Onchocerciasis / River Blindness Lecture notes and 707 free access articles
Onchocerciasis also known as river blindness and Robles' disease, is a parasitic disease caused by infection by Onchocerca volvulus, a nematode. Onchocerciasis is the world's second-leading infectious cause of blindness.
River Blindness/ Onchocerciasis
Lawrence O. Gostin
http://www.pitt.edu/
Vector control
http://www.striepen.uga.edu/
CHALLENGING HEALTH PROBLEMS -WESTERN SUDAN
SULAIMAN, S. M.
http://www.pitt.edu
Blindness
Ines Serrano MD, Evan Waxman MD PHD
http://www.pitt.edu/
Ophthalmic Epidemiology
Michael B. Gorin, M.D. Ph.D.
http://www.pitt.edu/
Tropical Ophthalmology
Dr. Steve Waller
http://www.pitt.edu/
http://www.pitt.edu/
onchocerciasis
http://www.striepen.uga.edu/
River Blindness
http://courses.bio.unc.edu/
A Brief overview of Vector-Borne IIlness
Jill Gallin
http://www.columbia.edu/
Black-Flies, Biting Midges and Sandflies
http://www.uwyo.edu/
DNA barcoding for disease vectors
Daniel Adjei Boakye
http://barcoding.si.edu/
Lymphatic Filariasis / Elephantiasis Loiasis Onchocerciasis (river blindness)
Wafa Menawi
http://elearning.najah.edu/
Climate Change and Vector-Borne Disease
Durland Fish, Ph.D.
http://publichealth.yale.edu/
Use of GIS for Decision Making in the Onchocerciasis Control Program in West Africa
Alexander Coles
http://www.payson.tulane.edu/
Towards an ontology of vector-borne diseases
http://ontology.buffalo.edu/
The World of Parasites: A brief overview of the gruesome lives of parasites
Maya Merritt and Mindy Johnson
http://cipm.ncsu.edu
Neglected Tropical Diseases
Amy Kapczynski
http://gspp.berkeley.edu/
707 Published scholarly articles free access
River Blindness/ Onchocerciasis
Lawrence O. Gostin
http://www.pitt.edu/
Vector control
http://www.striepen.uga.edu/
CHALLENGING HEALTH PROBLEMS -WESTERN SUDAN
SULAIMAN, S. M.
http://www.pitt.edu
Blindness
Ines Serrano MD, Evan Waxman MD PHD
http://www.pitt.edu/
Ophthalmic Epidemiology
Michael B. Gorin, M.D. Ph.D.
http://www.pitt.edu/
Tropical Ophthalmology
Dr. Steve Waller
http://www.pitt.edu/
http://www.pitt.edu/
onchocerciasis
http://www.striepen.uga.edu/
River Blindness
http://courses.bio.unc.edu/
A Brief overview of Vector-Borne IIlness
Jill Gallin
http://www.columbia.edu/
Black-Flies, Biting Midges and Sandflies
http://www.uwyo.edu/
DNA barcoding for disease vectors
Daniel Adjei Boakye
http://barcoding.si.edu/
Lymphatic Filariasis / Elephantiasis Loiasis Onchocerciasis (river blindness)
Wafa Menawi
http://elearning.najah.edu/
Climate Change and Vector-Borne Disease
Durland Fish, Ph.D.
http://publichealth.yale.edu/
Use of GIS for Decision Making in the Onchocerciasis Control Program in West Africa
Alexander Coles
http://www.payson.tulane.edu/
Towards an ontology of vector-borne diseases
http://ontology.buffalo.edu/
The World of Parasites: A brief overview of the gruesome lives of parasites
Maya Merritt and Mindy Johnson
http://cipm.ncsu.edu
Neglected Tropical Diseases
Amy Kapczynski
http://gspp.berkeley.edu/
707 Published scholarly articles free access
- Oligonucleotide Based Magnetic Bead Capture of Onchocerca volvulus DNA for PCR Pool Screening of Vector Black Flies.
- [Evaluation on implementation of the African programme for onchocerciasis control in Nigeria].
- Autophagy regulates Wolbachia populations across diverse symbiotic associations.
- Empowering communities in combating river blindness and the role of NGOs: case studies from Cameroon, Mali, Nigeria and Uganda.
- A research agenda for helminth diseases of humans: the problem of helminthiases.
- A research agenda for helminth diseases of humans: intervention for control and elimination.
- Human ocular onchocerciasis: further evidence on the zoonotic role of Onchocerca lupi.
- Density-dependent mortality of the human host in onchocerciasis: relationships between microfilarial load and excess mortality.
- Implementing preventive chemotherapy through an integrated National Neglected Tropical Disease Control Program in Mali.
- Long term impact of large scale community-directed delivery of doxycycline for the treatment of onchocerciasis.
- Immunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesis.
- Significant association between epilepsy and presence of onchocercal nodules: case-control study in Cameroon.
- Impact of long-term treatment of onchocerciasis with ivermectin in Kaduna State, Nigeria: first evidence of the potential for elimination in the operational area of the African Programme for Onchocerciasis Control.
- Validation of the rapid assessment procedure for loiasis (RAPLOA) in the democratic republic of Congo.
- Multiple filarial species microfilaraemia: a comparative study of areas with endemic and sporadic onchocerciasis.
- Nodding syndrome - South Sudan, 2011.
- Prevalence of onchocerciasis in the Fundong Health District, Cameroon after 6 years of continuous community-directed treatment with ivermectin.
- An insight into the sialome of Simulium guianense (DIPTERA:SIMulIIDAE), the main vector of River Blindness Disease in Brazil.
- Neglected tropical diseases and the millennium development goals: why the "other diseases" matter: reality versus rhetoric.
- African Programme for Onchocerciasis Control: meeting of national task forces, September 2011.
- Ocular onchocerciasis: current management and future prospects.
- The Global Programme to Eliminate Lymphatic Filariasis: History and achievements with special reference to annual single-dose treatment with diethylcarbamazine in Samoa and Fiji.
- Onchocerciasis in the Americas: from arrival to (near) elimination.
- InterAmerican Conference on Onchocerciasis, 2010: progress towards eliminating river blindness in the WHO Region of the Americas.
- InterAmerican Conference on Onchocerciasis, 2010: progress towards eliminating river blindness in the WHO Region of the Americas.
- Lymphatic filariasis in the Democratic Republic of Congo; micro-stratification overlap mapping (MOM) as a prerequisite for control and surveillance.
- Rapid molecular assays for specific detection and quantitation of Loa loa microfilaremia.
- Excretion of moxidectin into breast milk and pharmacokinetics in healthy lactating women.
- Meeting of the International Task Force for Disease Eradication, April 2011.
- Compliance with eight years of annual ivermectin treatment of onchocerciasis in Cameroon and Nigeria.
- The geographic distribution of Loa loa in Africa: results of large-scale implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA).
- River blindness: an old disease on the brink of elimination and control.
- Drawing and interpreting data: Children's impressions of onchocerciasis and community-directed treatment with ivermectin (CDTI) in four onchocerciasis endemic countries in Africa.
- Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.
- Polymerase chain reaction pool screening used to compare prevalence of infective black flies in two onchocerciasis foci in northern Sudan.
- Phenotypic evidence of emerging ivermectin resistance in Onchocerca volvulus.
- Zoonotic helminths affecting the human eye.
- Where would I be without ivermectin? Capturing the benefits of community-directed treatment with ivermectin in Africa.
- Elimination of neglected diseases in latin america and the Caribbean: a mapping of selected diseases.
- Ivermectin, 'wonder drug' from Japan: the human use perspective.
- Information for onchocerciasis control.
- The applications of model-based geostatistics in helminth epidemiology and control.
- Onchocerciasis.
- Description of the parasite Wucheria bancrofti microfilariae identified in follicular fluid following transvaginal oocyte retrieval.
- Gender-associated genes in filarial nematodes are important for reproduction and potential intervention targets.
- Primary motives for demand of ivermectin drug in mass distribution programmes to control onchocerciasis.
- Tropical Diseases Targeted for Elimination: Chagas Disease, Lymphatic Filariasis, Onchocerciasis, and Leprosy.
- Skin Diseases.
- Case report: First evidence of human zoonotic infection by Onchocerca lupi (Spirurida, Onchocercidae).
- Integrated implementation of programs targeting neglected tropical diseases through preventive chemotherapy: proving the feasibility at national scale.
