Food/Drug Interactions

Food/Drug Interactions
Presentation by:M. Burns, PhD, RD

Drug therapy
* Long-term care
* Numerous drugs
* Therapeutic side effects
* Alters nutritional status

JCAHO
* Joint
* Commission
* Accreditation
* Healthcare
* Organizations

Drug-induced malnutrition
* Numerous meds at one time
* Sudden increased need
* Genetics
* Body composition

High-risk Groups
* Developing fetus, infants
* Pregnant women
* Elderly
* Chronically ill

What is a drug?
* Chemical that interacts with a living organism to produce physiologic response
What is bioavailability?
* Proportion of drug that passes into the circulation
* Reflects both ABSORPTION and METABOLIC USE

Remember...

with increased meds there is an increased chance for drug-nutrient interactions.

Commonly affected nuts
* Calcium
* Folate
* Pyridoxine
* Vitamin A
Effects on Nut’l Status
* Dietary intake
* Affects nutrient absorption
* Affects nutrient metabolism
* Include meds in SOAP note
* Assess nut’l status in regards to interactions

Appetite -- Table 18.1 and 18.3
Dysgeusia -- change taste sensation
Hypogeusia -- reduce acuity of taste
Aftertaste -- Table 18.2
Cravings -- duiretics crave salty foods
Absorbed in small intestine, therefore, FNI are common here…
Transit time -- laxatives, diuretics
Bile acid -- affects fat absorption, chol, ADEK
GI environment -- antacids changes pH
Mucosal lining -- laxatives
Antivitamins -- used in chemo tx, rheumatoid arthritis
MAO inhibitors -- monoamine oxidase, calls for tyramine-restricted diets
Anticonvulsants -- phenobarbital -- low folate, biotin and VD
Oral conceptives -- folate and B6
Anti-inflammatory -- Ca absorption reduced and excretion increased can cause GI bleeding leading to Iron deficiency and protein loss
Anti-hypertensives -- Diuretics affect mineral metabolism (K, Ca, Mg, Zn)

Food / Drug Interactions.ppt