01 May 2009

Oculomotor Lecture



Oculomotor Lecture
Presentation lecture from:Mary Warren, Uni. of Alabama at Birmingham

Evaluation Purpose

* Determine if an oculomotor impairment exists and interferes with occupational performance
o Not to diagnose the impairment
* Evaluation should be a simple screening using a “look and listen” approach
o Look at the deviations in oculomotor control
o Listen to patient complaints regarding occupational performance

Begin Evaluation by Listening

* Obtain visual history
o Congenital childhood strabismus
+ Did pt have eye surgery, patching as a child?
+ Did anyone ever tell the patient h/she had a lazy eye?
o If patient had a head injury
+ Was there any trauma to the eye or orbit?

* What are the patient’s functional complaints?
o Print blurs when reading
o Unable to keep objects in focus
o Balance difficulty
o Past pointing/reaching
o Eye fatigue/eye pain/headache with sustained focus
o Difficulty maintaining concentration on activities requiring sustained focus
+ Reading or computer work
o Nausea/blurring vision with head movement
o Blurring of vision when changing focal distances

Assessment of Diplopia

* Subjective complaints of diplopia
o Lateral or vertical splitting of images
o Present at near distances or far distances
o Present intermittently or constantly
o Direction of affected gaze
+ Primary gaze
+ Right or left gaze
+ All gaze directions
o Minimize or exacerbated by head position
o Accompanied by blurring vision when head movement

* Objective observations
o Disappears when one eye is closed
+ Indicates oculomotor impairment
o Remains with closing of one eye
+ Indicates some other cause such as retinal injury
o Area of fusion
+ All persons have some area where they can see a single image known as the fusion zone
+ Distance from face
+ Ability to maintain fusion within the zone
o Neck range of motion
+ Horizontal and vertical

General Appearance of Eyes and Head

* Have pt focus on a distant, visible target and compare appearance of the eyes
o Symmetry of pupil size
o Symmetry and function of eyelids
o Presence of nystagmus
* Does patient assume a deviated head position?
* Observe symmetry of corneal reflections in primary gaze

Corneal Reflections

* Spot of light reflected off the cornea of the eyes.
* Observation of corneal reflections is one of the simplest ways to assess ocular alignment.

* When eyes are aligned the reflections should match in location (note: some persons have slightly unequal reflections due to corneal imperfections).
* Known as Hirschberg test

Corneal Reflections Test

* Test materials
o Recording form
o Penlight
o Distant interesting target large enough to be seen easily at 6 plus feet
* Environment
o Well lighted room; ensure light source is not shining directly into the patient’s eyes. Room illumination can be decreased if corneal reflections are difficult to see.

* Procedure:
o Patient should have glasses on if worn
o Instruct the patient to focus on the target held at eye level
o Hold the penlight centered in front of the patient’s face approximately 12 inches from the tip of the nose; hold the penlight vertically so the light is directed upward and not shining into the patient’s eyes

Observe the cornea reflection in each eye
as the patient fixates

Examples of Corneal Reflections
Esotropia: reflection is on the outer rim of the cornea

Corneal Reflections Test
Assessment of Eye Movements
Smooth Pursuits
Recording
Example
Convergence
Recording
Eye Movements
Diplopia Testing
Cover Uncover Test
Outward movement: esotropia
Inward movement: exotropia
Downward movement: hypertropia
Upward movement: hypotropia
Alternate Cover Test
Diplopia Tests
Evaluating the Low Functioning Patient
Treatment
Performance Areas Affected by Oculomotor Dysfunction
Considerations in Treatment
OT Treatment Approach
Management Techniques
Occlusion
Prisms
Occlusion
Complete Occlusion
Partial Occlusion
Both Types of Occlusion
Prism
Restoration Techniques
Eye exercises
Surgical intervention

Oculomotor Lecture.ppt

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Surgical Outcomes in Intermittent Exotropia



Surgical Outcomes in Intermittent Exotropia
Presentation lecture by:
Jeffrey D. Colburn, M.D., PGY-3
Preceptor: David Morrison, M.D.
Vanderbilt Eye Institute

Intermittent Exotropia

* Intermittent exotropia x(t) is a latent tendency (phoria) for the eyes to turn out, which is intermittently controlled by fusional convergence.
* Characteristics
o Typically good bifoveal fusion and stereoacuity when aligned.
o Amblyopia is rare in x(t).
o X(t) Tends to remain stable or progress.
o Progression might result in dense suppression.

