http://mcb.berkeley.edu
Influence of Retinoids on Embryonic Chick Intestinal Development
J. Orion Rogers and Sheila Shomo
http://www.radford.edu
Vitamin A
https://camcom.ngu.edu
Acne: Evaluation and Management
Betsy Pfeffer MD
http://www.columbia.edu
Vitamins and minerals
http://www.csuchico.edu
Recurrent Respiratory Papillomatosis
Michael E. Decherd, MD, Ronald W. Deskin, MD
http://www2.utmb.edu
The Synthetic Retinoid
Arsen Khachatryan
http://ww2.biol.sc.edu
Fat-Soluble Vitamins
http://35-206-202.wiki.uml.
Acne Treatment and Therapeutic Strategies
Dr. Marie Andrades
http://www.pitt.edu
Psoriasis
Mark Gill, PharmD, Professor of Clinical Pharmacy
http://www-hsc.usc.edu
Nuclear Receptors and Cancer
Joe Lipsick
http://www.stanford.edu
462 Published articles on Retinoids
- Retinoids in the treatment of glioma: a new perspective.
- Retinoids as Promising Treatment for Non-alcoholic Fatty Liver Disease.
- Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells.
- Retinoids Reduce Formation of Keratin Aggregates in Heat-stressed Immortalized Keratinocytes from an Epidermolytic Ichthyosis Patient with a KRT10 Mutation*
- EMBO Retinoids 2011: Mechanisms, biology and pathology of signaling by retinoic acid and retinoic acid receptors.
- A study on the management of hidradenitis suppurativa with retinoids and surgical excision.
- Epidermolytic hyperkeratosis: a follow-up of 23 years of use of systemic retinoids.
- Regulation of keratin expression by retinoids.
- The thyroid hormone receptors modulate the skin response to retinoids.
- RIG-I is required for the inhibition of measles virus by retinoids.
- Design and Synthesis of 3,5-Disubstituted 1,2,4-Oxadiazole Containing Retinoids from a Retinoic Acid Receptor Agonist.
- Retinoids suppress cysteine-rich protein 61 (CCN1), a negative regulator of collagen homeostasis, in skin equivalent cultures and aged human skin in vivo.
- Bile retinoids imprint intestinal CD103+ dendritic cells with the ability to generate gut-tropic T cells.
- Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription.
- Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.
- p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process.
- Endogenous retinoids in mammalian growth plate cartilage: analysis and roles in matrix homeostasis and turnover.
- Retinoids regulate stem cell differentiation.
- Systemic retinoids: chemoprevention of skin cancer in transplant recipients.
- Anti-tumor effects of retinoids combined with trastuzumab or tamoxifen in breast cancer cells: induction of apoptosis by retinoid/trastuzumab combinations.
- Effective and sustained delivery of hydrophobic retinoids to photoreceptors.
- Retinoids for treatment of retinal diseases.
- Design and Synthesis of Potential New Apoptosis Agents: Hybrid Compounds Containing Perillyl Alcohol and New Constrained Retinoids.
- Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids.
- Retinoids regulate a developmental checkpoint for tissue regeneration in Drosophila.
- The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.
- Relationships among visual cycle retinoids, rhodopsin phosphorylation, and phototransduction in mouse eyes during light and dark adaptation.
- Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors.
- Plasma levels of retinoids, carotenoids and tocopherols in patients with mild obstructive sleep apnoea.
- Esterase 22 and beta-glucuronidase hydrolyze retinoids in mouse liver.
- Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung.
- Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.
- Retinoids and proliferative verrucous leukoplakia (PVL). A preliminary study.
- A possible contribution of retinoids to regulation of fetal B lymphopoiesis.
- Retinoids inhibit differentiation of hematopoietic osteoclast progenitors.
- A minute dose of 14C-{beta}-carotene is absorbed and converted to retinoids in humans.
- Retinoids inhibit measles virus through a type I IFN-dependent bystander effect.
- Retinoids induce differentiation and downregulate telomerase activity and N-Myc to increase sensitivity to flavonoids for apoptosis in human malignant neuroblastoma SH-SY5Y cells.
- The role of interphotoreceptor retinoid-binding protein on the translocation of visual retinoids and function of cone photoreceptors.
- Retinoids synergize with insulin to induce hepatic Gck expression.
- Detection of endogenous retinoids in the molluscan CNS and characterization of the trophic and tropic actions of 9-cis retinoic acid on isolated neurons.
- Effect of retinoids on UDP-glucuronosyltransferase 2B7 mRNA expression in Caco-2 cells.
- Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.
- Expanding the use of retinoids in acute myeloid leukemia: spotlight on bexarotene.
- Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation.
- Retinoids modulate expression of the endocytic partners megalin, cubilin, and disabled-2 and uptake of vitamin D-binding protein in human mammary cells.
- Synergistic Effects of PPARgamma Ligands and Retinoids in Cancer Treatment.
- Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo.
- Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes.
- Upregulation of P2Y2 receptors by retinoids in normal human epidermal keratinocytes.
- Congenital diaphragmatic hernia and retinoids: searching for an etiology.
- Retinoids induce cytochrome P450 3A4 through RXR/VDR-mediated pathway.
- Regulation of FoxP3 regulatory T cells and Th17 cells by retinoids.