- Does mass drug administration for the integrated treatment of neglected tropical diseases really work? Assessing evidence for the control of schistosomiasis and soil-transmitted helminths in Uganda.
- Social sciences research in neglected tropical diseases 2: A bibliographic analysis.
- Perception and attitude of people toward onchocerciasis (river blindness) in South Western Nigeria.
- A worm's best friend: recruitment of neutrophils by Wolbachia confounds eosinophil degranulation against the filarial nematode Onchocerca ochengi.
- Mass drug administration of ivermectin in south-eastern Senegal reduces the survivorship of wild-caught, blood fed malaria vectors.
- Geographical distribution of intestinal schistosomiasis and soil-transmitted helminthiasis and preventive chemotherapy strategies in Sierra Leone.
- Emergence of Onchocerca volvulus from skin mimicking Dracunculiasis medinensis.
- Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity.
- Control of neglected tropical diseases needs a long-term commitment.
- Selective activity of extracts of Margaritaria discoidea and Homalium africanum on Onchocerca ochengi.
- Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis.
- Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes.
- Biting behaviour of Simulium damnosum complex and Onchocerca volvulus infection along the Osun River, Southwest Nigeria.
- Hyperendemicity of onchocerciasis in ovia northeast local government area, edo state, Nigeria.
- Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation.
- Onchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.
- Effects of annual mass treatment with ivermectin for onchocerciasis on the prevalence of intestinal helminths.
- The Onchocerca volvulus cysteine proteinase inhibitor, Ov-CPI-2, is a target of protective antibody response that increases with age.
- The Wolbachia endosymbiont as an anti-filarial nematode target.
- Report from the 2009 Inter-American Conference on Onchocerciasis: progress towards eliminating river blindness in the Region of the Americas.
- Neglected tropical diseases outside the tropics.
- The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells.
- Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?
- Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis.
- Community-directed interventions for priority health problems in Africa: results of a multicountry study.
- How to (or not to) integrate vertical programmes for the control of major neglected tropical diseases in sub-Saharan Africa.
- Analysis of the mdr-1 gene in patients co-infected with Onchocerca volvulus and Loa loa who experienced a post-ivermectin serious adverse event.
- Interruption of transmission of Onchocerca volvulus in the Oaxaca focus, Mexico.
- Lack of active Onchocerca volvulus transmission in the northern Chiapas focus of Mexico.
- The effect of oral anthelmintics on the survivorship and re-feeding frequency of anthropophilic mosquito disease vectors.
- Factors associated with compliance with community directed treatment with ivermectin for onchocerciasis control in Southwestern Ethiopia.
- Immunohistology of ectopic secondary lymph follicles in subcutaneous nodules from patients with hyperreactive onchocerciasis (sowda).
- Onchocerciasis in the upper imo river basin, Nigeria: prevalence and comparative study of waist and shoulder snips from mesoendemic communities.
- Anticoagulant activity in salivary gland homogenates of Thyrsopelma guianense (Diptera: Simuliidae), the primary vector of onchocerciasis in the Brazilian Amazon.
- Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.
- Does onchocerciasis transmission take place in hypoendemic areas? a study from the North Region of Cameroon.
- A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia.
- Immunohistological studies on neoplasms of female and male Onchocerca volvulus: filarial origin and absence of Wolbachia from tumor cells.
- Reframing critical needs in vector biology and management of vector-borne disease.
- Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
- Considerations for the design and conduct of a pharmacovigilance study involving mass drug administration in a resource-constrained setting.
- African Programme for Onchocerciasis Control - report of the sixth meeting of national task forces, October 2009.
- Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule.
- Monitoring ivermectin distributors involved in integrated health care services through community-directed interventions--a comparison of Cameroon and Uganda experiences over a period of three years (2004-2006).
- [River blindness can be eliminated].
- Preliminary study on temporal variations in biting activity of Simulium damnosum s.l. in Abeokuta North LGA, Ogun State Nigeria.
- Immunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposure.
- Neglected tropical diseases in Brazil.
- Picture this...Onchocerciasis.
- Identifying sub-optimal responses to ivermectin in the treatment of River Blindness.
- Onchocerciasis (river blindness). Report from the eighteenth InterAmerican Conference on Onchocerciasis, November 2008.
- Onchocerciasis: elimination is feasible.
- Newly acquired Onchocerca volvulus filariae after doxycycline treatment.
- Community-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon.
- Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden.
- Exposure of seasonal migrant workers to Onchocerca volvulus on coffee plantations in Guatemala.
- Laboratory diagnosis of infections due to blood and tissue parasites.
- Prospects for the control of neglected tropical diseases by mass drug administration.
- Feasibility of onchocerciasis elimination with ivermectin treatment in endemic foci in Africa: first evidence from studies in Mali and Senegal.
- The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target.
- Worrisome outbreak of river blindness in northern Uganda.
- Epilepsy in onchocerciasis endemic areas: systematic review and meta-analysis of population-based surveys.
- Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa.
- A four-antigen mixture for rapid assessment of Onchocerca volvulus infection.
- Nigeria's war on terror: fighting dracunculiasis, onchocerciasis, lymphatic filariasis, and schistosomiasis at the grassroots.
- Cardiocladius oliffi (Diptera: Chironomidae) as a potential biological control agent against Simulium squamosum (Diptera: Simuliidae).
- Successful interruption of transmission of Onchocerca volvulus in the Escuintla-Guatemala focus, Guatemala.
- Gamma interferon and interleukin-1 receptor 1 regulate neutrophil recruitment to the corneal stroma in a murine model of Onchocerca volvulus keratitis.
- Onchocerciasis Control: Vision for the Future from a Ghanian perspective.
- Immunoglobulin kappa chain locus on chromosome 2p12 and onchocerciasis.
- Onchocerciasis and trachoma control: what has changed in the past two decades?
- Zoonotic filariasis in the Arabian Peninsula: autochthonous onchocerciasis and dirofilariasis.
- Onchocerciasis, cysticercosis, and epilepsy.
- The global programme to eliminate lymphatic filariasis: health impact after 8 years.
- The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination.
- Impact of long-term treatment with ivermectin on the prevalence and intensity of soil-transmitted helminth infections.
- Transmission dynamics of Simulium damnosum in rural communities of Akwa Ibom State, Nigeria.
- African Programme for Onchocerciasis Control--report on task force meeting, July 2008.
- Rapid suppression of Onchocerca volvulus transmission in two communities of the Southern Chiapas focus, Mexico, achieved by quarterly treatments with Mectizan.
- Engaging the community: an interview with Uche Amazigo by Brown Hannah.
- Report from the Inter-American Conference on Onchocerciasis, November 2007.
- After a decade of annual dose mass ivermectin treatment in Cameroon and Uganda, onchocerciasis transmission continues.
- UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle.
- Human genetic resistance to Onchocerca volvulus: evidence for linkage to chromosome 2p from an autosome-wide scan.
- Filarioid nematodes in cattle, sheep and horses in Finland.
- Sir Nicholas Harold Lloyd Ridley: 10 July 1906 - 25 May 2001.
- Of mice, cattle, and humans: the immunology and treatment of river blindness.
- Operational lessons from 20 years of the Mectizan Donation Program for the control of onchocerciasis.
- Population dynamics of onchocerca volvulus microfilariae in human host after six years of drug control.
- Encephalopathy after ivermectin treatment in a patient infected with Loa loa and Plasmodium spp.
- A Global Fund to Fight Neglected Tropical Diseases: is the G8 Hokkaido Toyako 2008 Summit ready?
- A novel, helminth-derived immunostimulant enhances human recall responses to hepatitis C virus and tetanus toxoid and is dependent on CD56+ cells for its action.
- Could neurocysticercosis be the cause of "onchocerciasis-associated" epileptic seizures?
- Triple co-administration of ivermectin, albendazole and praziquantel in zanzibar: a safety study.
- Onchocerca jakutensis filariasis in humans.
- Evidence for suppression of Onchocerca volvulus transmission in the Oaxaca focus in Mexico.
- Fc gamma RIIa (CD32) polymorphism and onchocercal skin disease: implications for the development of severe reactive onchodermatitis (ROD).
- Contribution of migrant coffee labourers infected with Onchocerca volvulus to the maintenance of the microfilarial reservoir in an ivermectin-treated area of Mexico.
- Oncocerchiasis: an imported case from the tropics.
- Eliminating lymphatic filariasis, onchocerciasis, and schistosomiasis from the americas: breaking a historical legacy of slavery.
