Wiskott-Aldrich Syndrome

The Wiskott-Aldrich Syndrome: An X-linked Primary Immunodeficiency
Kristin Goff
The Wiskott-Aldrich Syndrome.ppt

Wiskott Aldrich Syndrome Treatment
The Wiskott-Aldrich Syndrome.ppt

Immunodeficiency
Immunodeficiency.ppt

Primary Immunodeficiency
Regina D. Wells, MD
Immune_System_for_the_Boards.ppt

Wiskott-Aldrich Syndrome (WAS)
Wiskott-Aldrich Syndrome (WAS).ppt

Transfusion Associated Graft versus Host Disease TAGvHD
Lloyd O. Cook, M.D.
TransfusionAssociatedGraftversusHostDisease.ppt

Immunodeficiencies
Immunodeficiencies.ppt

Protein Ontologies and Protein Disorder
A. Keith Dunker
Protein Ontologies and Protein Disorder.ppt

Heme-Onc Grand Rounds Case Presentation
Case Presentation.ppt

Clinical Coagulation
QualPLTs.ppt

Atopic Dermatitis, Eczema, and Noninfectious Immunodeficiency Disorders
Atopic Dermatitis.ppt

Platelet structure
Platelet structure disorders.ppt
200 scholarly articles free access

1. Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, North India.
2. The chemotactic defect in wiskott-Aldrich syndrome macrophages is due to the reduced persistence of directional protrusions.
3. Prolonged survival after splenectomy in Wiskott-Aldrich syndrome: a case report.
4. The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.
5. Long-term observation of herpes simplex virus type 1 HSV-1 infection in a child with Wiskott-Aldrich syndrome and a possible reactivation mechanism for thymidine kinase-negative HSV-1 in humans.
6. Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells.
7. A peptide derived from the Wiskott-Aldrich syndrome WAS protein-interacting protein WIP restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding.
8. Occurrence of aortic aneurysms in 5 cases of Wiskott-Aldrich syndrome.
9. Stem-cell gene therapy for the Wiskott-Aldrich syndrome.
10. Spurious case of XX maleness in a patient with a history of Wiskott-Aldrich syndrome.
11. The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets.
12. Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.
13. Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 WH2 domains of Spire and the implication for filament nucleation.
14. WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein WASP family are controlled by analogous structurally related complexes.
15. Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: advances in biology and future directions for treatment.
16. Systemic autoimmunity and defective Fas ligand secretion in the absence of the Wiskott-Aldrich syndrome protein.
17. Functional characterization of Wiskott-Aldrich syndrome protein and scar homolog WASH, a bi-modular nucleation-promoting factor able to interact with biogenesis of lysosome-related organelle subunit 2 BLOS2 and gamma-tubulin.
18. Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice.
19. Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.
20. New insights into the biology of Wiskott-Aldrich syndrome WAS.
21. Efficient transcriptional targeting of human hematopoietic stem cells and blood cell lineages by lentiviral vectors containing the regulatory element of the Wiskott-Aldrich syndrome gene.
22. Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein WASP and neural-WASP.
23. Phenotypic and genotypic correction of WASP gene mutation in Wiskott-Aldrich syndrome by unrelated cord blood stem cell transplantation.
24. Wiskott-Aldrich syndrome protein is an effector of Kit signaling.
25. Wiskott-Aldrich Syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation.
26. The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.
27. Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.
28. Sorting nexin 33 induces mammalian cell micronucleated phenotype and actin polymerization by interacting with Wiskott-Aldrich syndrome protein.
29. Recent advances in understanding the pathophysiology of Wiskott-Aldrich syndrome.
30. The Wiskott-Aldrich syndrome protein is required for iNKT cell maturation and function.
31. Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.
32. A large kindred with X-linked neutropenia with an I294T mutation of the Wiskott-Aldrich syndrome gene.
33. Evolution of highly polymorphic T cell populations in siblings with the Wiskott-Aldrich Syndrome.
34. Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis.
35. Expression of Wiskott-Aldrich syndrome protein in dendritic cells regulates synapse formation and activation of naive CD8+ T cells.
36. Unprecedented diversity of genotypic revertants in lymphocytes of a patient with Wiskott-Aldrich syndrome.
37. Unrelated bone marrow transplantation with a reduced toxicity myeloablative conditioning regimen in Wiskott-Aldrich syndrome.
38. Persistent thrombocytopenia in a child: morphological examination of blood platelets established the diagnosis of Wiskott-Aldrich syndrome.
39. Development of lentiviral gene therapy for Wiskott Aldrich syndrome.
40. Percutaneous closure of false aneurysms of the aorta in Wiskott Aldrich syndrome.
41. A familial case of Wiskott-Aldrich Syndrome with a hotspot mutation in exon 2 of the WAS Gene.
42. Hematopoietic stem cell transplantation for patients with Wiskott-Aldrich syndrome.
43. Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation.
44. Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages.
45. Wiskott Aldrich syndrome protein WASP and N-WASP are critical for T cell development.
46. Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein.
47. Impaired LPS-induced signaling in microglia overexpressing the Wiskott-Aldrich syndrome protein N-terminal domain.
48. Surgical resection of sequential thoracic aortic aneurysms in Wiskott-Aldrich syndrome.
49. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.
50. Large granular lymphocyte proliferation and revertant mosaicism: two rare events in a Wiskott-Aldrich syndrome patient.
51. A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein.
52. Requirement for a complex of Wiskott-Aldrich syndrome protein WASP with WASP interacting protein in podosome formation in macrophages.
53. The Wiskott-Aldrich syndrome protein is required for the function of CD4+CD25+Foxp3+ regulatory T cells.
54. Interaction of the Wiskott-Aldrich syndrome protein with sorting nexin 9 is required for CD28 endocytosis and cosignaling in T cells.
55. Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.
56. WIP is a chaperone for Wiskott-Aldrich syndrome protein WASP.
57. The expression of Wiskott-Aldrich syndrome protein WASP is dependent on WASP-interacting protein WIP.
58. Hyaluronan-CD44 interaction with neural Wiskott-Aldrich syndrome protein N-WASP promotes actin polymerization and ErbB2 activation leading to beta-catenin nuclear translocation, transcriptional up-regulation, and cell migration in ovarian tumor cells.
59. Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.
60. Increased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 correlated with poor prognosis of hepatocellular carcinoma.
61. Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia.
62. A complex of Wiskott-Aldrich syndrome protein with mammalian verprolins plays an important role in monocyte chemotaxis.
63. Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung.
64. Wiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesion.
65. Intrabodies against the EVH1 domain of Wiskott-Aldrich syndrome protein inhibit T cell receptor signaling in transgenic mice T cells.
66. Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein WASP/neuronal WASP.
67. Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein.
68. Actin-bound structures of Wiskott-Aldrich syndrome protein WASP-homology domain 2 and the implications for filament assembly.
69. Analysis of T-cell repertoire diversity in Wiskott-Aldrich syndrome.
70. Genotype-proteotype linkage in the Wiskott-Aldrich syndrome.
71. Molecular pathogenesis of Wiskott-Aldrich syndrome.
72. Mosaicism of NK cells in a patient with Wiskott-Aldrich syndrome.
73. The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.
74. The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein.
75. The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B RelA independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement.
76. Wiskott-Aldrich syndrome protein is needed for vaccinia virus pathogenesis.
77. Phenotypic perturbation of B cells in the Wiskott-Aldrich syndrome.
78. Wiskott-Aldrich syndrome: another piece in the puzzle.
79. A neural Wiskott-Aldrich Syndrome protein-mediated pathway for localized activation of actin polymerization that is regulated by cortactin.
80. Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein.
81. ARPC1/Arc40 mediates the interaction of the actin-related protein 2 and 3 complex with Wiskott-Aldrich syndrome protein family activators.
82. Wiskott-Aldrich syndrome protein deficiency leads to reduced B-cell adhesion, migration, and homing, and a delayed humoral immune response.
83. A neural-specific splicing event generates an active form of the Wiskott-Aldrich syndrome protein.
84. Mutations of the Wiskott-Aldrich Syndrome Protein WASP: hotspots, effect on transcription, and translation and phenotype/genotype correlation.
85. Differential roles for Wiskott-Aldrich syndrome protein in immune synapse formation and IL-2 production.
86. Cutting edge: selective requirement for the Wiskott-Aldrich syndrome protein in cytokine, but not chemokine, secretion by CD4+ T cells.
87. Multiple patients with revertant mosaicism in a single Wiskott-Aldrich syndrome family.
88. Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein WASp for their morphology.
89. Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptosporidium parvum.
90. Polarized hyphal growth in Candida albicans requires the Wiskott-Aldrich Syndrome protein homolog Wal1p.
91. Signalling to actin assembly via the WASP Wiskott-Aldrich syndrome protein-family proteins and the Arp2/3 complex.
92. Early deficit of lymphocytes in Wiskott-Aldrich syndrome: possible role of WASP in human lymphocyte maturation.
93. Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.
94. Identification of splicing variants of Rapostlin, a novel RND2 effector that interacts with neural Wiskott-Aldrich syndrome protein and induces neurite branching.
95. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein WASp tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.
96. Impaired signaling via the high-affinity IgE receptor in Wiskott-Aldrich syndrome protein-deficient mast cells.
97. Differential contribution of Wiskott-Aldrich syndrome protein to selective advantage in T- and B-cell lineages.
98. SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site.
