01 May 2009

Oculomotor Lecture



Oculomotor Lecture
Presentation lecture from:Mary Warren, Uni. of Alabama at Birmingham

Evaluation Purpose

* Determine if an oculomotor impairment exists and interferes with occupational performance
o Not to diagnose the impairment
* Evaluation should be a simple screening using a “look and listen” approach
o Look at the deviations in oculomotor control
o Listen to patient complaints regarding occupational performance

Begin Evaluation by Listening

* Obtain visual history
o Congenital childhood strabismus
+ Did pt have eye surgery, patching as a child?
+ Did anyone ever tell the patient h/she had a lazy eye?
o If patient had a head injury
+ Was there any trauma to the eye or orbit?

* What are the patient’s functional complaints?
o Print blurs when reading
o Unable to keep objects in focus
o Balance difficulty
o Past pointing/reaching
o Eye fatigue/eye pain/headache with sustained focus
o Difficulty maintaining concentration on activities requiring sustained focus
+ Reading or computer work
o Nausea/blurring vision with head movement
o Blurring of vision when changing focal distances

Assessment of Diplopia

* Subjective complaints of diplopia
o Lateral or vertical splitting of images
o Present at near distances or far distances
o Present intermittently or constantly
o Direction of affected gaze
+ Primary gaze
+ Right or left gaze
+ All gaze directions
o Minimize or exacerbated by head position
o Accompanied by blurring vision when head movement

* Objective observations
o Disappears when one eye is closed
+ Indicates oculomotor impairment
o Remains with closing of one eye
+ Indicates some other cause such as retinal injury
o Area of fusion
+ All persons have some area where they can see a single image known as the fusion zone
+ Distance from face
+ Ability to maintain fusion within the zone
o Neck range of motion
+ Horizontal and vertical

General Appearance of Eyes and Head

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Surgical Outcomes in Intermittent Exotropia



Surgical Outcomes in Intermittent Exotropia
Presentation lecture by:
Jeffrey D. Colburn, M.D., PGY-3
Preceptor: David Morrison, M.D.
Vanderbilt Eye Institute

Intermittent Exotropia

* Intermittent exotropia x(t) is a latent tendency (phoria) for the eyes to turn out, which is intermittently controlled by fusional convergence.
* Characteristics
o Typically good bifoveal fusion and stereoacuity when aligned.
o Amblyopia is rare in x(t).
o X(t) Tends to remain stable or progress.
o Progression might result in dense suppression.

Intermittent Exotropia

* X(t) Sub-types
1. Basic
+ Angle is equal at near & distance

2. Pseudo-divergence excess (PDE)
+ Angle is equal at near & distance but appears larger in distance because of masking

3. True divergence excess (TDE)
+ Angle is larger in distance

4. Convergence insufficiency (CI)
+ Angle is larger at near

Surgical Treatment

* Goals
o Improve alignment & control
o Improve binocular vision
* Basic concepts
o Recession (weakening procedure)
o Resection (strengthening procedure)
* Two primary approaches
o Bilateral lateral rectus recession (BLRc)
o Unilateral recess & resect (R&R)

Predictors of Outcomes

age
pre-op deviation
pre-op control
sub-type
procedure type
asymmetric accommodation
pre-op deviation
central fusion or stereopsis
Observations

* Effect of pre-operative angle size on surgical outcomes in x(t) patients.
* Disparate opinions on the more successful procedure for x(t).
Hypotheses
* Larger angle x(t) patients have more successful surgical outcomes than smaller angle x(t) patients.
* R&R procedures have more successful surgical outcomes than BLRc in the management of x(t).
Methods

* Retrospective chart review
o Inclusion criteria
+ X(t) surgical cases
+ January, 2003 through January, 2008
+ Age ≤ 18 years
Methods

* Exclusion criteria
o Developmental delay
o Vertical deviation
o Pattern deviation
o Prior surgery
o Partially or untreated amblyopia
o Monocular exotropia
o Constant exotropia
o Secondary exotropia
o Nystagmus

Data collection

* Variables considered
o Gender
o Age at time of surgery
o X(t) sub-type
o Pre-op deviation
o Stereo-acuity
o Presence of fusion
o Presence of suppression
o Procedure type
o Deviation post-op visit #1
o Deviation post-op visit #2

Outcome Measures

* Surgical success:
o Intermittent exotropia ≤ 8 PD
o No esotropia
* Surgical failure:
o Not meeting above success criteria
o Repeat surgery for poor control
* Time to surgical failure
* Over-correction or under-correction

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30 April 2009

Sex Menopause and Aging



Sex,Menopause and Aging
Presentation by: Dr. Penny Frohlich
University of Texas at Austin

Sex,Menopause and Aging

Overview
The menopause transition
Sexual changes during and after menopause
Early menopause
Hormone replacement therapy
Aging and sexuality in men and women
The “andropause” - male menopause?


MenopauseOvaries become less responsive to FSH and LH
Patterns of GnRH release from the hypothalamus become altered
Pituitary gland becomes less responsive to GnRH

PerimenopauseAverage age at onset in the late 40’s
Irregular menstrual cycles
Somatic and psychological symptoms emerge

Post-menopause12 months of amenorrhea
Elevated FSH levels
On average, reached by the early 50’s

Is that all?No! The ovaries continue to produce androgens after menopause!

Factors that may affect timing of menopauseSmoking
Genetics
Number of pregnancies
Body mass

Symptoms of menopause Hot flashes

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