- Retinoids, rexinoids and their cognate nuclear receptors: character and their role in chemoprevention of selected malignant diseases.
- Retinoids regulate genes involved in retinoic acid synthesis and transport in human myometrial and fibroid smooth muscle cells.
- Role of the translational repressor 4E-BP1 in the regulation of p21(Waf1/Cip1) expression by retinoids.
- Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts.
- Retinoids accelerate B lineage lymphoid differentiation.
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety.
- Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.
- Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids.
- Roles of retinoids and retinoic Acid receptors in the regulation of hematopoietic stem cell self-renewal and differentiation.
- The chemopreventive effect of retinoids on cellular NF-kappaB activity induced by NMU and NEU in human malignant keratinocytes.
- Increase of intracellular methylglyoxal levels as a mode of action of retinoids against psoriasis.
- Retinoids restore normal cyclic nucleotide sensitivity of mutant ion channels associated with cone dystrophy.
- A search for multidrug resistance modulators: the effects of retinoids in human colon carcinoma cells.
- Retinoids induce MMP-9 expression through RARalpha during mammary gland remodeling.
- Retinoids, vitamin D, invasion, and metastasis.
- MEK blockade converts AML differentiating response to retinoids into extensive apoptosis.
- Cyclic adenosine monophosphate-dependent cell type-specific modulation of mitogenic signaling by retinoids in normal and neoplastic lung cells.
- Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
- Retinoids induce growth inhibition and apoptosis in mast cell tumor cell lines.
- Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.
- Apoptosis induction by retinoids in eosinophilic leukemia cells: implication of retinoic acid receptor-alpha signaling in all-trans-retinoic acid hypersensitivity.
- A comparison of carotenoids, retinoids, and tocopherols in the serum and buccal mucosa of chronic cigarette smokers versus nonsmokers.
- Bmp2 and Gata4 function additively to rescue heart tube development in the absence of retinoids.
- Isolation of ribonuclease P activity from human epidermis and its regulation by retinoids in vitro.
- Retinoids activate the RXR/SXR-mediated pathway and induce the endogenous CYP3A4 activity in Huh7 human hepatoma cells.
- Retinoids during the in vitro transition from bovine morula to blastocyst.
- Clinical trials with retinoids for breast cancer chemoprevention.
- Retinoids and spermatogenesis: lessons from mutant mice lacking the plasma retinol binding protein.
- Retinoids have differing efficacies on alveolar regeneration in a dexamethasone-treated mouse.
- Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cells.
- Involvement of serum retinoids and Leiden mutation in patients with esophageal, gastric, liver, pancreatic, and colorectal cancers in Hungary.
- Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers.
- Receptor-related mechanism of proliferation inhibilion and apoptosis induetion of human tongue squamous cell line Tca8113 by retinoids.
- Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1.
- High concentrations of retinoids induce differentiation and late apoptosis in pancreatic cancer cells in vitro.
- Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.
- Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.
- Natural retinoids inhibit proliferation and induce apoptosis in pancreatic cancer cells previously reported to be retinoid resistant.
- Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids.
- A conserved retinoid X receptor (RXR) from the mollusk Biomphalaria glabrata transactivates transcription in the presence of retinoids.
- Concentrations of retinoids in early pregnancy and in newborns and their mothers.
- Activation of p53, inhibition of telomerase activity and induction of estrogen receptor beta are associated with the anti-growth effects of combination of ovarian hormones and retinoids in immortalized human mammary epithelial cells.
- The potential immunomodulatory effects of topical retinoids.
- Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells.
- The effect of doxorubicin and retinoids on proliferation, necrosis and apoptosis in MCF-7 breast cancer cells.
- Retinoids and pulmonary hypertension.
- Upregulation of CD44 and hyaluronate synthases by topical retinoids in mouse skin.
- Retinoids: inducers of tumor/growth suppressors.
- Retinoids arrest breast cancer cell proliferation: retinoic acid selectively reduces the duration of receptor tyrosine kinase signaling.
- Can transforming growth factor-beta1 and retinoids modify the activity of estradiol and antiestrogens in MCF-7 breast cancer cells?.
- Retinoic acid increases the expression of p53 and proapoptotic caspases and sensitizes keratinocytes to apoptosis: a possible explanation for tumor preventive action of retinoids.
- Retinoids and myelomonocytic growth factors cooperatively activate RARA and induce human myeloid leukemia cell differentiation via MAP kinase pathways.
- Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells. Cross-talk between the cAMP and the retinoic acid signaling pathways.
- Retinoids and cancer: antitumor effect of ATRA and of a new derivative of retinoic acid, IIF, on colon carcinoma cell lines CaCo-2 and HT-29.
- Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1.
- Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats.
- The specificity of alcohol dehydrogenase with cis-retinoids. Activity with 11-cis-retinol and localization in retina.
- The proteosome inhibitor MG132 attenuates retinoic acid receptor trans-activation and enhances trans-repression of nuclear factor kappaB. Potential relevance to chemo-preventive interventions with retinoids.
- Insulin-like growth factor binding protein-3 antagonizes the effects of retinoids in myeloid leukemia cells.
- Retinoids assist the cellular folding of the autosomal dominant retinitis pigmentosa opsin mutant P23H.
