Showing posts with label General. Show all posts
Showing posts with label General. Show all posts

24 June 2009

Journal Title Abbreviations



Journal Title Abbreviations

Biological Journals And Abbreviations: http://home.ncifcrf.gov/research/bja/

ISI Journal Abbreviations Index: http://library.caltech.edu/reference/abbreviations/
Journal titles covered by ISI: Institute of Scientific Information.

Journals Title Abbreviations: http://www.library.ubc.ca/scieng/coden.html
From the Science and Engineering Library, University of British Columbia

Mathematical Reviews' Abbreviations of Names of Serials: http://www.ams.org/mathscinet/searchjournals

Medline Journal Abbreviations: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Journals
Just type in your abbreviated journal title.

If you do not find your title using any of the resources above, the following website links to several other journal abbreviation sources:

All That JAS: Journal Abbreviation Sources: http://www.public.iastate.edu/~CYBERSTACKS/JAS.htm

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31 May 2009

Continuing Medical Education (CME) Presentations



Stritch School of Medicine
Department of Continuing Medical Education (CME) Presentations

Inpatient Glycemic Control: A Hospitalist’s Perspective
By:Greg Maynard MD

Endocarditis
By Eric Muller

Overview of Hepatorenal Syndrome

Cancer Survivorship Programs:Bridging the Gap between Primary Care and Oncology
By:Patricia Robinson, M.D.

Multiple Myeloma

Serotonin Syndrome


IMPORTANT INFORMATION FOR HEALTH CARE PROFESSIONALS
by:Susan Nedza MD

Adrenal Crisis
by:Erin Lowery, PGY-3 Med-Peds
Chris Hughes

Dermatology for Boards


Non-access Related Infections in Dialysis Patients

Renal Cell Carcinoma

EVOLVING PERSPECTIVES IN THE MANAGEMENT OF ATRIAL FIBRILLATION
by:David Wilber MD

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30 May 2009

Community Clinic Presentations



Community Clinic Presentations
from Oklahoma State University

Determine Need for Rural Doctor

EBM Handout.pdf

Videoconferencing Presentation

2008 Economics of Health Care TP

Monograph Series 2005.pdf

Non-Physician Clinicians in Workforce TP

Standards of Medical Care in Diabetes - 2008

Overview of RH in Turning Point

Jackson RURAL EMERGENCY MEDICINE

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20 May 2009

PubMed Search Engines Resource Guide



PubMed Search Engines Resource Guide

This information is provided by Margaret Henderson, Librarian VCU Libraries

There is more than one way to search the medical literature (PubMed) stored at the National Library of Medicine. Entrez is the search engine created by NLM to search PubMed, but just like there are multiple search engines to search the Internet (Google, Netscape, etc.) there are multiple engines that can be used to search PubMed. As different groups and people have needed different things from the literature, they have created front-ends or 3rd party tools to search the medical literature. Some of these PubMed interfaces are useful if your specific needs correspond to those of the search tool.

Full details here

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02 May 2009

Evidence Based Health Care video presentations



Evidence Based Health Care video presentations
from University of Wisconsin

Date
Presentation
04/22/2009 Picture from The Clinical Surgeon-Scientist: An Oxymoron or a New Paradigm? video
L. Kao
01/13/2009 Picture from Evidence-Based Research: Finding Resources video
U. Dieterle

Picture from Evidence-Based Research: The Basics video
U. Dieterle
05/14/2008 Picture from Evidence-Based Community Health: From Information to Action video
F. White
01/25/2008 Picture from The End of Evidence-Based Medicine video
V. Montori
View description
Victor Montori, MD, discusses, The End of Evidence Based Medicine.
11/16/2006 Picture from Evidence Based Medicine video
B. Potter
View description
Dr. Beth Potter, a local family medicine physician, will speak about how she uses EBM in her practice. She will give tips on how to find information quickly and where to find information for patient education vs. for your own education. Come learn about what EBM really means, and how to help your patients learn about their conditions, so they can better participate in their own health care.
11/08/2005 Picture from Herbal Medicine:  An Evidence-Based Perspective video
B. Barrett
View description

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Consumer Health video presentations



Consumer Health video presentations
from University of Wisconsin

Date
Presentation
08/06/2008 Picture from Health Literacy: Making Your Message More Understandable for All video
P. Smith

Picture from Personal Health Records: Introduction and Overview video
C. Arnott Smith, J. Everson, S. Heffron
View description
Catherine Arnott Smith gives an introduction and overview to personal health records. Jill Everson shares the MyHealtheVET project and Susan Heffron talks about Google Health.