99. Defects in T-cell-mediated immunity to influenza virus in murine Wiskott-Aldrich syndrome are corrected by oncoretroviral vector-mediated gene transfer into repopulating hematopoietic cells.
100. Isolated EBV lymphoproliferative disease in a child with Wiskott-Aldrich syndrome manifesting as cutaneous lymphomatoid granulomatosis and responsive to anti-CD20 immunotherapy.
101. Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein WAVE and Rac1 in the phagocytosis of amyloid-beta1-42 in rat microglia.
102. Efficient antigen presentation of soluble, but not particulate, antigen in the absence of Wiskott-Aldrich syndrome protein.
103. A defect in hematopoietic stem cell migration explains the nonrandom X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome.
104. Second-site mutation in the Wiskott-Aldrich syndrome WAS protein gene causes somatic mosaicism in two WAS siblings.
105. Wiskott-Aldrich syndrome: the possibilities of diagnosis and treatment.
106. Macrophages of patients with X-linked thrombocytopenia display an attenuated Wiskott-Aldrich syndrome phenotype.
107. Direct binding of a fragment of the Wiskott-Aldrich syndrome protein to the C-terminal end of the anaphylatoxin C5a receptor.
108. Effects of ectopically expressed neuronal Wiskott-Aldrich syndrome protein domains on Rickettsia rickettsii actin-based motility.
109. Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor.
110. Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice.
111. Wiskott-Aldrich syndrome in a female.
112. Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein.
113. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses.
114. Mixed chimera status of 12 patients with Wiskott-Aldrich syndrome WAS after hematopoietic stem cell transplantation: evaluation by flow cytometric analysis of intracellular WAS protein expression.
115. The Wiskott-Aldrich syndrome.
116. Correction of the murine Wiskott-Aldrich syndrome phenotype by hematopoietic stem cell transplantation.
117. Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein WASP, WASP-interacting protein WIP, and ELMO1.
118. Neural Wiskott-Aldrich syndrome protein is involved in hepatocyte growth factor-induced migration, invasion, and tubulogenesis of epithelial cells.
119. The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein WIP, may antagonistically regulate type I myosins in Saccharomyces cerevisiae.
120. Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts.
121. The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein WASp-mediated actin polymerization to T cell antigen receptor endocytosis.
122. The rat homologue of Wiskott-Aldrich syndrome protein WASP-interacting protein WIP associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation.
123. Activation of Arp2/3 complex by Wiskott-Aldrich Syndrome protein is linked to enhanced binding of ATP to Arp2.
124. Overexpression of the Wiskott-Aldrich syndrome protein N-terminal domain in transgenic mice inhibits T cell proliferative responses via TCR signaling without affecting cytoskeletal rearrangements.
125. Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes.
126. The verprolin-like central vc region of Wiskott-Aldrich syndrome protein induces Arp2/3 complex-dependent actin nucleation.
127. Somatic mosaicism in Wiskott--Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism.
128. Identification of another actin-related protein Arp 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein N-WASP that complements actin polymerization induced by the Arp2/3 complex activating VCA domain of N-WASP.
129. Accidental busulfan overdose: enhanced drug clearance with hemodialysis in a child with Wiskott-Aldrich syndrome.
130. CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.
131. Spontaneous in vivo reversion of an inherited mutation in the Wiskott-Aldrich syndrome.
132. Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells.
133. A role for Wiskott-Aldrich syndrome protein in T-cell receptor-mediated transcriptional activation independent of actin polymerization.
134. Impact of donor type on outcome of bone marrow transplantation for Wiskott-Aldrich syndrome: collaborative study of the International Bone Marrow Transplant Registry and the National Marrow Donor Program.
135. Coiling phagocytosis of Borrelia burgdorferi by primary human macrophages is controlled by CDC42Hs and Rac1 and involves recruitment of Wiskott-Aldrich syndrome protein and Arp2/3 complex.
136. A novel neural Wiskott-Aldrich syndrome protein N-WASP binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42.
137. Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling.
138. Activation by Cdc42 and PIP2 of Wiskott-Aldrich syndrome protein WASp stimulates actin nucleation by Arp2/3 complex.
139. Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold.
140. Unrelated partially matched peripheral blood stem cell transplantation with highly purified CD34+ cells in a child with Wiskott-Aldrich syndrome.
141. Determination of carrier status for the Wiskott-Aldrich syndrome by flow cytometric analysis of Wiskott-Aldrich syndrome protein expression in peripheral blood mononuclear cells.
142. The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.
143. GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein N-WASp with actin-related protein ARP2/3 complex.
144. Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis.