- Measuring the burden of neglected tropical diseases: the global burden of disease framework.
- Epidemiology and psycho-social aspects of onchocercal skin diseases in northeastern Nigeria.
- Monitoring lymphatic filariasis interventions: Adult mosquito sampling, and improved PCR - based pool screening method for Wuchereria bancrofti infection in Anopheles mosquitoes.
- Taxonomy and inventory of the cytospecies and cytotypes of the Simulium damnosum complex (Diptera: Simuliidae) in relation to onchocerciasis.
- Mining predicted essential genes of Brugia malayi for nematode drug targets.
- Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.
- A new voice for the poor.
- Ivermectin resistance in Onchocerca volvulus: toward a genetic basis.
- The future of onchocerciasis control in Africa.
- Genetic selection of low fertile Onchocerca volvulus by ivermectin treatment.
- No depletion of Wolbachia from Onchocerca volvulus after a short course of rifampin and/or azithromycin.
- Persistent and untreated tropical infectious diseases among Sudanese refugees in the United States.
- Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis.
- Onchocerciasis (river blindness). Report from the sixteenth InterAmerican Conference on Onchocerciasis, Antigua Guatemala, Guatemala.
- Elimination of Onchocercia volvulus transmission in the Santa Rosa focus of Guatemala.
- WHO-based tropical disease research programme to focus on emerging diseases.
- Meeting of the International Task Force for Disease Eradication--11 January 2007.
- Impact of long-term treatment of onchocerciasis with ivermectin in Ecuador: potential for elimination of infection.
- Mansonella streptocerca: another filarial worm in the skin in Western Uganda.
- Community selection of ivermectin distributors.
- Vision 2020: update on onchocerciasis.
- Onchocerciasis: impact of interventions.
- The maintenance and repair of ophthalmic surgical instruments: training at the eye clinic.
- Detection of Onchocerca volvulus (Nematoda: Onchocercidae) infection in vectors from Amazonian Brazil following mass Mectizan distribution.
- Prevalence and causes of blindness and visual impairment in Limbe urban area, South West Province, Cameroon.
- Onchocerca volvulus-specific antibody and cytokine responses in onchocerciasis patients after 16 years of repeated ivermectin therapy.
- Feasibility of measuring compliance to annual ivermectin treatment in the African Programme for Onchocerciasis Control.
- Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline.
- Evaluation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in Central Africa.
- Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM.
- The reliability of anterior segment lesions as indicators of onchocercal eye disease in Guatemala.
- Recent updates on onchocerciasis: diagnosis and treatment.
- Modeling targeted ivermectin treatment for controlling river blindness.
- [Vector capacities of Similium damsnosum s.l and risk for Onchocerca volvulus transmission in Inga (Democratic Republic of Congo)].
- Successful integration of insecticide-treated bed net distribution with mass drug administration in Central Nigeria.
- The Mectizan Donation Program - highlights from 2005.
- River blindness: a success story under threat?
- Integration of mass drug administration programmes in Nigeria: The challenge of schistosomiasis.
- Onchocerciasis (river blindness). Report from the fifteenth InterAmerican Conference on Onchocerciasis, Caracas, Venezuela.
- Reduction in the prevalence and intensity of infection in Onchocerca volvulus microfilariae according to ethnicity and community after 8 years of ivermectin treatment on the island of Bioko, Equatorial Guinea.
- Cytogenetic and PCR-based identification of S. damnosum "Nkusi J" as the anthropophilic blackfly in the Uluguru onchocerciasis focus in Tanzania.
- Onchocercosis of an intervertebral joint capsule causing cervical vertebral stenotic myelopathy in a horse.
- Field applicability of a rapid-format anti-Ov-16 antibody test for the assessment of onchocerciasis control measures in regions of endemicity.
- Perception of blindness and blinding eye conditions in rural communities.
- Large-scale entomologic assessment of Onchocerca volvulus transmission by poolscreen PCR in Mexico.
- [Onchocerciasis: one way of living].
- [Parasitic etiology of blood hypereosinophilia].
- Consequences of vector behavior in epidemiology of onchocerciasis on the Firestone Rubber Plantation in Liberia.
- Important experimental parameters for determining infection rates in arthropod vectors using pool screening approaches.
- Global epidemiology, ecology and control of soil-transmitted helminth infections.
- Vision 2020 and prevention of blindness: is it relevant or achievable in the modern era?
- Prevalence and causes of blindness and visual impairment in Muyuka: a rural health district in South West Province, Cameroon.
- In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination.
- The promise of wolbachia-targeted chemotherapy as a public health intervention for lymphatic filariasis and onchocerciasis.
- Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88.
- Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin.
- Case records of the Massachusetts General Hospital. Case 39-2005. A 63-year-old woman with a positive serologic test for syphilis and persistent eosinophilia.
- Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease.
- Short report: impact of ivermectin community-level treatments on elimination of adult Onchocerca volvulus when individuals receive multiple treatments per year.
- Protective immunity to the larval stages of onchocerca volvulus is dependent on Toll-like receptor 4.
- Chemokines in onchocerciasis patients after a single dose of ivermectin.
- Human infection patterns and heterogeneous exposure in river blindness.
- Short communication: impact of long-term (14 years) bi-annual ivermectin treatment on Wuchereria bancrofti microfilaraemia.
- Antibiotic chemotherapy of onchocerciasis: in a bovine model, killing of adult parasites requires a sustained depletion of endosymbiotic bacteria (Wolbachia species).
- Status of forest onchocerciasis in the Lower Cross River basin, Nigeria: entomologic profile after five years of ivermectin intervention.
- Repeated high doses of avermectins cause prolonged sterilisation, but do not kill, Onchocerca ochengi adult worms in African cattle.
- Onchocerciasis diagnosed in Italy.
- Mass ivermectin treatment for onchocerciasis: lack of evidence for collateral impact on transmission of Wuchereria bancrofti in areas of co-endemicity.
- Onchocerciasis: a potential risk factor for glaucoma.
- The order is rapidly fadin'.
- Economic impact of dengue fever/dengue hemorrhagic fever in Thailand at the family and population levels.
- Predictors of compliance with community-directed ivermectin treatment in Uganda: quantitative results.
- Effect of repeated community-based ivermectin treatment on the intensity of onchocerciasis in Nigeria.
- Combined Utilisation of Rapid Assessment Procedures for Loiasis (RAPLOA) and Onchocerciasis (REA) in Rain forest Villages of Cameroon.
- Community-directed interventions strategy enhances efficient and effective integration of health care delivery and development activities in rural disadvantaged communities of Uganda.
- Frequent detection of worm movements in onchocercal nodules by ultrasonography.
- Development and evaluation of an antigen detection dipstick assay for the diagnosis of human onchocerciasis.
- Whither onchocerciasis control in Africa?
- Prevalence of antibodies to onchocerca volvulus in residents of Oaxaca, Mexico, treated for 10 years with ivermectin.
- Structure of the major cytosolic glutathione S-transferase from the parasitic nematode Onchocerca volvulus.
- Prevalence of parasitic diseases among nomadic Fulanis of south-eastern Nigeria.
- Anti-desmoglein-1 antibodies in onchocerciasis, leishmaniasis and Chagas disease suggest a possible etiological link to Fogo selvagem.
- Relevance of ex vivo blood lymphocyte assay for in vivo lymphocyte function.
- The effects of long-term community level treatment with ivermectin (Mectizan) on adult Onchocerca volvulus in Latin America.
- Blackflies (Diptera: Simuliidae) of Southern Guyana with keys for the identification of adults and pupae--a review.
- Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness).
- The role of mathematical modeling in evidence-based malaria control.
- Additional health and development activities for community-directed distributors of ivermectin: threat or opportunity for onchocerciasis control?
- The impact of ivermectin treatment alone and when in parallel with Simulium neavei elimination on onchocerciasis in Uganda.
- Mapping the distribution of Loa loa in Cameroon in support of the African Programme for Onchocerciasis Control.
- Two new cytoforms of the Simulium damnosum complex (Diptera: Simuliidae) from Malawi and Tanzania and potential onchocerciasis vectors.
- Genetic heterogeneity in Loa loa parasites from southern Cameroon: A preliminary study.
- The major surface protein of Wolbachia endosymbionts in filarial nematodes elicits immune responses through TLR2 and TLR4.
