Bipolar Disorder in DSM-IV

Bipolar Disorder in DSM-IV
* Bipolar I disorder: manic episode(s)
or mixed episode(s) plus MDE(s)
* Bipolar II disorder: major depressive episode(s) plus hypomanic episode(s)
* Cyclothymia: hypomanic symptoms
plus depressive symptoms

Bipolar Disorders: DSM-IV Nosology
Criteria
Mania
Hypomania
Major depression
Mixed state
BPD I
BPD II
Manic Episode: Diagnostic Criteria
Manic Episode: Differential Diagnoses
Hypomanic episode
Mixed episode
History of treatment for depression
Differential diagnosis
* Physical
* Psychological
Mixed Episode: Diagnostic Criteria
Characteristics BPD I BPD II
Ethnic/racial differential
Gender differential M = F F›M (?)
Bipolar Disorders: Epidemiology
Characteristics BPD I BPD II
Bipolar Disorders: Epidemiology
Epidemiology
Diagnostic Dilemmas:
Unipolar Versus Bipolar
Unipolar
Etiology
Heritability
ADOPTION STUDIES
Cognitive Deficits
* Working memory
* Sustained attention
* Abstract reasoning
* Visuomotor skills
* Verbal memory
* Verbal fluency
* Cognitive flexibility
* General cognitive functioning
Potential Explanations for Cognitive Deficits
* Iatrogenic or Alcohol use
* Temporary functional changes
* Degenerative brain changes
* Permanent structural lesions
* Permanent functional alterations of neural networks underlying affect and cognition

Alcohol Use
Iatrogenic
Temporal Functional Deficits
Summary

Bipolar Disorder in DSM-IV.ppt