145. Essential role of neural Wiskott-Aldrich syndrome protein in neurite extension in PC12 cells and rat hippocampal primary culture cells.
146. The Wiskott-Aldrich syndrome.
147. Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules.
148. Cutting edge: WIP, a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation.
149. Expression of human Wiskott-Aldrich syndrome protein in patients' cells leads to partial correction of a phenotypic abnormality of cell surface glycoproteins.
150. X-linked thrombocytopenia identified by flow cytometric demonstration of defective Wiskott-Aldrich syndrome protein in lymphocytes.
151. Wiskott-Aldrich syndrome: molecular pieces slide into place.
152. Spontaneous apoptosis in lymphocytes from patients with Wiskott-Aldrich syndrome: correlation of accelerated cell death and attenuated bcl-2 expression.
153. WASP levels in platelets and lymphocytes of wiskott-aldrich syndrome patients correlate with cell dysfunction.
154. Systemic vasculitis and aneurysm formation in the Wiskott-Aldrich syndrome.
155. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes.
156. The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.
157. Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42.
158. Allogeneic peripheral blood stem cell transplantation in a Wiskott-Aldrich syndrome patient.
159. Retrovirus-mediated WASP gene transfer corrects defective actin polymerization in B cell lines from Wiskott-Aldrich syndrome patients carrying 'null' mutations.
160. Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages.
161. The thrombocytopenia of Wiskott Aldrich syndrome is not related to a defect in proplatelet formation.
162. Flow cytometric analysis of Wiskott-Aldrich syndrome WAS protein in lymphocytes from WAS patients and their familial carriers.
163. Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein WASP with WASP interacting protein.
164. Involvement of wiskott-aldrich syndrome protein in B-cell cytoplasmic tyrosine kinase pathway.
165. Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein.
166. Collagen induces tyrosine phosphorylation of Wiskott-Aldrich syndrome protein in human platelets.
167. The Wiskott-Aldrich syndrome protein-interacting protein WIP binds to the adaptor protein Nck.
168. The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein WASP is necessary but not sufficient for tight binding to Cdc42 and structure formation.
169. A case of Wiskott-Aldrich syndrome with dual mutations in exon 10 of the WASP gene: an additional de novo one-base insertion, which restores frame shift due to an inherent one-base deletion, detected in the major population of the patient's peripheral blood lymphocytes.
170. X-linked Wiskott-Aldrich syndrome in a girl.
171. A 5' regulatory sequence containing two Ets motifs controls the expression of the Wiskott-Aldrich syndrome protein WASP gene in human hematopoietic cells.
172. Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri.
173. Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein.
174. WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells.
175. X-linked Wiskott-Aldrich syndrome in a girl.
176. Treatment of acyclovir-resistant herpes simplex virus keratitis in a patient with Wiskott-Aldrich syndrome.
177. Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype.
178. Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells.
179. Expression of Wiskott-Aldrich syndrome protein WASP gene during hematopoietic differentiation.
180. Tyrosine kinase signaling regulates Wiskott-Aldrich syndrome protein function, which is essential for megakaryocyte differentiation.
181. Intravenous immunoglobulin, splenectomy, and antibiotic prophylaxis in Wiskott-Aldrich syndrome.
182. Multiple antigens are altered on T and B lymphocytes from peripheral blood and spleen of patients with Wiskott-Aldrich syndrome.
183. Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains.
184. Wiskott-Aldrich syndrome--a truly interdisciplinary problem.
185. Fatal outcome of renal transplantation in a patient with the Wiskott-Aldrich syndrome.
186. Wiskott-Aldrich syndrome is a "wonderful mystery".
187. Studies of the expression of the Wiskott-Aldrich syndrome protein.
188. The enigma of the Wiskott-Aldrich syndrome begins to unravel.
189. Wiskott-Aldrich syndrome: report of an autosomal dominant variant.
190. Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42.
191. Defects in Wiskott-Aldrich syndrome blood cells.
192. Unrelated bone marrow transplantation in a Wiskott-Aldrich syndrome patient sharing two HLA-extended haplotypes with the donor.
193. The Wiskott-Aldrich syndrome and X-linked congenital thrombocytopenia are caused by mutations of the same gene.
194. High prevalence of nonsense, frame shift, and splice-site mutations in 16 patients with full-blown Wiskott-Aldrich syndrome.
195. Expansion of large granular lymphocyte subsets in Wiskott-Aldrich syndrome.
196. Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains.
197. Evidence for antigenic selection of large granular lymphocytes in a patient with Wiskott-Aldrich syndrome.
198. A variant of Wiskott-Aldrich syndrome with nephropathy is linked to DXS255.
199. Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene.
200. Nonrandom inactivation of the X chromosome in early lineage hematopoietic cells in carriers of Wiskott-Aldrich syndrome.