Picture from Great Rivers Partners for Health-e People: Health Literacy Awareness in the Greater Midwest Region video
K. Crampton

Picture from Consumer Health / Patient Education Centers / Patient Libraries video

Picture from Badgerlink: A Free Source of Health Information video
L. Reale, L. Harmatuck

Picture from MedlinePlus Pearls video
B. Fay

Picture from Discover the Free Riches of NLM Resources video
M. Anderson

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Health Administration video presentations



Health Administration video presentations
from University of Wisconsin

Date
Presentation
04/20/2009 Picture from The Impact of Fatness on Disability Insurance Application by the Non-Elderly video
M. Schmeiser
02/20/2009 Picture from Understanding the Budget - Academic Staff video
R. Golden
02/19/2009 Picture from Accountable Care Organizations - A Path Forward to Quality and Savings video
E. Fisher
02/11/2009 Picture from Working with the Media video
L. Brunette
02/03/2009 Picture from Risk Assessment: Suicide and Violence video
R. Diamond
View description
Objectives of this presentation include: 1. Understand the frequency of suicide in a general medical practice 2. Identify the characteristics of those most at risk for suicide 3. Learn how to do a detailed behavioral assessment to rapidly assess suicide risk
12/17/2008 Picture from Averting Disaster: Prevention Strategies to Mitigate Escalating Situations video
S. Littlejohn
View description
The objectives of this presentation are to: 1) Understand that every act of violence in a healthcare setting has the potential to be a disaster 2) Recognize the emotional progression of escalating and de-escalating situations 3) Learn how your environment works for you or against you 4) Understand the impact of "role conflict" within the healthcare delivery system 5) Learn how to recognize and adjust to changes in your environment
10/22/2008 Picture from The Virginia Mason Production System: So Much Waste, So Little Time video
M. Iseman
View description
Marnee Iseman, shares how Lean principles can advance health care quality and efficiency.
08/25/2008 Picture from EMR Implementation: Doing it Right on a Budget video
J. Ahlstrom
07/07/2008 Picture from UWHC Compliance Program video
D. Weissburg
View description
"The Lawyer Among the Doctors"
05/05/2008 Picture from Optimal Patient Monitoring: What Is It and How Is It Done? video
C. Green
View description
In this presentation participants will learn: 1) Clinical characteristics requiring monitoring 2) How the use of technology, human endeavor and integration of clinical information result in optimal monitoring 3) False positive and false negative state during monitoring 4) The differences between clinical monitoring based upon provider anxiety, local practice patterns rather than upon scientifically established best practices
05/01/2008 Picture from Competing Approaches to Patient Safety:  The Handoff Problem video
R. Wears
View description
Concerns about the safety and quality of health care have created the 'patient safety movement' and led to a wide variety of activity. Although many may not have realized it, there is a great debate about the best strategy for effecting improvement that carries over into debates about the quality of 'evidence' and what constitutes scientific activity. This debate is rooted in underlying and often unrecognized differences in the philosophies of science and additionally is divided along social and professional lines, with healthcare researchers tending to assuming one side, and human factors professionals taking the other. We will explore these competing approaches, using the problems associated with handoffs in clinical work as an exemplar.
04/23/2008 Picture from Managing Risk: A Commitment to Compliance video
D. Weissburg
View description
In this presentation participants will learn: 1) What healthcare compliance means 2) Why it matters to physicians and healthcare organizations 3) What are the risks and current issues in the area of compliance 4) What are the ramifications of not being in compliance
04/04/2008 Picture from Improving Health Care Systems: A Focus on Safety and Reduction of Medical Errors video
C. Green