- A longitudinal study of impact of repeated mass ivermectin treatment on clinical manifestations of onchocerciasis in Imo State, Nigeria.
- Incidence of blindness during the Onchocerciasis control programme in western Africa, 1971-2002.
- Impact of ivermectin on illness and disability associated with onchocerciasis.
- The delivery of ivermectin (Mectizan).
- Economic evaluation of Mectizan distribution.
- Mectizan Donation Program: evaluation of a public-private partnership.
- Eliminating onchocerciasis as a public health problem.
- Research for control: the onchocerciasis experience.
- Combating tropical infectious diseases: report of the Disease Control Priorities in Developing Countries Project.
- Programmatic and Communication Issues in Relation to Serious Adverse Events Following Ivermectin Treatment in areas Co-endemic for Onchocerciasis and Loiasis.
- A Framework for Decision-Making for Mass Distribution of Mectizan(R) in Areas Endemic for Loa loa.
- Ivermectin: does P-glycoprotein play a role in neurotoxicity?
- Loa loa encephalopathy temporally related to ivermectin administration reported from onchocerciasis mass treatment programs from 1989 to 2001: implications for the future.
- Clinical picture and outcome of Serious Adverse Events in the treatment of Onchocerciasis.
- Possible pathogenic pathways in the adverse clinical events seen following ivermectin administration to onchocerciasis patients.
- Clinical picture, epidemiology and outcome of Loa-associated serious adverse events related to mass ivermectin treatment of onchocerciasis in Cameroon.
- Serious adverse events following treatment with ivermectin for onchocerciasis control: a review of reported cases.
- Report of a Scientific Working Group on Serious Adverse Events following Mectizan(R) treatment of onchocerciasis in Loa loa endemic areas.
- Overview: Report of a Scientific Working Group on Serious Adverse Events following Mectizan(R) treatment of onchocerciasis in Loa loa endemic areas.
- Polymerase chain reaction monitoring of transmission of Onchocerca volvulus in two endemic states in Mexico.
- [Retinal hemorrhages after ivermectin treatment for onchocerciasis in a patient with Loa loa microfilaremia].
- Adverse reactions to ivermectin treatment in Simulium neavei-transmitted onchocerciasis.
- Global change and human vulnerability to vector-borne diseases.
- Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis.
- Stemming the tide of river blindness: the early years of ivermectin.
- Integrated community-directed treatment for the control of onchocerciasis, schistosomiasis and intestinal helminths infections in Uganda: advantages and disadvantages.
- Treatment of co-infection with bancroftian filariasis and onchocerciasis: a safety and efficacy study of albendazole with ivermectin compared to treatment of single infection with bancroftian filariasis.
- Progressive vision loss in a man from Cameroon.
- Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis.
- Prediction of community prevalence of human onchocerciasis in the Amazonian onchocerciasis focus: Bayesian approach.
- Variation in incidence of serious adverse events after onchocerciasis treatment with ivermectin in areas of Cameroon co-endemic for loiasis.
- Onchocerciasis (river blindness).
- Onchocerciasis among Ethiopian immigrants in Israel.
- Obligatory symbiotic Wolbachia endobacteria are absent from Loa loa.
- Product R&D for neglected diseases. Twenty-seven years of WHO/TDR experiences with public-private partnerships.
- Impact of ivermectin on onchocerciasis transmission: assessing the empirical evidence that repeated ivermectin mass treatments may lead to elimination/eradication in West-Africa.
- [Onchocerciasis].
- Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1.
- Entomological evaluation by pool screen polymerase chain reaction of Onchocerca volvulus transmission in Ecuador following mass Mectizan distribution.
- Final report of the Conference on the eradicability of Onchocerciasis.
- Immune responses directed against microfilariae correlate with severity of clinical onchodermatitis and treatment history.
- Local knowledge and attitudes about onchocerciasis in Oji-River local government area of Enugu State, Nigeria.
- Onchocerciasis.
- Profile of eye lesions and vision loss: a cross-sectional study in Lusambo, a forest-savanna area hyperendemic for onchocerciasis in the Democratic Republic of Congo.
- Transmission intensity and the patterns of Onchocerca volvulus infection in human communities.
- Serum immunoglobulin G4 antibodies to the recombinant antigen, Ll-SXP-1, are highly specific for Loa loa infection.
- Rapid assessment method for prevalence and intensity of Loa loa infection.
- Onchodermal skin disease in a hyperendemic onchocerciasis focus in western Uganda.
- Lymphatic filariasis elimination and schistosomiasis control in combination with onchocerciasis control in Nigeria.
- Association of transient dermal mastocytosis and elevated plasma tryptase levels with development of adverse reactions after treatment of onchocerciasis with ivermectin.
- History of human parasitology.
- Validity of nodule palpation in a Simulium neavei-transmitted onchocerciasis area in Uganda.
- Human onchocerciasis in Brazil: an overview.
- Comparison between the skin snip test and simple dot blot assay as potential rapid assessment tools for Onchocerciasis in the postcontrol era in Ghana.
- IL-4 and IL-13 regulation of ICAM-1 expression and eosinophil recruitment in Onchocerca volvulus keratitis.
- Sensitive and specific serodiagnosis of onchocerciasis with recombinant hybrid proteins.
- Eliminating onchocerciasis as a public health problem: the beginning of the end.
- Can ivermectin mass treatments eliminate onchocerciasis in Africa?
- Could antibiotics cure river blindness?
- An internal control for the detection of Onchocerca volvulus DNA by PCR-ELISA and rapid detection of specific PCR products by DNA Detection Test Strips.
- HIV infection and tropical parasitic diseases - deleterious interactions in both directions?
- Good news on a tropical disease.
- Ecdysteroids and oocyte development in the black fly Simulium vittatum.
- Differential cytokine and antibody responses to adult and larval stages of Onchocerca volvulus consistent with the development of concomitant immunity.
- Onchocerca volvulus-exposed persons fail to produce interferon-gamma in response to O. volvulus antigen but mount proliferative responses with interleukin-5 and IL-13 production that decrease with increasing microfilarial density.
- Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions.
- The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness.
- Survey of blindness and visual impairment in Bioko, Equatorial Guinea.
- Factors associated with coverage in community-directed treatment with ivermectin for onchocerciasis control in Oyo State, Nigeria.
- Antigenic mimicry: Onchocerca volvulus antigen-specific T cells and ocular inflammation.
- Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans.
- Macrofilaricides and onchocerciasis control, mathematical modelling of the prospects for elimination.
- Structural analysis and antibody response to the extracellular glutathione S-transferases from Onchocerca volvulus.
- [Parasitosis by Onchocerca volvulus].
- Black flies (Diptera: Simuliidae) of French Guiana: cytotaxonomy and a preliminary list of species.
- Community-based ivermectin therapy for onchocerciasis: comparison of three methods of dose assessment.
- Combined benefits of annual mass treatment with ivermectin and cattle zooprophylaxis on the severity of human onchocerciasis in northern Cameroon.
- The Carter Center's assistance to river blindness control programs: establishing treatment objectives and goals for monitoring ivermectin delivery systems on two continents.
- Eliminating onchocerciasis after 14 years of vector control: a proved strategy.
- Blindness in Africa: present situation and future needs.
- A dominant role for Fc gamma receptors in antibody-dependent corneal inflammation.
- Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis.
- Simulium cuasiexiguum, a new blackfly species (Diptera: Simuliidae) from the Minaçu area in the State of Goiás, Central Brazil.
- Distinct roles for PECAM-1, ICAM-1, and VCAM-1 in recruitment of neutrophils and eosinophils to the cornea in ocular onchocerciasis (river blindness).
- Paper chromatography hybridization: a rapid method for detection of Onchocerca volvulus DNA amplified by PCR.
- Early human infection with Onchocerca volvulus is associated with an enhanced parasite-specific cellular immune response.
- Hyperreactive onchocerciasis exhibits reduced arachidonate and linoleate levels in serum triglycerides.
- Community-directed treatment of onchocerciasis with ivermectin in Takum, Nigeria.
- Corneal blindness: a global perspective.
- CXC chemokine receptor 2 but not C-C chemokine receptor 1 expression is essential for neutrophil recruitment to the cornea in helminth-mediated keratitis (river blindness).
- Eosinophil granule proteins in serum and urine of patients with helminth infections and atopic dermatitis.
- Use of the recombinant Onchocerca volvulus protein Ov20/OvS1 for the immunodiagnostic differentiation between onchocerciasis and mansonelliasis and for the characterization of hyperreactive onchocerciasis (sowda).
