is usually through sexual contact (16, 18 High Risk).
* Little understanding of why small subset of women are affected by HPV.
* HPV may be latent for many years before inducing cervical neoplasia.

Cervical CA Risk Factors
* Early age of intercourse
* Number of sexual partners
* Smoking
* Lower socioeconomic status
* High-risk male partner
* Other sexually transmitted diseases
* Up to 70% of the U.S. population is infected with HPV

Prevention
* Educate all providers, men and women regarding HPV and the link to cervical cancer.
* Adolescents are an especially high-risk group due to behavior and cervical biology.
* Delay onset of sexual intercourse.
* Condoms may help prevent sexually transmitted disease.

Screening Guidelines for the Early Detection of Cervical Cancer, American Cancer Society 2003
* Screening should begin approximately three years after a women begins having vaginal intercourse, but no later than 21 years of age.
* Screening should be done every year with regular Pap tests or every two years using liquid-based tests.
* At or after age 30, women who have had three normal test results in a row may get screened every 2-3 years. However, doctors may suggest a woman get screened more if she has certain risk factors, such as HIV infection or a weakened immune system.
* Women 70 and older who have had three or more consecutive Pap tests in the last ten years may choose to stop cervical cancer screening.
* Screening after a total hysterectomy (with removal of the cervix) is not necessary unless the surgery was done as a treatment for cervical cancer.

Pap Smear
* Single Pap false negative rate is 20%.
* The latency period from dysplasia to cancer of the cervix is variable.
* 50% of women with cervical cancer have never had a Pap smear.
* 25% of cases and 41% of deaths occur in women 65 years of age or older.

Symptoms of Invasion
* May be silent until advanced disease develops
* Post-coital bleeding
* Foul vaginal discharge
* Abnormal bleeding
* Pelvic pain
* Unilateral leg swelling or pain
* Pelvic mass
* Gross cervical lesion

Cell Type
* Squamous Cell Carcinoma 80-85%
* AdenoCarcinoma 15%
* Adenosquamous
* Others

Staging
* Clinical Staged Disease
o Physical Exam
o Blood Work
o Cystoscopy
o Proctoscopy

Read more...
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