Picture from Disclosure: Communication with Patients video
M. Manering

Picture from The Legal Implications of Unanticipated Outcomes video
K. Wilson
01/28/2008 Picture from Marshfield Epidemiologic Study Area and the HMO Network: Growing Collaboration in Health Care Research video
R. Greenlee
12/06/2007 Picture from Do Hospitals Discharge Diagnosis Codes Accurately Capture Surgical Complications? The Case of Pediatric Adenotonsillectomy video
B. Edmonson
11/10/2007 Picture from A Human Factors Approach to Studying Medical Work video
M. Weinger
View description
Matthew Weinger, MD, provides an overview of 15 years of human factors research on point-of-care work processes in the medical domain, primarily in anesthesiology. Research projects to be discussed include field observations, device evaluations, and controlled studies in both real and simulated care environments. Methods for the conduct of task analysis, workload assessment, and event analysis will be emphasized.
09/13/2007 Picture from Academic Health Centers: Opportunities and Challenges video
S. Wartman
View description
Steven Wartman, MD, PhD, speaks on "Academic Health Centers: Opportunities and Challenges" at the Health Sciences Learning Center on September 13, 2007.
09/12/2007 Picture from Health Care Reform Initiatives: What Every Physician Needs to Know video
R. Formisano
View description
Roger Formisano, PhD, asks the question, with continued high cost trends, a Presidential election, more uninsured (fueled by cutbacks in employer sponsored plans), and Michael Moore's SiCKO...will significant health care reform find traction soon?
07/05/2007 Picture from HIPAA Protocol Review video
B. Delair
View description
Beth DeLair, RN, JD, speaks on "HIPAA Protocol Review" at the Transitional Clerkship Orientation on July 5, 2007.
06/27/2007 Picture from EMS Scope of Practice and Response Issues video
C. Etter
View description
EMS Scope of Practice and Response Issues are discussed at the Emergency Care and Trauma Symposium on June 27, 2007. The objectives of this presentation are: 1) Discuss scope of practice and administrative rules 2) Discuss EMS Procedures and Records and EMS Polices
05/10/2007 Picture from A Model of Private Health Care Provision in Inner-City Milwaukee video
M. Pruitt
View description
M. Eugene Pruitt, MD, an assistant professor at the Medical College of Wisconsin speaks on "A Model of Private Health Care Provision in Inner-City Milwaukee" at the Health Sciences Learning Center on May 10, 2007.
05/09/2007 Picture from Rethinking the Healthcare Model in Africa video
E. Darkoh
View description
Ernest Darkoh, MD, MPH, MBA, founder and chairman of Broadreach Healthcare speaks on "Rethinking the Healthcare Model in Africa" at the Health Sciences Learning Center on May 9, 2007.
05/03/2007 Picture from Human Factors in Medicine video
T. Best, J. Leff, S. Alper
View description
This video inlcudes presentations on the following: 1. Tom Best presents, "A Formative Evaluation of the UWHC Internal Medicine Outpatient Clinics - Summarizing Current Processes and Assessing Enhancement Opportunities." 2. Jared Leff presents, "Could This Be Delirium? An interdisciplinary approach to Improved Patient safety through interventions to prevent delirium." 3. Sam Alper presents, "Discussing Violations."
04/27/2007 Picture from Human Factors Engineering Translational Research in Healthcare Information Technology video
A. Schoofs Hundt
View description
Significant attention is being paid to translational research applied to health care – both clinically and administratively. In this lecture, Hundt presents an overview of translational research and the impact human factors engineering translational research can have in affecting change in health care, specifically applied to HIT. Experience from two HIT-related grants in which both prospective risk analysis and usability evaluation methods were incorporated will be discussed.
04/20/2007 Picture from Creating Resilient IT: How the Sign-Out Sheet Shows How Clinicians Make Healthcare Work video
C. Nemeth
View description
Healthcare is variable, contingent, complex, evanescent work domain. Systems such as information technology (IT) that are intended to support healthcare are often brittle; unable to adapt in the face of such change. Clinicians have developed subtle and well-tuned ways to match resources to variation in demand volume and quality. Their initiatives make it possible for healthcare teams to adapt and survive despite challenges…to be resilient. System developers can learn about how healthcare workers perform in such settings, but need appropriate methods to be effective and efficient. The study of cognitive artifacts can reveal meaningful information about the healthcare setting and how clinicians create resilience. Insights from such research are way to develop resilient systems and to improve healthcare safety.
04/17/2007 Picture from Surviving Your Deposition video
L. Wilson, L. Rutherford, N. Lynch
View description
The objectives of this presentation are to:
1. Discuss the deposition process and the physician's role
2. Provide tips on giving a deposition
3. Demonstrate dos and don'ts of giving a deposition
04/16/2007 Picture from Socio-Economic Status and Cancer Outcomes video
M. Coleman, M. Coleman
View description
Michel Coleman, MD, MSc, MFPHM, professor of epidemiology and vital statistics at the London School of Hygiene and Tropical Medicine, speaks on "Socio-Economic Status and Cancer Outcomes" at the Health Sciences Learning Center on April 16, 2007.
03/06/2007 Picture from Do You Know...Statutory Reporting and Other Regulatory Requirements for Physicians? video
B. Delair
View description
The objectives of this presentation are to:
1. Educate physicians on current statutory reporting requirements
2. Discuss other regulatory requirements that impact physician practice
3. Provide resources to assist with reporting and compliance requirements
02/26/2007 Picture from Spending Quality and the Paradox of Plenty video
E. Fisher
View description
Dr. Fisher is a professor of Medicine and Community and Family Medicine at the Dartmouth Medical School. He is also Director of Health Policy Research at Dartmouth's Center for the Evaluative Clinical Sciences. He spoke on Spending Quality and the Paradox of Plenty at the Health Sciences Learning Center on Febrary 26, 2007.
02/12/2007 Picture from Proxy Perspectives on Health-Related Quality of Life:  Applying Conceptual Framework to Prostate Cancer video
A. Pickard
View description
When assessing health-related quality of life (HRQL), proxy assessments are sometimes necessary. A conceptual framework has been developed that delineates between 2 proxy perspectives: elicitation from the patient perspective (proxy-patient), or from the proxy’s perspective (proxy-proxy). There is limited appreciation for this difference in the literature, and extent to which these perspectives differ systematically is unclear. The aim of this study was to determine if proxy assessment of HRQL differs according to perspective in prostate cancer, and to identify any factors that explain differences. In this presentation A. Simon Pickard will speak about this study. This event was sponsored by the University of Wisconsin School of Medicine and Public Health Department of Population Health Sciences.
02/02/2007 Picture from Applying a User Centered Quality Model to Healthcare Environments video
M. O'Neil
View description
Michael O'Neil, PhD, addresses the importance of a "user-centered" approach to design and management of healthcare environments. Users include patients, visitors and staff. This presentation asserts that assessment of healthcare facility quality must go beyond existing (important) measures of patient health outcomes, and include the impact of design of space on the quality of the user experience. A Six-Sigma based approach to implementing user-centered quality measures is then discussed. O'Neil's current research on Cancer Treatment Centers will also be briefly addressed.
11/27/2006 Picture from What Was the Clinton Health Plan? What Was Wrong With It? video
D. Kindig
View description
David Kindig, MD, PhD, Professor Emeritus of Population Health Sciences, University of Wisconsin-Madison, speaks on "What Was the Clinton Health Plan? What Was Wrong With It?".
11/20/2006 Picture from Efficiency and Quality in Health Care video
H. Fineberg
View description