- Onchocerciasis in a nonendemic population: clinical and immunologic assessment before treatment and at the time of presumed cure.
- Onchocerca ochengi transmission dynamics and the correlation of O. ochengi microfilaria density in cattle with the transmission potential.
- Development of a recombinant antigen vaccine against infection with the filarial worm Onchocerca volvulus.
- A rapid-format antibody card test for diagnosis of onchocerciasis.
- Impaired eosinophil recruitment to the cornea in P-selectin-deficient mice in Onchocerca volvulus keratitis (River blindness).
- CD4(+) depletion selectively inhibits eosinophil recruitment to the cornea and abrogates Onchocerca volvulus keratitis (River blindness).
- Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis.
- Looking forward to 20/20: a focus on the epidemiology of eye diseases.
- The epidemiology of human hookworm infections in the southern region of Mali.
- Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship.
- Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries.
- Fine specificity of autoantibodies to calreticulin: epitope mapping and characterization.
- Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift.
- A health club for a community school in south-eastern Nigeria: influence on adult perception of onchocerciasis and compliance with community-based ivermectin therapy.
- New species records for the blackfly (Diptera-simuliidae) fauna of Argentina with description of adults, pupa and larva of Simulium oyapockense s. l. And S. seriatum.
- Immunity to onchocerciasis: cells from putatively immune individuals produce enhanced levels of interleukin-5, gamma interferon, and granulocyte-macrophage colony-stimulating factor in response to Onchocerca volvulus larval and male worm antigens.
- Treatment with ivermectin: what works in one community may not work in another.
- The Simulium damnosum complex in western Uganda and its role as a vector of Onchocerca volvulus.
- [Semi-annular pre-equatorial scleral ectasia in a patient with glaucoma and onchocerciasis].
- Where health care has no access: the nomadic populations of sub-Saharan Africa.
- Interleukin-12 modulates T-cell responses to microfilariae but fails to abrogate interleukin-5-dependent immunity in a mouse model of onchocerciasis.
- Comparative analysis of glycosylated and nonglycosylated filarial homologues of the 20-kilodalton retinol binding protein from Onchocerca volvulus (Ov20).
- Human onchocerciasis and tetanus vaccination: impact on the postvaccination antitetanus antibody response.
- WHO celebrates triumph over river blindness.
- An essential role for antibody in neutrophil and eosinophil recruitment to the cornea: B cell-deficient (microMT) mice fail to develop Th2-dependent, helminth-mediated keratitis.
- Eotaxin expression in Onchocerca volvulus-induced dermatitis after topical application of diethylcarbamazine.
- [Effect of Onchocerca volvulus infestation on plasma vitamin A concentration in school children in a rural region of Cameroon].
- Onchocerciasis modulates the immune response to mycobacterial antigens.
- Regulatory effects of Th1-type (IFN-gamma, IL-12) and Th2-type cytokines (IL-10, IL-13) on parasite-specific cellular responsiveness in Onchocerca volvulus-infected humans and exposed endemic controls.
- Rapid assessment of onchocerciasis endemicity.
- Temporal recruitment of neutrophils and eosinophils to the skin in a murine model for onchocercal dermatitis.
- [Conjunctivitis and ocular parasitic diseases].
- Prenatal immune priming in onchocerciasis-onchocerca volvulus-specific cellular responsiveness and cytokine production in newborns from infected mothers.
- Analysis of renal function in onchocerciasis patients before and after therapy.
- Induction of histamine release in parasitized individuals by somatic and cuticular antigens from Onchocerca volvulus.
- Pathogenesis of onchocercal keratitis (River blindness).
- Population biology of human onchocerciasis.
- Distribution of the blinding and nonblinding strains of Onchocerca volvulus in Nigeria.
- Comparison of serological and parasitological assessments of Onchocerca volvulus transmission after 7 years of mass ivermectin treatment in Mexico.
- Independent evaluation of onchocerciasis rapid assessment methods in Benue State, Nigeria.
- Onchocerciasis and epilepsy: a matched case-control study in the Central African Republic.
- Onchocerciasis.
- Candidate parasitic diseases.
- Pool screen polymerase chain reaction for estimating the prevalence of Onchocerca volvulus infection in Simulium damnosum sensu lato: results of a field trial in an area subject to successful vector control.
- Eosinophil sequestration and activation are associated with the onset and severity of systemic adverse reactions following the treatment of onchocerciasis with ivermectin.
- Geographical determinants of onchocerciasis transmission in a forest/savannah transition zone : two villages of the mbam focus
- [Geographic determinants of onchocerciasis transmission in a forest-savannah transition zone: an example of 2 villages of the Mbam focus (central region, Cameroon)].
- Incorporating gender in the anthropology of infectious diseases.
- The effects of ivermectin on onchocercal skin disease and severe itching: results of a multicentre trial.
- Is apoptosis involved in mechanisms to eliminate Onchocerca ochengi during Simulium damnosum s.l. immune response?
- A cocktail of recombinant Onchocerca volvulus antigens for serologic diagnosis with the potential to predict the endemicity of onchocerciasis infection.
- Ivermectin influence on the mast cell activity in nodules of onchocerciasis patients.
- Treatment of onchocerciasis with ivermectin (Province of Bururi, Burundi): parasitologic and clinical evaluation of different periodicities of treatment.
- Onchocerciasis and Chagas' disease control: the evolution of control via applied research through changing development scenarios.
- Willingness to pay for community-based ivermectin distribution: a study of three onchocerciasis-endemic communities in Nigeria.
- Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10.
- Prevalence of Onchocerca volvulus nodules in the Sankuru River Valley, Democratic Republic of the Congo, and reliability of verbal assessment as a method for determining prevalence.
- Blue-yellow colour vision in an onchocercal area of northern Nigeria.
- [Ten Years of Mectizan in Africa: Partnerships for Long-Term Success. Conference proceedings. Mali, November 4-5, 1997].
- [Partnerships for prolonged success in onchocerciasis control in Guinea].
- Detection of the filarial parasite Mansonella streptocerca in skin biopsies by a nested polymerase chain reaction-based assay.
- Detection of Onchocerca volvulus infection by O-150 polymerase chain reaction analysis of skin scratches.
- [Progress in the control of world blindness and future perspectives].
- [Synthesis of the blindness situation in the countries of the Organization for Cooperation and Coordination in the Control of Major Endemic Diseases].
- Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis.
- Chemotherapy for onchocerciasis: results of in vitro experiments with promising new compounds.
- Novel, sensitive and low-cost diagnostic tests for 'river blindness'--detection of specific antigens in tears, urine and dermal fluid.
- The role of eosinophils and neutrophils in helminth-induced keratitis.
- IL-5-dependent immunity to microfilariae is independent of IL-4 in a mouse model of onchocerciasis.
- Current status of onchocerciasis in Colombia.
- [Indication of Mectizan in human medicine other than onchocerciasis].
- [Distribution and treatment using ivermectin under community directives].
- [The strategic role of information, education and communication in treatment programs using ivermectin (Mectizan) under community directives].
- [Mectizan and onchocerciasis: 10 years of Mectizan in Africa, a partnership for prolonged success].
- [Partnerships and distribution of Mectizan. Distribution of ivermectin in countries at war].
- [Partnerships and distribution of Mectizan. Sector investment programs for an integrated approach to investment loans].
- [Partnerships and the distribution of Mectizan. Ministries of health].
- [Parnerships and the distribution of Mectizan. The example of the onchocerciasis control program].
- [Improvement in the quality of life in rural Africa (AFRICARE) in the face of onchocerciasis in Chad (Mectizan donation program)].
- [Partnerships and the distribution of Mectizan. The role of a non-governmental development organization in a country with endemic onchocerciasis].
- [The placement of partnerships for Mectizan distribution systems].
- [The Mectizan donation program in Gabon: progress and perspectives of distribution in the focus of onchocerciasis (1991-1997)].
- [Onchocerciasis control program in Chad: the Mectizan donation].
- [Onchocerciasis in Tanzania].
- [Onchocerciasis in African countries not included in the onchocerciasis control program].
- [The African onchocerciasis control program: essential characteristics].
- [Onchocerciasis in West Africa. Strategies for mass treatment under community directives in Ghana].
- [Onchocerciasis in the Ivory Coast].
- [Onchocerciasis control in Senegal: evaluation of 10 years of control].