Intermittent Exotropia

* X(t) Sub-types
1. Basic
+ Angle is equal at near & distance

2. Pseudo-divergence excess (PDE)
+ Angle is equal at near & distance but appears larger in distance because of masking

3. True divergence excess (TDE)
+ Angle is larger in distance

4. Convergence insufficiency (CI)
+ Angle is larger at near

Surgical Treatment

* Goals
o Improve alignment & control
o Improve binocular vision
* Basic concepts
o Recession (weakening procedure)
o Resection (strengthening procedure)
* Two primary approaches
o Bilateral lateral rectus recession (BLRc)
o Unilateral recess & resect (R&R)

Predictors of Outcomes

age
pre-op deviation
pre-op control
sub-type
procedure type
asymmetric accommodation
pre-op deviation
central fusion or stereopsis
Observations

* Effect of pre-operative angle size on surgical outcomes in x(t) patients.
* Disparate opinions on the more successful procedure for x(t).
Hypotheses
* Larger angle x(t) patients have more successful surgical outcomes than smaller angle x(t) patients.
* R&R procedures have more successful surgical outcomes than BLRc in the management of x(t).
Methods

* Retrospective chart review
o Inclusion criteria
+ X(t) surgical cases
+ January, 2003 through January, 2008
+ Age ≤ 18 years
Methods

* Exclusion criteria
o Developmental delay
o Vertical deviation
o Pattern deviation
o Prior surgery
o Partially or untreated amblyopia
o Monocular exotropia
o Constant exotropia
o Secondary exotropia
o Nystagmus

Data collection

* Variables considered
o Gender
o Age at time of surgery
o X(t) sub-type
o Pre-op deviation
o Stereo-acuity
o Presence of fusion
o Presence of suppression
o Procedure type
o Deviation post-op visit #1
o Deviation post-op visit #2

Outcome Measures

* Surgical success:
o Intermittent exotropia ≤ 8 PD
o No esotropia
* Surgical failure:
o Not meeting above success criteria
o Repeat surgery for poor control
* Time to surgical failure
* Over-correction or under-correction

Demographics
History of amblyopia
Average pre-op deviation (PD)
Mean age at surgery (mos)
Characteristic Results

* Overall outcomes
o 61 BLRc, 19 R&R, 2 unilateral LRc
o 42 (51.2%) patients failed
o Mean time to failure was 6.9 months (1-34)
o 35 patients (43%) were under corrected
o 6 patients (7.3%) were over corrected

Other variables
Multivariate logistic regression
Surgical procedure (blrc vs. r&r)
Presence of suppression
Presence of fusion
Stereo acuity
Pre-operative deviation
Chi-square
Multivariate survival analysis
Cox proportional hazards model
Surgical procedure
Stereo Acuity
Presence of Suppression
Comment
Summary

Surgical Outcomes in Intermittent Exotropia.ppt

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30 April 2009

Sex Menopause and Aging



Sex,Menopause and Aging
Presentation by: Dr. Penny Frohlich
University of Texas at Austin

Sex,Menopause and Aging

Overview
The menopause transition
Sexual changes during and after menopause
Early menopause
Hormone replacement therapy
Aging and sexuality in men and women
The “andropause” - male menopause?


MenopauseOvaries become less responsive to FSH and LH
Patterns of GnRH release from the hypothalamus become altered
Pituitary gland becomes less responsive to GnRH

PerimenopauseAverage age at onset in the late 40’s
Irregular menstrual cycles
Somatic and psychological symptoms emerge

Post-menopause12 months of amenorrhea
Elevated FSH levels
On average, reached by the early 50’s

Is that all?No! The ovaries continue to produce androgens after menopause!

Factors that may affect timing of menopauseSmoking
Genetics
Number of pregnancies
Body mass

Symptoms of menopause Hot flashes
Mood swings
Vaginal dryness
Vaginal atrophy
Fatigue, weight gain, sleep disorders, headache, cognitive changes…..

Menopause across culturesDo all women experience menopause as a major negative life event?

Sexual changes at menopauseDecreased sexual desire
Lower levels of vaginal lubrication
More painful sexual intercourse
What doesn’t change?

Early menopauseSurgical menopause
Removal of the ovaries, usually accompanied by hysterectomy
Menopause induced by treatment for cancer
Radiation therapy
Chemotherapy
Early natural menopause

Early natural menopauseAutoimmune disorders
Genetics
Problems in ovarian development
Chromosomal irregularity
Triple X syndrome
Faulty second X chromosome

Hormone replacementEstrogen: systemic or local
Estrogen + progesterone
Androgen replacement?
Potential benefits
Possible side effects

Aging and sexualityHow do you tell what is caused by menopause and what is caused by natural aging?
A recent longitudinal study concluded that sexual arousal and orgasm are affected by both aging and menopause

Sexuality in the elderlyHealthy sexual relationships may continue into old age
Common problems associated with aging include:
Sexual dysfunction
Death of partner
Cultural attitudes towards sexuality
Health problems

The “andropause”Progressive decline of androgens over time
Symptoms: erectile dysfunction, cognitive impairment, fatigue, vague somatic symptoms
40% of men have ED by age 40
Over two-thirds of men by age 70
Is the andropause a disorder?

Sex,Menopause and Aging.ppt

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