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Methods and Strategies of Research



Methods and Strategies of Research
Copyright 2001 by Allyn & Bacon

Experimental Ablation

* Ablation involves the destruction of brain tissue followed by an assessment of subsequent changes in behavior
* Ablation techniques include
o Electrolytic lesions/Radio Frequency lesions
o Excitotoxic lesions (kainic acid)
o Neurochemical lesions (6-OHDA)
o Aspiration
o Knife cuts
* Distinction between functions and behaviors
* Brain lesion studies are complicated by the fact that all regions of the brain are interconnected



Stereotaxic Surgery

* A stereotaxic instrument holds the head in a fixed position
o The instrument has an arm that can move in 3 dimensions
o The surgeon can thus position an electrode or other device within a particular sub-cortical structure
* A stereotaxic atlas provides a series of drawings of brain structures
o Each page is a section of brain relative to a landmark on the skull (such as bregma)

Using a Stereotaxic Atlas to Target a Brain Lesion

Histological Techniques

* Histological techniques are used to verify the placement of a lesion within brain
o Perfuse (to remove blood from brain)
+ Remove brain
o Fix brain in formalin to solidify tissue and to prevent autolysis
+ Slice brain into thin sections (10-80 microns thick)
o Use stains to highlight selective neural elements
+ Myelin (Weil stain)
+ Cell body (cresyl violet: Nissl substance in cytoplasm)
+ Membrane (Golgi stain)

Defining Neural Connections

* Neurons in a given region send axonal outputs (efferents) to other brain regions and receive axonal inputs (afferents)
o Tracing efferent connections is done using anterograde labels that are taken up by the cell bodies and transported to axons
+ “Forward: toward axons from cell bodies”
+ Inject the lectin PHA-L into a nucleus, wait several days, process brain tissue.
+ Immunocytochemistry uses a radioactive antibody to PHA-L in order to identify cells containing PHA-L
o Tracing afferent connections is done using retrograde labeling
+ “Backwards: from axons to cell bodies”
+ e.g. fluorogold is a retrograde tracer

Anterograde Tracing
Visualizing a Living Human Brain
Human MRI (Normal)
Images courtesy of Dr. Nancy Andreason
Recording Neural Activity

* Axons conduct action potentials and neurotransmitters elicit postsynaptic potentials
* The electrical events of a discrete region can be recorded using glass microelectrodes (acute recording) or tungsten wire (chronic recording)
* Macroelectrodes record the summated electrical activity of large regions of brain
o Surface electrodes placed on human scalp are used to record brain activity (electroencephalogram: EEG)

Recording Synaptic Activity
Human Brain Imaging
Microdialysis
Microdialysis Probe Details
Artificial Stimulation of Brain
Localization of Neurotransmitters
Receptor Localization Techniques

Genetic Methods
* Genetic research methods seek to demonstrate the linkage between genes and behavior
* Twin studies examine the impact of varying degrees of genetic similarity on behavioral similarity
o Identical twins (MZ) share 100% of their genes while fraternal twins (DZ) share about 50% of their genes
o Concordance rate examines the likelihood of whether a twin shares a behavioral trait with the other twin
o A higher concordance rate for MZ twins relative to DZ twins suggests a genetic influence for that characteristic
* Adoption studies examine the similarity with regard to a trait for an adopted person compared to their adopted parents and their biological parents
* Targeted mutations involve the insertion of defective (knockout) genes into the chromosomes of mice

Methods and Strategies of Research.ppt

Original material copyright ©1997-2005 Addiction Research Unit. Original material presented here may be reprinted or used in any non-commercial form if proper credit is given to source and if original intent remains intact. All other material remains property of its copyright holder and is protected by international copyright laws.

