Immuno-epidemiology of Malaria

Immuno-epidemiology of malaria
Presentation by Klaus Dietz
Department of Medical Biometry
University of Tübingen, Germany
at
DIMACS Worksop 2006

Outline

* What is Immuno-epidemiology?
* What is malaria?
* Why model malaria immunity?
* Malaria immunity models: a brief history
* A within-host malaria model
* Concluding remarks

Serological surveys as immuno-epidemiological tools
A theoretical framework for immuno-epidemiology
A cartoon of immuno-epidemiological models
Malaria cycle
The challenge of malaria
Why model malaria immunity?
Original Eradication Plans
Points of attack of potential malaria vaccines
Malaria immunity models
Implications of unrealistic assumptions about the strength of immunity
Innate and adaptive immunity
Vaccine efficacy

Immuno-epidemiology of malaria.ppt