- [The beginning of the OPC and the status of onchocerciasis in western Africa before control measures].
- [The onchocerciasis control program in West Africa (OCP): essential characteristics].
- [Contribution of mectizan to the control of onchocerciasis. Effect on transmission after 8 years of treatment].
- [Contribution of mectizan to the control of onchocerciasis. Effect on transmission: evaluation of 9 years of treatment in West Africa].
- [Contribution of mectizan to the control of onchocerciasis. Impact on ocular lesions].
- [Onchocerciasis and the Mectizan donation program].
- Three probable cases of Loa loa encephalopathy following ivermectin treatment for onchocerciasis.
- Ivermectin distribution using community volunteers in Kabarole district, Uganda.
- [Large dams, health and nutrition in Africa: beyond the controversy].
- [Onchodermatitis (sowda) in patients in Yémen. Clinical and histologic course after treatment with ivermectin].
- The Ov20 protein of the parasitic nematode Onchocerca volvulus. A structurally novel class of small helix-rich retinol-binding proteins.
- Immunization with the cross-reactive antigens Ov39 from Onchocerca volvulus and hr44 from human retinal tissue induces ocular pathology and activates retinal microglia.
- Differences in cytokine responses to Onchocerca volvulus extract and recombinant Ov33 and OvL3-1 proteins in exposed subjects with various parasitologic and clinical states.
- Protective responses against skin-dwelling microfilariae of Onchocerca lienalis in severe combined immunodeficient mice.
- Blindness and visual impairment in a region endemic for onchocerciasis in the Central African Republic.
- Olecranon lesions caused by Onchocerca skrjabini in wild Japanese serows (Capricornis crispus).
- Production of both IFN-gamma and IL-5 by Onchocerca volvulus S1 antigen-specific CD4+ T cells from putatively immune individuals.
- The diverse expression of immunity in humans at distinct states of Onchocerca volvulus infection.
- Onchocerca volvulus: comparison of field collection methods for the preservation of parasite and vector samples for PCR analysis.
- Required duration of combined annual ivermectin treatment and vector control in the Onchocerciasis Control Programme in west Africa.
- Impact of annual dosing with ivermectin on progression of onchocercal visual field loss.
- Visual field constriction as a cause of blindness or visual impairment.
- The novel cuticular collagen Ovcol-1 of Onchocerca volvulus is preferentially recognized by immunoglobulin G3 from putatively immune individuals.
- RANTES in onchocerciasis: changes with ivermectin treatment.
- In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness.
- Low-molecular-weight protein ligands from Onchocerca volvulus preferentially stimulate the human gammadelta T cell Vdelta1+ subset.
- Maintaining compliance to ivermectin in communities in two West African countries.
- Absence of cellular responses to a putative autoantigen in onchocercal chorioretinopathy: cellular autoimmunity in onchocercal chorioretinopathy.
- Immunoregulation in onchocerciasis: predominance of Th1-type responsiveness to low molecular weight antigens of Onchocerca volvulus in exposed individuals without microfilaridermia and clinical disease.
- Immunoregulation in onchocerciasis: persons with ocular inflammatory disease produce a Th2-like response to Onchocerca volvulus antigen.
- Elevations in granulocyte-macrophage colony-stimulating factor and interleukin-5 levels precede posttreatment eosinophilia in onchocerciasis.
- Onchocerciasis in Ecuador: evolution of chorioretinopathy after amocarzine treatment.
- Polymerase chain reaction-based assessment after macrofilaricidal therapy in Onchocerca volvulus infection.
- Reactivity of various leishmanial antigens in a direct agglutination test and their value in differentiating post-kala azar dermal leishmaniasis from leprosy and other skin conditions.
- Absence of cellular responses to a putative autoantigen in onchocercal chorioretinopathy. Cellular autoimmunity in onchocercal chorioretinopathy.
- Ivermectin-induced immunopotentiation in onchocerciasis: recognition of selected antigens following a single dose of ivermectin.
- Molecular cloning, expression, and localization of E1, an Onchocerca volvulus antigen with similarity to brain ankyrin.
- Red-dot card test of the paracentral field as a screening test for optic nerve disease in onchocerciasis.
- The prevalence of epilepsy follows the distribution of onchocerciasis in a west Ugandan focus.
- Immunoglobulin G subclass responses of children during infection with Onchocerca volvulus.
- Eye disease in an onchocerciasis-endemic area of the forest-savanna mosaic region of Nigeria.
- Immunoglobulin kappa chain allotypes (KM) in onchocerciasis.
- Knowledge, attitudes and practices during a community-level ivermectin distribution campaign in Guatemala.
- Onchocerca volvulus larval antigen, OvB20, induces partial protection in a rodent model of onchocerciasis.
- Interleukin 4 and T helper type 2 cells are required for development of experimental onchocercal keratitis (river blindness).
- The treatment of scabies with ivermectin.
- Human autoantibody to defensin: disease association with hyperreactive onchocerciasis (sowda).
- Implementation of health initiatives during a cease-fire--Sudan, 1995.
- [Health indicators of a population in an agro-industrial complex of southern Cameroon].
- [The use of ivermectin in the control of onchocerciasis].
- Onchocerciasis in Ecuador: ocular findings in Onchocerca volvulus infected individuals.
- WHO's special programmes: undermining from above.
- Impact of combined large-scale ivermectin distribution and vector control on transmission of Onchocerca volvulus in the Niger basin, Guinea.
- Investigation of cross-reactions against Trichinella spiralis antigens by enzyme-linked immunosorbent assay and enzyme-linked immunoelectrotransfer blot assay in patients with various diseases.
- Global data on blindness.
- Socioeconomic consequences of blinding onchocerciasis in west Africa.
- Evaluation of Onchocerca volvulus-specific IgG4 subclass serology as an index of onchocerciasis transmission potential of three Gabonese villages.
- [Control of onchocerciasis vectors in West Africa: description of the logistics adapted for a large-scale public health program].
- The World Health Organisation in Africa.
- Blindness from uveitis in a hospital population in Sierra Leone.
- Epitopes of the Onchocerca volvulus RAL1 antigen, a member of the calreticulin family of proteins, recognized by sera from patients with onchocerciasis.
- HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection.
- Recent advances in tropical medicine.
- Ivermectin-facilitated immunity in onchocerciasis; activation of parasite-specific Th1-type responses with subclinical Onchocerca volvulus infection.
- Prevalence of blindness and low vision of people over 30 years in the Wenchi district, Ghana, in relation to eye care programmes.
- Influence of suramin on the expression of Fc receptors and other markers on human monocytes and U937 cells, and on their phagocytic properties.
- Major retinal cell components recognized by onchocerciasis sera are associated with the cell surface and nucleoli.
- The significance of blood levels of IgM, IgA, IgG and IgG subclasses in Sudanese visceral leishmaniasis patients.
- Molecular cloning of an Onchocerca volvulus extracellular Cu-Zn superoxide dismutase.
- Distribution and aetiology of blindness and visual impairment in mesoendemic onchocercal communities, Kaduna State, Nigeria. Kaduna Collaboration for Research on Onchocerciasis.
- Setting the stage for onchocerciasis.
- Neutrophil activation in ivermectin-treated onchocerciasis patients.
- Immunologic cross-reactivity in the pathogenesis of ocular onchocerciasis.
- Preliminary evaluation of recombinant Onchocerca volvulus antigens for serodiagnosis of onchocerciasis.
- An immunohistochemical analysis of onchocercal nodules: evidence for an interaction between macrophage MRP8/MRP14 and adult Onchocerca volvulus.
- Calreticulin synthetic peptide analogues: anti-peptide antibodies in autoimmune rheumatic diseases.
- Visual loss in an onchocerciasis endemic community in Sierra Leone.
- Ivermectin dose assessment without weighing scales.
- Prevalence of depigmentation of the shins: a simple and cheap way to screen for severe endemic onchocerciasis in Africa.
- [National entomological teams of the western extension zone of the Onchocerciasis Control Program (OCP) in west Africa from 1986 to 1990].
- Cytological and isoenzyme analysis of the Bucay and Quevedo cytotypes of the Onchocerciasis vector Simulium exiguum (Diptera: Simuliidae) in Ecuador.
- Diethylcarbamazine in the treatment of patients with onchocerciasis.
- Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment.
- Onchocerciasis in Ecuador: the situation in 1989.
- Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca volvulus.
- Onchocerciasis in members of an expedition to Cameroon: role of advice before travel and long term follow up.