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29 April 2009

How To Interpret Your Lab Tests



How To Interpret Your Lab Tests
Presentation by: Janice Price, M.Ed, RN
Swedish Medical Center


TESTS

* CBC: Complete Blood Count
* Serum Chemistries
* Liver Function/ Amylase
* Lipids: Blood Fats
* Immune System: CD4 & Viral Load

CBC: Complete Blood Count

* Red Blood Cells: RBC
* White Blood Cells:WBC
* Platelets: Plts
* Serum/Plasma

Blood Cell Types
Bone Marrow

* All Blood Cells made in bone marrow.
* Bone Marrow is the spongy centers of bones sometimes seen in cuts of meat

Stem Cells

* Stem cells are young cells
* All blood cells start as stem cells
* They get “drafted” as RBCs, WBCs or platelets depending on the body’s needs

Red Blood Cells

* Called erythrocytes
* “cytes” = cells
* Shaped like bagel with hole covered over
* Filled with hemoglobin that carries oxygen from the lungs to every cell in the body.

White Blood Cells

* WBCs are disease fighters
* Some make antibodies and some fight invaders directly
* Divided into categories depending on function and what they look like.

Types of White Cells

* Lymphocytes: B and T cells. Agranulocytes
* Granulocytes: polymorphonucleocoytes mostly neutrophils
* Monocytes: mature into macrophages (big eaters)

A macrophage attacking a bacteria with
a cellular extension called a pseudopod

Abbreviations

* RBC = Red Blood Cell
* WBC = White Blood Cell
* HCT = Hematocrit
* Hbg = Hemoglobin
* ANC = Absolute Neutrophil Count

TESTS OF IMMUNE FUNCTION

A human cell infected with a rhinovirus ruptures,
relasing millions of new viruses

A human T-helper cell is under
attack by HIV virus

Viral Load Tests

* PCR: Most common. Usually expressed has HIV-1 PCR in copies per milliliter. Roche Amplicor
* bDNA: values are different. Usually ½ of PCR value
* NASBA: nucleic acid sequence based amplification. Values are also different

UNDETECTABLE VIRAL LOAD DOES NOT MEAN NO VIRUS PRESENT

Remember: there are other places for virus to hide
Viral Load Expressed as Log
10 x = viral load

Genotype/Phenotype

Blood Types
Red Blood Cells: The Oxygen Carriers
T Killer cells attacking a cancer cell
White Blood Cells: Infection Fighters
Lymphocytes
Granulocytes
Neutrophils
Eosinophils
Basophils
Monocytes

Platelets: For Blood Clotting

Liver Function Tests (LFTs): LFTs include a number of markers that help determine liver status. These include ALT (SGPT), AST (SGOT), LDH, alkaline phosphatase and total bilirubin. Elevated liver enzymes are commonly caused by certain medications. Elevated enzyme levels can also be caused by liver disease such as hepatitis B or C, injuries, and tumors. Abnormal liver function test levels are common in 60-70% of people with HIV, but liver failure is unusual. High alkaline phosphatase levels along with normal bilirubin levels can show serious disease and are often seen in people with Mycobacterium avium Complex (MAC), cytomegalovirus (CMV), histoplasmosis, drug side effects or Kaposi's Sarcoma. Bilirubin, a product of dead red blood cells, is eliminated through the liver. High bilirubin levels in the blood can indicate hepatitis (associated with a yellow skin color), bile duct obstruction and other liver problems.

T-Cells train in Thymus. Involved in cell-mediated immunity: basically, hand-to-hand combat.
Many kinds: CD34, CD38, etc

Two of interest: CD4 and CD8 In HIV CD4 goes down and CD8 goes up.
* Nl CD4 about 600-1200/mm3.
* 2. Function important, but can’t tell from #’s
* 3. CD4 at type of lymphocyte. Absolute vs %
* Daily, hourly fluctuation.
* CD4:CD8 normally 2:1. Reverses in HIV as probable compensation.
* CD4 count usually lags behind VL, but good indicator of when to start treatment


Vaccines, illnesses, flare-ups of other viral illnesses like herpes
Test is sensitive to 0.5 log. Log is the power of 10 that will give you the VL

There are four basic blood types:

* Type A with A antigen on the red cells and anti-B antibodies in the plasma.
* Type B with B antigen on the red cells and anti-A antibodies in the plasma.
* Type AB with both A and B antigens on the red cells and neither anti-A nor anti-B in the plasma.
* Type O with no A or B antigens on the red cells and both anti-A and anti-B antibodies in the plasma.