- Alpha-tocopherol and ascorbic acid decrease the production of beta-apo-carotenals and increase the formation of retinoids from beta-carotene in the lung tissues of cigarette smoke-exposed ferrets in vitro.
- Retinoic acid and retinoid X receptors are differentially expressed in thyroid cancer and thyroid carcinoma cell lines and predict response to treatment with retinoids.
- Analysis of retinoids and carotenoids: problems resolved and unsolved.
- Oxidative conversion of carotenoids to retinoids and other products.
- Retinoids and drugs of abuse: implications for neurological disease risk in human immunodeficiency virus type 1 infection.
- Retinoids act as multistep modulators of the major histocompatibility class I presentation pathway and sensitize neuroblastomas to cytotoxic lymphocytes.
- Transcription suppression of thromboxane receptor gene expression by retinoids in vascular smooth muscle cells.
- The transcription factor NGFI-B (Nur77) and retinoids play a critical role in acute neuroleptic-induced extrapyramidal effect and striatal neuropeptide gene expression.
- Functional specificity of two hormone response elements present on the human apoA-II promoter that bind retinoid X receptor alpha/thyroid receptor beta heterodimers for retinoids and thyroids: synergistic interactions between thyroid receptor beta and upstream stimulatory factor 2a.
- Retinoids regulate survival and antigen presentation by immature dendritic cells.
- Retinoids as a potential treatment for experimental puromycin-induced nephrosis.
- The role of vitamin D and retinoids in controlling prostate cancer progression.
- An International Evaluation of the Cancer-Preventive Potential of Nine Retinoids.
- A novel role for retinoids in patterning the avian forebrain during presomite stages.
- Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats.
- Acute radiolabeling of retinoids in eye tissues of normal and rpe65-deficient mice.
- Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids.
- Regulation of the cardiac mitochondrial membrane potential by retinoids.
- Retinoids, alveolus formation, and alveolar deficiency: clinical implications.
- Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.
- Retinoids and alcohol-related carcinogenesis.
- Vitamin A (retinoids) regulation of mouse melanoma growth and differentiation.
- Pharmacological doses of some synthetic retinoids can modulate both the aryl hydrocarbon receptor and retinoid receptor pathways.
- Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain.
- Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner.
- Absence of retinoids can induce motoneuron disease in the adult rat and a retinoid defect is present in motoneuron disease patients.
- Retinoids induce lumen morphogenesis in mammary epithelial cells.
- Bis-indols: a novel class of molecules enhancing the cytodifferentiating properties of retinoids in myeloid leukemia cells.
- Nuclear (receptor) power: retinoids in rat mesangioproliferative disease.
- The role of retinoids and retinoic acid receptors in normal hematopoiesis.
- Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line.
- The effect of retinoids on premalignant oral lesions: focus on topical therapy.
- Deficits in the posterior pharyngeal endoderm in the absence of retinoids.
- Retinoic acid receptors and retinoids are up-regulated in the developing and adult rat prostate by neonatal estrogen exposure.
- Retinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/Bax.
- Transcriptional induction of mitogen-activated protein kinase phosphatase 1 by retinoids. Selective roles of nuclear receptors and contribution to the antiapoptotic effect.
- Retinoids and lung cancer: targeting the right population.
- All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: a novel role for photoreceptor retinoids in the response to bright light?
- Selective alteration of gene expression in response to natural and synthetic retinoids.
- Human choriocarcinoma cell line JEG-3 produces and secretes active retinoids from retinol.
- Retinoids and carnosol suppress cyclooxygenase-2 transcription by CREB-binding protein/p300-dependent and -independent mechanisms.
- Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids.
- Classical and novel retinoids: their targets in cancer therapy.
- Retinoids, cisplatin and interferon-alpha in recurrent or metastatic cervical squamous cell carcinoma: clinical results of 2 phase II trials.
- Effect of natural and synthetic retinoids on the proliferation and differentiation of three canine melanoma cell lines.
- Increased antibody production by retinoids is related to the fusion partner of human hybridomas.
- Midkine is involved in kidney development and in its regulation by retinoids.
- Unique property of some synthetic retinoids: activation of the aryl hydrocarbon receptor pathway.
- Lung cancer prevention: retinoids and the epidermal growth factor receptor-a phoenix rising?
- Retinoids suppress epidermal growth factor-associated cell proliferation by inhibiting epidermal growth factor receptor-dependent ERK1/2 activation.
- Alveolar proliferation, retinoid synthesizing enzymes, and endogenous retinoids in the postnatal mouse lung. Different roles for Aldh-1 and Raldh-2.
- Effects of retinoids on the TGF-beta system and extracellular matrix in experimental glomerulonephritis.
- Isomerization of 11-cis-retinoids to all-trans-retinoids in vitro and in vivo.
- Where to next with retinoids for cancer therapy?
- Evidence for indirect control of phospholipase C (PLC-beta) by retinoids in Drosophila phototransduction.
- Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells.
- Possible role of retinoids in hepatitis B virus-associated liver damage.
- Metabolism and growth inhibition of four retinoids in head and neck squamous normal and malignant cells.
- Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids.
- Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
- Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators.
- Retinoids: new insight into smooth muscle cell growth inhibition.
- In vitro inhibition of proliferation of estrogen-dependent and estrogen-independent human breast cancer cells treated with carotenoids or retinoids.