- The profile of IgG and IgG subclasses of onchocerciasis patients.
- Suppression of human lymphocyte responses to specific and non-specific stimuli in human onchocerciasis.
- Molecular cloning and characterization of recombinant parasite antigens for immunodiagnosis of onchocerciasis.
- Interleukin-5 and the posttreatment eosinophilia in patients with onchocerciasis.
- Immunological crossreactivity between a cloned antigen of Onchocerca volvulus and a component of the retinal pigment epithelium.
- Subtle early features of onchocerciasis in a European.
- Immunoregulation in onchocerciasis. Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy.
- Causes of blindness and visual handicap in the Central African Republic.
- Experimental ocular onchocerciasis in cynomolgus monkeys. IV. Chorioretinitis elicited by Onchocerca volvulus microfilariae.
- Ocular manifestations of onchocerciasis in a rain forest area of west Africa.
- [Control of onchocerciasis with ivermectin: results of a mass campaign in northern Cameroon].
- The risk and dynamics of onchocerciasis recrudescence after cessation of vector control.
- Viability of adult Onchocerca volvulus after six 2-weekly doses of ivermectin.
- Onchocerciasis distribution and severity in five West African countries.
- Suramin affects DNA synthesis in HeLa cells by inhibition of DNA polymerases.
- The influence of food on the pharmacokinetics of CGP 6140 (amocarzine) after oral administration of a 1200 mg single dose to patients with onchocerciasis.
- Pharmacokinetics of CGP 6140 (amocarzine) after oral administration of single 100-1600 mg doses to patients with onchocerciasis.
- Cell-mediated immunity against human retinal extract, S-antigen, and interphotoreceptor retinoid binding protein in onchocercal chorioretinopathy.
- Humoral autoimmune response against S-antigen and IRBP in ocular onchocerciasis.
- Cytokine regulation of antigen-driven immunoglobulin production in filarial parasite infections in humans.
- The predicted and observed decline in onchocerciasis infection during 14 years of successful control of Simulium spp. in west Africa.
- Immunopathology of ocular onchocerciasis. I. Inflammatory cells infiltrating the anterior segment.
- Community-based treatment of onchocerciasis with ivermectin: acceptability and early adverse reactions.
- Adverse reactions after large-scale treatment of onchocerciasis with ivermectin: combined results from eight community trials.
- Unique recognition of a low molecular weight Onchocerca volvulus antigen by IgG3 antibodies in chronic hyper-reactive oncho-dermatitis (Sowda).
- Experimental ocular onchocerciasis in cynomolgus monkeys. II. Chorioretinitis elicited by intravitreal Onchocerca lienalis microfilariae.
- Biosystematics and distribution of simuliid vectors of human onchocerciasis in South America.
- Molecular cloning of an immunodominant antigen of Onchocerca volvulus.
- Effect of single-dose ivermectin therapy on human Onchocerca volvulus infection with onchocercal ocular involvement.
- Isolation and characterization of expression cDNA clones encoding antigens of Onchocerca volvulus infective larvae.
- Autoantibody induced by experimental Onchocerca infection. Effect of different routes of administration of microfilariae and of treatment with diethylcarbamazine citrate and ivermectin.
- Characterization of an immunodominant Onchocerca volvulus antigen with patient sera and a monoclonal antibody.
- Identification of vector species (Diptera:Simuliidae) of human onchocerciasis in the amazonia focus of Brazil and Venezuela.
- Antibodies to tubulin in patients with parasitic infections.
- Ocular findings in a double-blind study of ivermectin versus diethylcarbamazine versus placebo in the treatment of onchocerciasis.
- Drug treatment as an onchocerciasis control measure.
- Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.
- The effect of moderate urine alkalinisation on low dose diethylcarbamazine therapy in patients with onchocerciasis.
- Experimental ocular onchocerciasis in cynomolgus monkeys.
- [The Brazilian focus of onchocerciasis: new observations in the areas of the Mucajaà and Catrimâni rivers, Territory of Roraima].
- A force-of-infection model for onchocerciasis and its applications in the epidemiological evaluation of the Onchocerciasis Control Programme in the Volta River basin area.
- Human macrophages and T-lymphocyte subsets infiltrating nodules of Onchocerca volvulus.
- Onchocerciasis now.
- Common causes of blindness in Zaïre.
- Social responsibilities in ophthalmology.
- Eosinophilic cellulitis as a manifestation of onchocerciasis.
- IgE production in vitro by peripheral blood mononuclear cells of patients with parasitic helminth infections.
- Ophthalmology in developing countries.
- [Treatment of onchocerciasis with low, increasing doses of suramin in hyperendemic communities of Western Africa: 2. Clinical parasitologic and ophthalmologic results in a zone where transmission is controlled].
- Cost-effectiveness of blindness prevention by the Onchocerciasis Control Programme in Upper Volta.
- Recent developments in the treatment of onchocerciasis.
- My student elective. Along the White Nile.
- Non-specific suppression of antigen-induced lymphocyte blastogenesis in Onchocerca volvulus infection in man.
- Cutaneous onchocerciasis in the horse: five cases in southwestern british columbia.
- [Incidence of blindness and its epidemiological aspects in a rural region of western Africa].
- Detection of IgE antibodies in onchocerciasis. Possibility of using allergens from Dipetalonema viteae extracts that cross-react with allergenic determinants in crude extracts of Onchocerca volvulus.
- An endemic disease survey of Bong County, Liberia.
- Circulating antigen-antibody complexes in onchocerciasis.
- IgE antibodies are more species-specific than IgG antibodies in human onchocerciasis and lymphatic filariasis.
- Equine onchocerciasis: lesions in the nuchal ligament of midwestern U.S. horses.
- Further trials of mebendazole and metrifonate in the treatment of onchocerciasis.
- Clinical trials of amodiaquine in onchocerciasis.
- Histochemical enzyme variation in Onchocerca volvulus microfilariae from rain-forest and Sudan-savanna areas of the Onchocerciasis Control Programme in West Africa.
- The six diseases of WHO. Onchocerciasis.
- Ocular changes with oral and transepidermal diethylcarbamazine therapy of onchocerciasis.
- Simuliidae of Goiás state and the Federal District (BrasÃlia). 1. A description of Simulium (Chirostilbia) dekeyseri, new species.
- Mineralized onchocercal lesions resembling tuberculosis in cattle. Report of cases from meat inspection.
- The immunology of filariasis. Scientific Working Group on Filariasis.
- Living larva of Onchocerca volvulus.
- Changes in visual function and in the posterior segment of the eye during treatment of onchocerciasis with diethylcarbamazine citrate.
- Circulating immune complexes in onchocerciasis.
- Analysis of the anticomplementary activity in sera of three African patients with parasitic and bacteriological infections.
- [Latency period in onchocerciasis].
- [Treatment of onchocerciasis in hyperendemic communities in West Africa with small, gradually increasing doses of suramin. 1. Parasitological results and ophthalmological surveillance in a region where transmission has not been interrupted].
- A three-year follow-up of ocular onchocerciasis in an area of vector control.
- Bovine and equine onchocerciasis in eastern North America with a discussion on cuticular morphology of Onchocerca spp. in cattle.
- Treatment of onchocerciasis.
- Lepromatous leprosy and onchocerciasis.
- Tanzania Filariasis Project: a provocative day test with diethylcarbamazine for the detection of microfilariae of nocturnally periodic Wuchereria bancrofti in the blood.
- Inflammatory reactions in onchocerciasis: a report on current knowledge and recommendations for further study.
- Epidemiological aspects of intraocular pressure in an onchocerciasis endemic area.
- [Epidemiologic status of onchocerciasis].
- The risk of optic atrophy following suramin treatment of ocular onchocerciasis.
- Bovine onchocerciasis caused by Onchocerca armillata and O. gutturosa.
- Visual field defects in onchocerciasis.
- Aspects of corneal changes in onchocerciasis.
- Further studies on the treatment of ocular onchocerciasis with diethylcarbamazine and suramin.
- Further observations on the relationship between ocular onchocerciasis and the head nodule, and on the possible benefit of nodulectomy.
- Evaluation of microfilaricidal effects in the cornea from topically applied drugs in ocular onchocerciasis: Trials with levamisole and mebendazole.
- Effects of various concentrations of diethylcarbamazine citrate applied as eye drops in ocular onchocerciasis, and the possibilities of improved therapy from continuous non-pulsed delivery.
