28 June 2009

Hyponatremia



Hyponatremia
By:James Yost, MD, MS, MBA
Emory Family Medicine

Hyponatremia
* Definition
* Epidemiology
* Physiology
* Pathophysiology
* Types
* Clinical Manifestations
* Diagnosis
* Treatment

* Definition:
o Commonly defined as a serum sodium concentration 135 meq/L
o Hyponatremia represents a relative excess of water in relation to sodium.
* Epidemiology:
* Physiology
o Serum sodium concentration regulation:
+ stimulation of thirst
+ secretion of ADH
+ feedback mechanisms of the renin-angiotensin-aldosterone system
+ renal handling of filtered sodium
+ Aldosterone

* Pathophysiology
Hypovolemic hyponatremia
* Nonrenal loss
* Renal Loss
Euvolemic hyponatremia
Redistributive hyponatremia
* Pseudohyponatremia
* Clinical Manifestations
* Diagnosis
* Laboratory tests
* Treatment
* Symptomatic or Acute
* IV Fluids
* Example:
* Asymptomatic or Chronic

Hyponatremia.ppt

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