- Characterization of a novel airway epithelial cell-specific short chain alcohol dehydrogenase/reductase gene whose expression is up-regulated by retinoids and is involved in the metabolism of retinol.
- Effects of receptor-selective retinoids on CYP26 gene expression and metabolism of all-trans-retinoic acid in intestinal cells.
- Effects of retinoids on cancerous phenotype and apoptosis in organotypic cultures of ovarian carcinoma.
- Retinoids for ovarian cancer prevention: laboratory data set the stage for thoughtful clinical trials.
- Up-regulation of steroid sulphatase activity in HL60 promyelocytic cells by retinoids and 1alpha,25-dihydroxyvitamin D3.
- Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells.
- A vertebrate aldo-keto reductase active with retinoids and ethanol.
- Potential role of retinoids in the therapy of renal disease.
- Retinoids induce fibroblast growth factor-2 production in endothelial cells via retinoic acid receptor alpha activation and stimulate angiogenesis in vitro and in vivo.
- Regulation of mouse kappa opioid receptor gene expression by retinoids.
- Effect of retinoids on growth inhibition of two canine melanoma cell lines.
- Modulation of the synaptic Ca2+ current in salamander photoreceptors by polyunsaturated fatty acids and retinoids.
- Retinoids as ligands and coactivators of protein kinase C alpha.
- The retinoids and cancer prevention mechanisms.
- Is there a role for retinoids to treat minimal residual disease in neuroblastoma?
- Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin A in liver of mice and rats.
- Retinoids: versatile biological response modifiers of vascular smooth muscle phenotype.
- Retinoic acid regulation of Cdx1: an indirect mechanism for retinoids and vertebral specification.
- Retinoids and arterial smooth muscle cells.
- beta-carotene is converted primarily to retinoids in rats in vivo.
- Transcriptional activation of the human ucp1 gene in a rodent cell line. Synergism of retinoids, isoproterenol, and thiazolidinedione is mediated by a multipartite response element.
- TCDD suppression of tissue transglutaminase stimulation by retinoids in malignant human keratinocytes.
- Retinoids stimulate leptin synthesis and secretion in human syncytiotrophoblast.
- Retinoids in embryonal development.
- Retinoids in chemoprevention and differentiation therapy.
- Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha.
- Retinoids and demethylating agents- looking for partners.
- Identification of receptor-selective retinoids that are potent inhibitors of the growth of human head and neck squamous cell carcinoma cells.
- Multiple effects of retinoids on the development of Sertoli, germ, and Leydig cells of fetal and neonatal rat testis in culture.
- The effect of lipid environment and retinoids on the ATPase activity of ABCR, the photoreceptor ABC transporter responsible for Stargardt macular dystrophy.
- Evidence that retinoic acid receptor beta induction by retinoids is important for tumor cell growth inhibition.
- The development of biologic end points in patients treated with differentiation agents: an experience of retinoids in prostate cancer.
- Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids.
- Advances in the development of retinoids as chemopreventive agents.
- SN-1, a novel leukemic cell line with t(11;16)(q23;p13): myeloid characteristics and resistance to retinoids and vitamin D3.
- A ligand of peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions.
- Morphogenetic action of retinoids and estrogens.
- Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids.
- Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids.
- Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.
- Mannose 6-phosphate/insulin-like growth factor II receptor mediates the growth-inhibitory effects of retinoids.
- Inhibition of proliferation and induction of apoptosis in soft tissue sarcoma cells by interferon-alpha and retinoids.
- Overexpression of retinoic acid receptor beta in head and neck squamous cell carcinoma cells increases their sensitivity to retinoid-induced suppression of squamous differentiation by retinoids.
- F-actin as a functional target for retro-retinoids: a potential role in anhydroretinol-triggered cell death.
- Retinoids: present role and future potential.
- Morphological clues from multilegged frogs: are retinoids to blame?
- Action of retinoids on embryonic and early postnatal testis development.
- Retinoids inhibit interleukin-12 production in macrophages through physical associations of retinoid X receptor and NFkappaB.
- Effect of retinoids on AOM-induced colon cancer in rats: modulation of cell proliferation, apoptosis and aberrant crypt foci.
- Effects of novel RAR- and RXR-selective retinoids on myeloid leukemic proliferation and differentiation in vitro.
- Ligand-dependent activation of transcription in vitro by retinoic acid receptor alpha/retinoid X receptor alpha heterodimers that mimics transactivation by retinoids in vivo.
- Differential responses of normal, premalignant, and malignant human bronchial epithelial cells to receptor-selective retinoids.
- Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation.
- Activity of human 11-cis-retinol dehydrogenase (Rdh5) with steroids and retinoids and expression of its mRNA in extra-ocular human tissue.
- Apoptosis induction of POS canine osteosarcoma cells by vitamin D and retinoids.
- Estrogen receptor expression activates the transcriptional and growth-inhibitory response to retinoids without enhanced retinoic acid receptor alpha expression.
- Retinoic acid receptor alpha mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells.
- Overexpressed activated retinoid X receptors can mediate growth inhibitory effects of retinoids in human carcinoma cells.
- Acute promyelocytic leukemia, histone deacetylase, and response to retinoids.