If you are a Type A person, you do not carry antibodies against A markers. But you do have antibodies against Type B blood.
If you are a Type B person, you have antibodies against Type A cells.
If you are a Type O, you have antibodies against both Type A and B!

How To Interpret Your Lab Tests.ppt

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26 April 2009

Amyloid: Amyloidosis



Amyloid: Amyloidosis


Definition
----------------------
Amyloidosis is a clinical disorder caused by extracellular deposition of insoluble abnormal fibrils that injure tissue. The fibrils are formed by the aggregation of misfolded, normally soluble proteins. In humans, about 23 different unrelated proteins are known to form amyloid fibrils in vivo. All types of amyloid consist of a major fibrillar protein that defines the type of amyloid (approximately 90%) plus various minor components. Although each type of fibril may be associated with a distinct clinical picture, all share certain physical and pathologic properties, as follows:

* Amorphous eosinophilic appearance on light microscopy after hematoxylin and eosin staining
* Bright green fluorescence observed under polarized light after Congo red staining
* Regular fibrillar structure as observed by electron microscopy
* Beta pleated sheet structure as observed by x-ray diffraction
* Solubility in water and buffers of low ionic strength

* Amyloid

= insoluble fibrous protein aggregations that share specific structual traits
----------------------
* Amyloidosis

= abnormal deposition of amyloid proteins in tissues or organs ? cause disease

* Histological Definition
* extracellular proteinaceous deposits exhibiting cross-beta structure due to misfolding of unstable proteins
* stains with Congo-Red & seen under polarised light

* Biophysical Definition
* Any polypeptide which adopts a cross-beta polymerization (in vivo or in vitro)
* Some may fail congo red birefringence test
* Characterised by cross-beta quaterny structure


Recognition of Amyloid
Biochemical Nature of Amyloid
Biochemical Classification of Amyloid
Clinical Classification of Amyloidosis
Pathogenesis of Amyloid
Immunocytic Dyscrasias with Amyloid
Reactive Systemic Amyloidosis
Familial Amyloidosis
Familial Mediteranean Fever
Localised Amyloidosis

* Amyloid deposits limited to single organ or tissue.
* Deposits may produce grossly detachable nodular masses or be evident only on microscopic investigation.
* Nodular deposits of amyloid most often found in lung, larynx, skin, bladder, tongue & region around the eye.
* Frequently there are infiltrates of lymphocytes and plasma cells in the periphery of amyloid masses.
* Some cases consists of AL protein, and may therefore represent a localized form of immunocyte-derived amyloid.

Amyloid of Ageing
Clinical Effect on Spleen
Nodular Distribution
Clinical Effect on Kidney
Clinical Effect on Liver
Clinical Effect on GIT
Diagnosis & Prognosis

Amyloid: Amyloidosis.ppt

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24 April 2009

POCT and Laboratory Medicine / Accreditation



POCT and Laboratory Medicine / Accreditation

Diagnostic Accreditation Program
POCT and Lab Medicine
Presentation by: Arun K. Garg PhD, MD, FRCPC
Medical Director, Lab Medicine/Pathology
Fraser Health/RCH
330 E. Columbia Street
New Westminster

Point of Care Testing Accreditation (POTC)

Colin Semple ART
Accreditation & Research Development Officer
Diagnostic Accreditation Program of BC


Forces Changing Lab Medicine
Intitutional Testing

In vivo Point of Care Testing
* Institutional Acute Care

* Traditional Lab Services – ER, ICU, OR, Wards, Ambulance
* Physician office
* Ambulatory clinics
* Community clinics
* Pharmacies
* Long-term/Extended Care
* Home Care
* Ambulance
* Glucose meters
* Urinalysis
* Blood gases/electrolytes
* Coagulation studies
* Rapid Bacterial Strips
* Glycalated HbA1c
* Cardiac BioMarkers
* Hormones, Pregnancy testing
* Non blood skin reflectance - bilirubin

Some examples:

Cost
Therapeutic Turnaround Time
Medical Quality/Outcome
Forces of POCT
Acute Care and POCT
Chronic Care and POCT
Technology and POCT
Challenges of POCT
POCT and Non Lab Personnel
General Principles
Scientific/Technical
(Pre-Analytical – Post)
Fraser Health and POCT
References
Point of Care Testing-Definition
For accreditation purposes:
Accreditation Standards

2006-7 Draft standards developed
08/2007 Standards released for testing
03/2008 Revisions to POCT Standards
05/2008 Advisory Committee Approval
05/2008 Board Approval