- Onchocerciasis--out of oubliette.
- [Evolution of 9 years of ocular onchocerciasis in a village community of Western Africa].
- [Complex of species of Simuliidae].
- Ocular onchocerciasis.
- Species complexes in the Simuliidae.
- A simplified technique for counting onchocercal microfilariae in skin snips.
- The problem of uveitis in Bendel State of Nigeria: experience in Benin City.
- [Onchocerca cervicalis infection in Quebec: clinical signs and diagnostic methods].
- Dangerous reactions to treatment of onchocerciasis with diethylcarbamazine.
- The microfilarial load in the anterior segment of the eye. A parameter of intensity of onchocerciasis.
- Preliminary studies on the histochemical differentiation of strains of Onchocerca volvulus microfilariae in Togo.
- Droplet degeneration of the cornea in North Cameroon. Prevalence and clinical appearances.
- Antigenic diversity among Onchocerca volvulus in Nigeria, and immunological differences between onchocerciasis in the savanna and forest of Cameroon.
- Morphology of posterior segment lesions of the eye in patients with onchocerciasis.
- Transmission in utero of microfilariae of Onchocerca volvulus.
- [Attempt at a collective treatment with diethylcarbamazine in a village in the region of Bamako (Mali) where onchocerciasis is hyperendemic].
- Intra-ocular pressure in onchocerciasis. Some preliminary results of a field evaluation.
- Epidemiological studies on onchocerciasis by means of a new field technique.
- A new technique for the determination of microfilarial densities in onchocerciasis.
- Editorial: Onchocerciasis.
- Onchocerciasis in Canada.
- Letter: Onchocerciasis in Canada.
- Editorial: Onchocerciasis--river blindness.
- Onchocerciasis in Canada.
- An evaluation of skin snip techniques used in the quantitative assessment of microfilarial densities of Onchocerca volvulus.
- [(A method of evaluating microfilaria densities of Onchocerca volvulus Leuckart, 1893, in onchoceriasis patients. Assessment of microfilarial densities by site and levels of prevelance in skin biopsies; variations of microfilarial densities over a 24 hour period)].
- A simple technique for maintaining Stimulium adults, including onchocerciasis vectors, under artificial conditions.
- [Results of 2 eye examinations carried out with an interval of 6 years in 2 Upper Volta villages where onchocerciasis is endemic].
- Letter: Living microfilariae of Onchocerca volvulus in the cornea.
- A comparison of African and European serum levels of immunoglobulin E.
- Kerato-uveal changes in leprosy and onchocerciasis: a question of immunity.
- Ocular onchocerciasis in Malawi. A comparative study of 500 patients and 500 controls.
- Mating, blood feeding, and oviposition of Simulium damnosum Theobald in the laboratory.
- Impacted microfilaria in the lens capsule.
- United States Naval Medical Research Units in Africa.
- [A method of evaluating the density of the microfilaria of Onchocerca volvulus Leuckart, 1893 in patients with onchocerciasis: technic and reading time of skin biopsies].
- Microfilaruria in onchocerciasis. A clinical and epidemiological follow-up study in the Republic of Chad.
- Heterophile antibodies in Nigerian sera.
- Ovicides in Stimulium control.
- The effects of drugs on Onchocerca volvulus. 4. Trials of melarsonyl potassium.
- Tumoral calcinosis--an unrecognized disease.
- Prospects for the control of onchocerciasis in Africa with special reference to the Volta River basin.
- The impact of insecticide-resistance on control of vectors and vector-borne diseases.
- Artificial feeding of East African female Simuliidae (Diptera), including vectors of human onchocerciasis.
- Onchocerciasis.
- Artificial feeding of Simulium vectors of human and bovine onchoceriasis.
- Reinfections with Onchocerca volvulus in cured patients exposed to continuing transmission.
- The simulium control scheme at Abuja, Northern Nigeria, and its effect on the prevalence of onchocerciasis in the area.
- Experiments on the chemoprophylaxis of Onchocerca volvulus infection.
- The intake and transmissibility of Onchocerca volvulus microfilariae by Simulium damnosum fed on patients treated with Diethylcarbamazine, suramin or Mel W.
- The effects of drugs on Onchocerca volvulus. 3. Trials of suramin at different dosages and a comparison of the brands Antrypol, Moranyl and Naganol.
- The effects of drugs on Onchocerca volvulus. 2. The antimonial preparations TWSb and MSbE.
- The effects of drugs on Onchocerca volvulus. 1. Methods of assessment, population dynamics of the parasite and the effects of diethylcarbamazine.
- Onchocerciasis.
- Onchocerciasis in Kenya 9, 11 and 18 years after elimination of the vector.
- A method of rearing Simulium damnosum Theobald (Diptera; Simuliidae) under artificial conditions.
- A review of the control of Simulium vectors of onchocerciasis.
- Surgical pathology in the course of the Nile.
- A simple laboratory method for testing the susceptibility of larvae of the Simulium neavei complex to insecticides.
- [OPHTHALMOLOGICAL ASPECTS OF ONCHOCERCIASIS IN GUATEMALA AND WEST AFRICA].
- Onchocerciasis.
- Onchocerciasis.
- ONCHOCERCIASIS IN BRITAIN.
- [BIOLOGY AND ECOLOGY OF THE FEMALE OF SIMULIUM DAMNOSUM THEOBALD, 1903, AS A FUNCTION OF THE BIOCLIMATIC ZONES OF WEST AFRICA. INFLUENCE ON THE EPIDEMIOLOGY OF ONCHOCERCIASIS].
- PESTICIDES: A CONTRIBUTION TO PUBLIC HEALTH.
- A standard method of assessing microfilarial densities on onchocerciasis surveys.
- The control of Simulium damnosum at Abuja, Northern Nigeria, 1955-60.
- Simuliidae and their relation to human onchocerciasis in northern Venezuela.
- Onchocerciasis and filariasis: Introduction.
- OCULAR LESIONS OF ONCHOCERCIASIS.
- The identification of the larvae of African Simulium.
- A survey of Simulium control in Africa.
- A review of recent advances in scientific knowledge of the symptomatology, pathology and pathogenesis of onchoceral infections.
- Entomological aspects of African onchocerciasis and observations on Simulium in the Sudan.
- Onchocerciasis in the Sudan.
- The identification of infective filarial larvae in Simuliidae.
- Onchocerciasis presenting without dermatitis.
- OCULAR ONCHOCERCIASIS IN NORTHERN GHANA: A TREATMENT SURVEY.
- Aspects of black-fly control and entomology in the New World in relation to the Simulium problem in Nigeria.
- Eye diseases in African children; with special reference to onchocerciasis and malnutrition.
- The eradication of Simulium neavei from Kenya.
- Posterior degenerative lesion of onchocerciasis.
- Acute ocular onchocerciasis and its treatment.
- Natural history of onchocerciasis.
- Onchocerciasis and filariasis: Introduction.
- Evaluation of new onchocercidal drugs used in Guatemala.
- Resistance of Onchocerca volvulus microfilariae to diethylcarbamazine.
- Notes and observations on onchocerciasis in Guatemala.
- [Sandflies & onchocerciasis in Somaliland].
- Simuliidae and their relation to onchocerciasis in the Sudan.
- The pathogenicity of Onchocerca volvulus in relation to lymphadenopathy and elephantiasis.
- Observations on the chemotherapy of onchocerciasis in Bahr el Ghazal Province, Sudan.
- Simuliid vectors of onchocerciasis in Guatemala.
- Bionomics of the vectors of onchocerciasis in the Ethiopian geographical region.
- New observations on ocular onchocerciasis; related pathological methods and the pathogenesis of the various eye lesions.
- Factors in the pathogenesis of ocular onchocerciasis.
- ONCHOCERCIASIS.
- Incidence of human infection with onchocerciasis in different communities in relation to the incidence and type of the ocular lesions.
- Onchocerciasis.
- A histological study of onchocerciasis treated with hetrazan.
- Ocular onchocerciasis.
- Onchocerca volvulus in Angola, Africa.
- A case of onchocerciasis in London and its treatment with hetrazan.
- Ocular Onchocerciasis in Guatemala. An Investigation of 1,215 Natives Infected With Onchocerca Volvulus.
- OCULAR ONCHOCERCIASIS Including an Investigation in the Gold Coast.
- Ocular Syndrome in Onchocerciasis.
- Onchocerciasis.
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