- Inhibition of ribonuclease P activity by retinoids.
- Regulation by retinoids of P2Y2 nucleotide receptor mRNA in human uterine cervical cells.
- Segment-specific pattern of sympathetic preganglionic projections in the chicken embryo spinal cord is altered by retinoids.
- Retinoids are endogenous to the porcine blastocyst and secreted by trophectoderm cells at functionally-active levels.
- Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids.
- Effect of steroid hormones and retinoids on the formation of capillary-like tubular structures of human microvascular endothelial cells in fibrin matrices is related to urokinase expression.
- Three independent lines of evidence suggest retinoids as causal to schizophrenia.
- Retinoids modulate P2U purinergic receptor-mediated changes in transcervical paracellular permeability.
- Expression of retinoic acid receptor-beta sensitizes prostate cancer cells to growth inhibition mediated by combinations of retinoids and a 19-nor hexafluoride vitamin D3 analog.
- Characterization of a region upstream of exon I.1 of the human CYP19 (aromatase) gene that mediates regulation by retinoids in human choriocarcinoma cells.
- Retinoids and their receptors in vertebrate embryogenesis.
- Retinoids augment the bystander effect in vitro and in vivo in herpes simplex virus thymidine kinase/ganciclovir-mediated gene therapy.
- Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family.
- Analysis of esterification of retinoids in the retinal pigmented epithelium of the Mitf-vit (vitiligo) mutant mouse.
- Retinoids regulate tight junctional resistance of cultured human cervical cells.
- Prevention by retinoids of azoxymethane-induced tumors and aberrant crypt foci and their modulation of cell proliferation in the colon of rats.
- Retinoids and alcoholic liver disease.
- Mechanism of the slow induction of apolipoprotein A-I synthesis by retinoids in cynomolgus hepatocytes: involvement of retinoic acid and retinoid X receptors.
- Regulation of the mouse cellular retinoic acid-binding protein-I gene by thyroid hormone and retinoids in transgenic mouse embryos and P19 cells.
- Enhancement of Calu-1 human lung carcinoma cell growth in serum-free medium by retinoids: dependence on AP-1 activation, but not on retinoid response element activation.
- Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells.
- Inhibition of trans-retinoic acid-resistant human breast cancer cell growth by retinoid X receptor-selective retinoids.
- Measurement of retinoids and carotenoids in breast adipose tissue and a comparison of concentrations in breast cancer cases and control subjects.
- Anticoagulant effects of synthetic retinoids mediated via different receptors on human leukemia and umbilical vein endothelial cells.
- Activation of the orphan receptor RIP14 by retinoids.
- Retinoids suppress epidermal growth factor-induced transcription of cyclooxygenase-2 in human oral squamous carcinoma cells.
- Inhibition of cyclin D expression in human breast carcinoma cells by retinoids in vitro.
- Positional apoptosis during vertebrate CNS development in the absence of endogenous retinoids.
- Glucuronidation of retinoids by rat recombinant UDP: glucuronosyltransferase 1.1 (bilirubin UGT).
- Retinoid antagonism of NF-IL6: insight into the mechanism of antiproliferative effects of retinoids in Kaposi's sarcoma.
- Roles of retinoids and their nuclear receptors in the development and prevention of upper aerodigestive tract cancers.
- Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective compounds in mouse thymocytes through a novel apoptosis pathway.
- Stromelysin-3 induction and interstitial collagenase repression by retinoic acid. Therapeutical implication of receptor-selective retinoids dissociating transactivation and AP-1-mediated transrepression.
- Modulation of interferon action by retinoids. Induction of murine STAT1 gene expression by retinoic acid.
- Retinoids suppress phorbol ester-mediated induction of cyclooxygenase-2.
- On the mechanism of isomerization of ocular retinoids by the crayfish Procambarus clarkii.
- Lecithin:retinol acyltransferase and retinyl ester hydrolase activities are differentially regulated by retinoids and have distinct distributions between hepatocyte and nonparenchymal cell fractions of rat liver.
- Suprabasal expression of a dominant-negative RXR alpha mutant in transgenic mouse epidermis impairs regulation of gene transcription and basal keratinocyte proliferation by RAR-selective retinoids.
- Conformational analysis of retinoids and restriction of their dynamics by retinoid-binding proteins.
- Retinoids irreversibly inhibit in vitro growth of Epstein-Barr virus-immortalized B lymphocytes.
- Raloxifene, retinoids, and lavender: "me too" tamoxifen alternatives under study.
- RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids.
- Treatment of axolotls with retinoids for limb regeneration studies.
- Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.
- Retro-retinoids in regulated cell growth and death.
- Retinoids in lung development.
- Vitamin A and retinoids in antiviral responses.
- Retinoids and Hox genes.
- A history of vitamin A and retinoids.
- High-performance liquid chromatography-electrospray mass spectrometry of retinoids.
- Retinoids in cancer chemoprevention.
- Retinoids increase human apolipoprotein A-11 expression through activation of the retinoid X receptor but not the retinoic acid receptor.
- All-trans-retinoic acid 4-hydroxylation in human liver microsomes: in vitro modulation by therapeutic retinoids.
- Growth-inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells.