Advisory Committees
POCT Accreditation Standards
On-site survey protocols (technical)
Talk to the laboratory staff involved in POCT oversight: overview, QC, PT
Speak with a nurse educator
POCT QC: selection, review
Laboratory medical leader’s role in POCT
Method/Instrument Selection/Validation
Roles and Responsibilities
Overall responsibility for POCT is assigned to the facility or regional laboratory leader or designate
The Laboratory Medical Leader defines the scope of POCT in consultation with the MAC, interdisciplinary practice groups or other appropriate groups.
Roles and Responsibilities
Accreditation surveys
“Rogue” POCT issues
Method and instrument selection, evaluation and validation
Roles and responsibilities
Training and competence testing
Documentation
Quality Control and Proficiency Testing
Instrument maintenance and monitoring
Reagents, chemicals and supplies
Results, records and reporting processes
Training/Orientation/Competence Testing
Documented Procedures
Quality Control
QC policies
Survey information
Proficiency Testing
Advisory Committees
Proficiency Testing
Mandated analytes:
Instruments and equipment
Reagents and Supplies
Recording of Results
Summary


AACC Annual Meeting
Washington DC
July 27-31, 2008

International POCT Symposium
Critical and Point of Care Testing: Managing Technology for the Benefit of all Populations
September 18-20, 2008 Barcelona, Spain


POCT and Laboratory Medicine/Accreditation.ppt

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23 April 2009

Heart Healthy Chocolate video



Heart Healthy Chocolate video

Chocolate is good for heart health as well as the palate. Mary Engler discusses the results of her research that show that chocolate and cocoa are rich, plant-derived sources of antioxidant flavonoids that promote beneficial effects to the cardiovascular system. App. one hour video

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22 April 2009

Seminar Videos



You need Realplayer to view these videos

Lessons Learned Implementing EHRs Abroad: Australia's HealthConnect
Walter Wieners, MA and Susan J. Hyatt, MBA
Seminar Video


Critical Issues in the Development and Implementation of a Health Record Banking System (Unabridged)
Jonathan Gold, MD Informatics fellow
Seminar Video


Towards Question Answering Systems for Evidence-Based Medicine
Dr.Jimmy Lin,Assistant Prof. University of Maryland-College of Information Studies
Seminar Video


A New Patient-centric and Sustainable Approach to Health Information Infrastructure
William A. Yasnoff, MD, PhD, FACMI
Seminar Video


The Texas Clinical Information Technology Evaluation (TEXCITE!) Project: A Quality Improvement Initiative to Enhance Information Systems in Texas Hospitals
Ruben Amarasingham, M.D
Seminar Video


Enabling Research of Patient Data and Information within the Context of New and Changing Compliance Requirements
Catherine Arnott Smith, PhD Assistant Professor - Syracuse University
Nancy McCall- Research Associate, JHMI
Seminar Video


Providing Research Informatics Support -- Some lessons learned supporting the
MIDAS family of NIH grants
Steve Naron, MS, MBA Executive Consultant and Architect, IBM Bethesda, MD
Seminar Video


Research Possibilities of Implementing an EMR in a Large Physician Group
Gary Noronha, MD Johns Hopkins Community Physicians
Seminar Video


Health Information System Development in a Developing Country
Ermias Seife, MD Director, Zewditu Hospital Addis Ababa, Ethiopia
Seminar Video

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15 April 2009

Academic Enhancement Presentations



Academic Enhancement Presentations from The University of Texas Health Science Center at San Antonio.

  1. [PPT]

    SuccessTypes And Effective Learning

    File Format: Microsoft Powerpoint - View as HTML
    1. SuccessTypes And Effective Learning. John W. Pelley, PhD. john.pelley@ttuhsc.edu. www.ttuhsc.edu/SOM/success/. 2. Getting In Touch With Your Thalamus ...
    som.uthscsa.edu/AcademicEnhancement/documents/SuccesstypesandeffectivelearningUMiss2008.ppt - Similar pages
  2. [PPT]

    Patient 1

    File Format: Microsoft Powerpoint - View as HTML
    Patient 1. CC: 5YOWFpresents with fever, marked weakness, pallor, bone pain, and bleeding from her nose; HPI: progressively increasing fatigability and ...
    som.uthscsa.edu/AcademicEnhancement/documents/USMLEcasepresentations.ppt -Similar pages
  3. [PPT]

    CV and Personal Statement

    File Format: Microsoft Powerpoint - View as HTML
    Agenda. Introductions; Time Lines; Curriculum Vitae (CV); Personal Statement; Evaluation. Background to Presentation. Dr. Nan Clare – Dean’s Office ...
    som.uthscsa.edu/AcademicEnhancement/documents/82207presentation.ppt - Similar pages
  4. [PPT]

    Biomedical Research: Opportunities and Benefits for Medical Students

    File Format: Microsoft Powerpoint - View as HTML
    Biomedical Research: Opportunities and Benefits for Medical Students. Robin L. Brey, MD. Associate Dean for Research. UTHSCSA. School of Medicine ...
    som.uthscsa.edu/AcademicEnhancement/documents/MedStudent1SummerandDistinction.ppt - Similar pages
  5. [PPT]

    Concept Mapping – Why, How, and When?