- Retinoid X receptor-specific retinoids inhibit the ability of retinoic acid receptor-specific retinoids to increase the level of insulin-like growth factor binding protein-3 in human ectocervical epithelial cells.
- Differential regulation of human ectocervical epithelial cell line proliferation and differentiation by retinoid X receptor- and retinoic acid receptor-specific retinoids.
- Potential role for retinoic acid receptor-gamma in the inhibition of breast cancer cells by selective retinoids and interferons.
- Cloning and regulation of cornifin beta, a new member of the cornifin/spr family. Suppression by retinoic acid receptor-selective retinoids.
- Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element.
- Receptor-selective retinoids implicate retinoic acid receptor alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells.
- Differential effects of retinoids and antiestrogens on cell cycle progression and cell cycle regulatory genes in human breast cancer cells.
- Endogenous retinoids in the zebrafish embryo and adult.
- Enhancement of HL-60 differentiation by a new class of retinoids with selective activity on retinoid X receptor.
- Measurement of carotenoids, retinoids, and tocopherols in human lenses.
- Retinoids stimulate fibrinogen production both in vitro (hepatocytes) and in vivo. Induction requires activation of the retinoid X receptor.
- Relation between beta-carotene intake and plasma and adipose tissue concentrations of carotenoids and retinoids.
- Efficient inhibition of activation-induced Fas ligand up-regulation and T cell apoptosis by retinoids requires occupancy of both retinoid X receptors and retinoic acid receptors.
- Visceral heterotaxy syndrome induced by retinoids in mouse embryo.
- Regulation of the induction of ornithine decarboxylase in keratinocytes by retinoids.
- Retinoids downregulate both p60 and p80 forms of tumor necrosis factor receptors in human histiocytic lymphoma U-937 cells.
- Interactions with retinol and retinoids of bovine cellular retinol-binding protein.
- Evidence for the involvement of retinoic acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids.
- Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo.
- Enhanced efficacy of combinations of retinoic acid- and retinoid X receptor-selective retinoids and alpha-interferon in inhibition of cervical carcinoma cell proliferation.
- Modulations of elastin expression and cell proliferation by retinoids in cultured vascular smooth muscle cells.
- Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells.
- Inhibition of nitric oxide synthesis in vascular smooth muscle by retinoids.
- Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
- Retinoids suppress proliferation, induce cell spreading, and up-regulate connexin43 expression only in postconfluent 10T1/2 cells: implications for the role of gap junctional communication.
- Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-alpha acquire sensitivity to growth inhibition by retinoids.
- Correspondence re: S.E. Dew et al., Effects of pharmacological retinoids on several vitamin A-metabolizing enzymes. Cancer Res., 53: 2965-2969, 1993.
- Retinoids and vertebrate development.
- Modulation of collagen synthesis and degradation by retinoids and cytokines in 3T3 L1 preadipocytes.
- Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP).
- Suppression of squamous cell carcinoma growth and differentiation by retinoids.
- Recombinant human retinoic acid receptor beta. Binding of synthetic retinoids and transcriptional activation.
- Carotenoids, tocopherols, and retinoids in human buccal mucosal cells: intra- and interindividual variability and storage stability.
- Retinoids regulate gonadotropin action in cultured rat Sertoli cells.
- Retinoids, breast cancer and NK cells.
- Unfolding of newly made retinol-binding protein by dithiothreitol. Sensitivity to retinoids.
- Retinoids stimulate ApoA-I synthesis by induction of gene transcription in primary hepatocyte cultures from cynomolgus monkey (Macaca fascicularis)
- Retinoids: in vitro interaction with retinol-binding protein and influence on plasma retinol.
- Effects of pharmacological retinoids on several vitamin A-metabolizing enzymes.
- Retinoids increase urokinase-type plasminogen activator production by human retinal pigment epithelial cells in culture.
- The interactions of retinoids with retinol-binding protein. A resonance Raman spectroscopic study.
- Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
- A nonsaponification method for the determination of carotenoids, retinoids, and tocopherols in solid human tissues.
- In vivo biological activity of retinoids partially correlates to their affinity to recombinant retinoic-acid receptor alpha and recombinant-cellular retinoic-acid-binding protein I.
- Cellular metabolism and activation of retinoids: roles of cellular retinoid-binding proteins.
- Endogenous retinoids in rat epididymal tissue and rat and human spermatozoa.
- An everted repeat mediates retinoic acid induction of the gamma F-crystallin gene: evidence of a direct role for retinoids in lens development.
- Cellular retinoic-acid-binding-protein and retinol-binding-protein mRNA expression in the cells of the rat seminiferous tubules and their regulation by retinoids.
- Effects of retinoids on tooth morphogenesis and cytodifferentiations, in vitro.
- Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids.
- Comparative teratogenicity of nine retinoids in the rat.
- Retinoids, retinoid-responsive genes, cell differentiation, and cancer.
- The role of arrestin and retinoids in the regeneration pathway of rhodopsin.
- Retinoids are important cofactors in T cell activation.
- Simultaneous liquid chromatographic determination of carotenoids, retinoids, and tocopherols in human buccal mucosal cells.
- Interactions between retinoids and TGF beta s in mouse morphogenesis.
- Developmental changes in endogenous retinoids during pregnancy and embryogenesis in the mouse.
- Developmental regulation of Sertoli cell aromatase activity and plasminogen activator production by hormones, retinoids and the testicular paracrine factor, PModS.
- Recombinant human retinoic acid receptor alpha. Binding of DNA and synthetic retinoids to the protein expressed in Escherichia coli.
- Effect of retinoids on nuclear retinoic acid receptors mRNA in adipose tissue of retinol-deficient rats.
- Retinoids and retinoid-binding protein expression in rat adipocytes.
- Retinoids and carotenoids in the prevention of oral cancer: a critical appraisal.
- Increased sensitivity of human keratinocytes immortalized by human papillomavirus type 16 DNA to growth control by retinoids.
- The role of retinoids in normal and abnormal embryonic craniofacial morphogenesis.
- Topical and oral retinoids protect Langerhans' cells and epidermal Thy-1+ dendritic cells from being depleted by ultraviolet radiation.
- Retinoids and their receptors in differentiation, embryogenesis, and neoplasia.
- Identification of retinoids with nuclear receptor subtype-selective activities.
- Structure-activity relationships of retinoids as inhibitors of calmodulin-dependent human erythrocyte Ca(2+)-ATPase activity and calmodulin binding to membranes.
- Metabolism of natural retinoids in psoriatic epidermis.
- Multi-stage program of differentiation in human epidermal keratinocytes: regulation by retinoids.
- Effect of retinoids on the release and gene expression of tumor necrosis factor-alpha in human peripheral blood monocytes.
- Immortalization of human keratinocytes by simian virus 40 large T-antigen alters keratin gene response to retinoids.
- Retinoids and butyrate modulate fibroblast growth and contraction of collagen matrices.
- Synthesis of retinoids by human retinal epithelium and transfer to rod outer segments.
- Oral retinoids.
- Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids.
- Anchorage-independent growth of synoviocytes from arthritic and normal joints. Stimulation by exogenous platelet-derived growth factor and inhibition by transforming growth factor-beta and retinoids.
- Visual toxicity of synthetic retinoids.
- Modulation of 3-methylcholanthrene toxicity in cultured neoplastic keratinocytes by glucocorticoids and retinoids is not accounted for by macromolecular adduct formation.
- The actions of retinoids on cellular growth correlate with their actions on gap junctional communication.
- Effect of substratum and retinoids upon the mucosecretory differentiation of airway epithelial cells in vitro.
- The effect of retinoids on dendritic cell function.
- Enhancement of the expression of activation markers on human peripheral blood mononuclear cells by in vitro culture with retinoids and carotenoids.
- Inhibition by retinoids of platelet growth factor-dependent stimulation of DNA synthesis and cell division in density-arrested C3H 10T1/2 fibroblasts.
- Inhibition of Moloney murine lymphoma and sarcoma growth in vivo by dietary retinoids.
- Comparative aspects of carotenoids and retinoids as chemopreventive agents for cancer.
- Effects of retinoids on macrophage function and IL-1 activity.
- Differential effects of retinoids and chronic ethanol consumption on membranes in rats.
- Effects of dietary retinoids upon growth and differentiation of tumors derived from several murine embryonal carcinoma cell lines.
- Effect of retinoids on xenotransplanted human mammary carcinoma cells in athymic mice.
- Influence of retinoids on growth and metastasis of hamster melanoma in athymic mice.
- Distributions of retinoids, retinoid-binding proteins and related parameters in different types of liver cells isolated from young and old rats.
- Inhibition by retinoids of anthralin-induced mouse epidermal ornithine decarboxylase activity and anthralin-promoted skin tumor formation.
- Regulation of human mesothelial cell differentiation: opposing roles of retinoids and epidermal growth factor in the expression of intermediate filament proteins.
- Comparative activity of dietary or topical exposure to three retinoids in the promotion of skin tumor induction in mice.
- Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts.
- Recent advances in clinical use of retinoids.
- Effects of retinoids on metabolizing enzymes and on binding of benzo(a)pyrene to rat tissue DNA.
- Subcellular localization of retinoids, retinoid-binding proteins, and acyl-CoA:retinol acyltransferase in rat liver.
- Retinoids reprogramme pre-bud mesenchyme to give changes in limb pattern.
- Cell surface dynamics of neutrophils stimulated with phorbol esters or retinoids.
- Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization.
- Regulation of accessory cell function by retinoids in murine immune responses.
- Studies on the in vivo transfer of retinoids from parenchymal to stellate cells in rat liver.
- In-vitro teratogenicity of retinoids.
- Isomerization of all-trans-retinoids to 11-cis-retinoids in vitro.
- Induction of tissue transglutaminase in human peripheral blood monocytes by intracellular delivery of retinoids.
- Inhibition of conjunctival transdifferentiation by topical retinoids.
- Detection of radical species in mixtures of some retinoids with hematin by using the ESR spin-trapping technique.
- Synthesis of mucous glycoproteins by rabbit tracheal cells in vitro. Modulation by substratum, retinoids and cyclic AMP.
- Characterization of transglutaminase activity in rabbit tracheal epithelial cells. Regulation by retinoids.
- Accumulation of cholesterol 3-sulfate during in vitro squamous differentiation of rabbit tracheal epithelial cells and its regulation by retinoids.
- Retinoic acid-binding protein in the chick limb bud: identification at developmental stages and binding affinities of various retinoids.