    File Format: Microsoft Powerpoint - View as HTML
    Concept Mapping – Why, How, and When? John W. Pelley, PhD. Texas Tech University School Of Medicine Lubbock, TX. www.ttuhsc.edu/SOM/success/ ...
    som.uthscsa.edu/AcademicEnhancement/documents/ConceptMappingwhenandhowUMiss2008.ppt - Similar pages
  6. [PPT]

    Learning in Groups

    File Format: Microsoft Powerpoint - View as HTML
    1. Learning in Groups. John W. Pelley, PhD. Texas Tech University School Of Medicine Lubbock, TX. www.ttuhsc.edu/SOM/success/ ...
    som.uthscsa.edu/AcademicEnhancement/documents/LearningingroupsUMiss2008.ppt -Similar pages
  7. [PPT]

    Week 2

    File Format: Microsoft Powerpoint - View as HTML
    Steven Katz, MSIV. Genetics Terms. Basic Terms (Review). Gene: A hereditary unit consisting of a sequence of DNA that occupies a specific location on a ...
    som.uthscsa.edu/AcademicEnhancement/documents/Step1Week2.ppt - Similar pages
  8. [PPT]

    USMLE STEP 1 Review: Week 3, Biochemistry

    File Format: Microsoft Powerpoint - View as HTML
    Chase Findley, MSIV. Vitamins, Fat Soluble, 94. Vitamins A, D, E, K. Absorption dependent on ileum and pancreas; Accumulate in body fat, more potential for ...
    som.uthscsa.edu/AcademicEnhancement/documents/week3.ppt - Similar pages
  9. [PPT]

    Board Review Week 1 Test

    File Format: Microsoft Powerpoint - View as HTML
    Board Review Week 1 Test. Good luck!! Question 1 of 40. (E) Opioids. (D) Barbiturates. (C) Amphetamines. (B) Cocaine. (A) Alcohol ...
    som.uthscsa.edu/AcademicEnhancement/documents/week1USMLEquestions.ppt -Similar pages
  10. [PPT]

    Slide 1

    File Format: Microsoft Powerpoint - View as HTML
    Board Review Week 3 Test. Good luck!! (E) Neocortex. (D) Cerebral motor cortex. (C) Cerebral frontal lobes. (B) Amygdaloid nuclei and lumbar system ...
    som.uthscsa.edu/AcademicEnhancement/documents/week3USMLEquestions.ppt -Similar pages
  11. [PPT]

    Rapid review: first aid

    File Format: Microsoft Powerpoint - View as HTML
    Rapid review: first aid. Often precedes squamous cell carcinoma. Actinic keratosis. Primary adrenocortical deficiency. Addison’s disease ...
    som.uthscsa.edu/AcademicEnhancement/documents/Rapidreviewboards.ppt - Similar pages
  12. [PPT]

    Week 7 USMLE Step 1 Review: Biostatistics and Nutrition

    File Format: Microsoft Powerpoint - View as HTML
    Steven Katz MSIV. PART 1: BIOSTATISTICS. Terms: Independent variable: values that are controlled or selected by the person experimenting to determine its ...
    som.uthscsa.edu/AcademicEnhancement/documents/week7ppt.ppt - Similar pages
  13. [PPT]

    USMLE STEP I Review Week 6: Renal and Hematology Physiology

    File Format: Microsoft Powerpoint - View as HTML
    Steven Katz, MSIV. Part 1: Hematology and Oncology (p.326-347). Blood Cell Differentiation. Heme Terms (p. 327). Erythrocyte: anucleate, biconcave cell with ...
    som.uthscsa.edu/AcademicEnhancement/documents/week6ppt.ppt - Similar pages
  14. [PPT]

    som.uthscsa.edu/ClinicalSkillCenter/documents/Clin...

    File Format: Microsoft Powerpoint - View as HTML
    CLINICAL SKILLS CENTER.
    Similar pages
  15. [PPT]

    Slide 1

    File Format: Microsoft Powerpoint - View as HTML
    Board Review Week 2 Test. Good luck!! Question 1 of 40. (E) the seminiferous tubules. (D) the urethral opening. (C) the cervix. (B) the ovary ...
    som.uthscsa.edu/AcademicEnhancement/documents/week2USMLEquestions.ppt -Similar pages

Read more...
All links posted here are collected from various websites. No video or powerpoint files are uploaded on this blog. If you are the original author and do not wish to display your content on this blog please Email me anandkumarreddy at gmail dot com I will remove it. The contents of this blog are meant for educational purpose and not for commercial use. If you use any content give due credit to the original author.

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