- Retinoids. Structure-function relationship in normal and leukemic hematopoiesis in vitro.
- Correlation between the induction of leukemic cell differentiation by various retinoids and modulation of protein kinases.
- The effects of two retinoids on limb regeneration in Pleurodeles waltl and Triturus vulgaris.
- Hepatic retinol metabolism. Distribution of retinoids, enzymes, and binding proteins in isolated rat liver cells.
- Retinoids, retinoid-binding proteins, and retinyl palmitate hydrolase distributions in different types of rat liver cells.
- Effect of retinoids on the growth, ultrastructure, and cytoskeletal structures of malignant rat osteoblasts.
- Computer-assisted correlation of structure and biological activity in a set of retinoids.
- Metabolism of retinoids by embryonal carcinoma cells.
- Human T-cell leukemia virus I induction by 5-iodo-2'-deoxyuridine and N-methyl-N'-nitro-N-nitrosoguanidine: inhibition by retinoids, L-ascorbic acid, and DL-alpha-tocopherol.
- Synthetic retinoids in dermatology.
- Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures.
- Comparative study of blocking effects of various retinoids on the occurrence of permanent proliferation of vaginal epithelium in mice treated neonatally with estrogen.
- Retinoids and pattern formation in a hydroid.
- Retinoid feeding, hormone inhibition, and/or immune stimulation and the progression of N-methyl-N-nitrosourea-induced rat mammary carcinoma: suppression by retinoids of peptide hormone-induced tumor cell proliferation in vivo and in vitro.
- Relationship between binding affinities to cellular retinoic acid-binding protein and biological potency of a new series of retinoids.
- Regulation of epidermal transglutaminase activity and terminal differentiation by retinoids and phorbol esters.
- Induction of ornithine decarboxylase activity and DNA synthesis in hairless mouse epidermis by retinoids.
- Effects of four retinoids in N-nitrosobis(2-oxopropyl)amine-treated hamsters.
- Divergent effects of retinoids on pancreatic and liver carcinogenesis in azaserine-treated rats.
- Role of retinoids in differentiation and carcinogenesis.
- Retinoids induce differentiation of type A spermatogonia in vitro: organ culture of mouse cryptorchid testes.
- Inhibition of carcinogenesis by retinoids.
- Action of epidermal growth factor and retinoids on anchorage-dependent and -independent growth of nontransformed rat kidney cells.
- Action of retinoids on the anchorage-independent growth of normal rat kidney fibroblasts induced by 12-O-tetradecanoylphorbol-13-acetate or sarcoma growth factor.
- Nomenclature of retinoids. Recommendations 1981.
- Utilization of retinoids in the bullfrog retina.
- Variable effects of retinoids on two pigmenting human melanoma cell lines.
- Identification of the endogenous retinoids associated with three cellular retinoid-binding proteins from bovine retina and retinal pigment epithelium.
- Retinoids and phorbol esters alter release of fibronectin from enucleated cells.
- Secretion of testicular transferrin by cultured Sertoli cells is regulated by hormones and retinoids.
- Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.
- Inhibition of pancreatic carcinogenesis by retinoids in azaserine-treated rats.
- Photochemical destruction of the virucidal activities of retinoids and unsaturated fatty acids.
- Retinoids in experimental diets.
- Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin.
- N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BL/6 X DBA/2 F1 mice as a useful model for study of chemoprevention of cancer with retinoids.
- Modification of sister chromatid exchanges and radiation-induced transformation in rodent cells by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and two retinoids.
- Anti-cancer action of retinoids.
- Dermatology-epitomes of progress: update on the use of retinoids.
- Effects of retinoids on normal and neoplastic human cells cultured in vitro.
- Structure-activity relationships of retinoids in hamster tracheal organ culture.
- Structure-activity relationships among various retinoids and their ability to inhibit neoplastic transformation and to increase cell adhesion in the C3H/10T1/2 CL8 cell line.
- Stimulation of melanogenesis in a human melanoma cell line by retinoids.
- Retinoids as regulators of macrophage function.
- Characterization of the effects of different retinoids on the growth and differentiation of a human melanoma cell line and selected subclones.
- Mechanism of virucidal activity of retinoids: protein removal from bacteriophage phi 6 envelope.
- Inhibition of carcinogenesis by retinoids.
- Binding of retinoids to human breast cancer cell lines and their effects on cell growth.
- Effects of retinoids on induction of differentiation of cultured mouse myeloid leukemia cells.
- Relationship between binding affinities to cellular retinoic acid-binding protein and in vivo and in vitro properties for 18 retinoids.
- Inhibition of human melanoma colony formation by retinoids.
- Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H/10T1/2 clone 8 cells.
- Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
- Assay of retinoids in biological samples by reverse-phase high-pressure liquid chromatography.
- Determination of binding affinities of retinoids to retinoic acid-binding protein and serum albumin.
- Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids).
- Separation of the natural retinoids by high-pressure liquid chromatography.
- Chemical synthesis of phosphorylated retinoids. Their mannosyl acceptor activity in rat liver membranes.
- Toxicity of anti-carcinogenic retinoids in organ culture.
- Effect of aromatic retinoids on rat chondrosarcoma glycosaminoglycan biosynthesis.
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