Korsakoff's syndrome

Korsakoff's syndrome (also called Korsakoff's dementia, Korsakoff's psychosis, or amnesic-confabulatory syndrome) is a neurological disorder caused by a lack of thiamine (vitamin B1) in the brain. Its onset is linked to chronic alcohol abuse and/or severe malnutrition.

Korsakoff’s psychosis
Julia Kofler, M.D.
http://neuro.pathology.pitt.edu

Drug Abuse II: Alcohol
http://www.epcc.edu/

Warnicke-Korsikof Syndrome
http://faculty.mccneb.edu

Alcoholic Dementia
http://www.sjsu.edu/

Care of the Chemically Impaired
http://www.lahc.edu/

Substance Abuse Use, Abuse and Dependence
http://online.santarosa.edu

Assessment and Treatment of Addictive Behaviors
Carl W. Lejuez, PhD
http://www.addiction.umd.edu

Neurotoxic Effects of Solvents
William Boyes
http://www.unc.edu/courses/2006
http://www.unc.edu/courses/2007

Medical Emergencies Neurology
http://web.uaccb.edu/

Korsakoff’s Psychosis: a diencephalic disorder
http://www.clas.wayne.edu

Substance-related Disorders
http://www.mccc.edu

Alcohol and Alcoholism
http://www.med.und.edu/

Psycho-Addictive Disorders
Elisa A. Mancuso
http://www2.sunysuffolk.edu/

Korsakoff’s Psychosis - amnesia
http://hercules.gcsu.edu/


60 Published articles on Korsakoff's syndrome
1.       Thomson AD, Marshall EJ. The natural history and pathophysiology of Wernicke's; Encephalopathy and Korsakoff's Psychosis. Alcohol Alcohol. 2006; Mar-Apr;41(2):151-8. Epub 2005 Dec 29.
2.       Casadevall-Codina T, Pascual-Millán LF, Fernández-Turrado T, Escalza-Cortina; I, Navas-Vinagre I, Fanlo-Meroño C, Morales-Asín F. [Pharmacological treatment of; Korsakoff's psychosis. a review of the literature and experience in two cases].; Rev Neurol. 2002 Aug 16-31;35(4):341-5. Review. Spanish.
3.       Smith ID, Flanigan C. Korsakoff's psychosis in Scotland. evidence for; increased prevalence and regional variation. Alcohol Alcohol Suppl. 2000; May-Jun;35(1):8-10.
4.       Oda Y, Shindoh M, Yukioka H, Iimuro S, Nishi S, Asada A, Nagata T. A case of; crush syndrome occurring during alcohol withdrawal. extended disturbance of; consciousness with development of persistent Korsakoff's psychosis. Intensive; Care Med. 1998 Nov;24(11):1231.
5.       Smith ID, Flanigan C. Parenteral thiamine and Korsakoff's psychosis. Alcohol; Alcohol. 1998 Sep-Oct;33(5):549-51.
6.       Ramayya A, Jauhar P. Increasing incidence of Korsakoff's psychosis in the east; end of Glasgow. Alcohol Alcohol. 1997 May-Jun;32(3):281-5.
7.       Moffoot A, O'Carroll RE, Murray C, Dougall N, Ebmeier K, Goodwin GM. Clonidine; infusion increases uptake of 99mTc-Exametazime in anterior cingulate cortex in; Korsakoff's psychosis. Psychol Med. 1994 Feb;24(1):53-61.
8.       Halliday G, Ellis J, Heard R, Caine D, Harper C. Brainstem serotonergic; neurons in chronic alcoholics with and without the memory impairment of; Korsakoff's psychosis. J Neuropathol Exp Neurol. 1993 Nov;52(6):567-79. PubMed; PMID. 8229075.
9.       Halliday G, Ellis J, Harper C. The locus coeruleus and memory. a study of; chronic alcoholics with and without the memory impairment of Korsakoff's; psychosis. Brain Res. 1992 Dec 11;598(1-2):33-7.
10.   Effects of Clonidine On Cognition and rCbf in Korsakoff's Psychosis. Moffoot ; A, O'Carroll R, Ebmeier KP, Goodwin GM. MRC Brain Metabolism Unit, Royal; Edinburgh Hospital, Morningside Park, Edinburgh, EH10 5HF, UK. J Psychopharmacol.; 1992 Jan;6(1):109.
11.   Deary IJ, Hunter R, Langan SJ, Goodwin GM. Inspection time, psychometric; intelligence and clinical estimates of cognitive ability in pre-senile; Alzheimer's disease and Korsakoff's psychosis. Brain. 1991 Dec;114 ( Pt; 6):2543-54.
12.   Bond NW, Homewood J. Wernicke's encephalopathy and Korsakoff's psychosis. to ; fortify or not to fortify? Neurotoxicol Teratol. 1991 Jul-Aug;13(4):353-5. PubMed; PMID. 1921914.
13.   Ron MA, Feinstein A. Korsakoff's psychosis in the presence of multiple; sclerosis. an unusual cognitive state. J Neurol Neurosurg Psychiatry. 1990; Jul;53(7):625.
14.   Kapur N. Korsakoff's psychosis. J Neurol Neurosurg Psychiatry. 1990; Mar;53(3):270.
15.   Besson JA, Crawford JR, Parker DM, Smith FW. Magnetic resonance imaging in; Alzheimer's disease, multi-infarct dementia, alcoholic dementia and Korsakoff's; psychosis. Acta Psychiatr Scand. 1989 Nov;80(5):451-8.
16.   Hunter R, McLuskie R, Wyper D, Patterson J, Christie JE, Brooks DN, McCulloch; J, Fink G, Goodwin GM. The pattern of function-related regional cerebral blood; flow investigated by single photon emission tomography with 99mTc-HMPAO in; patients with presenile Alzheimer's disease and Korsakoff's psychosis. Psychol; Med. 1989 Nov;19(4):847-55.
17.   Hunter R, Merrick MV, Ferrington C, Notghi A, McLuskie R, Christie JE,; Goodwin GM. Cerebral vascular transit time in Alzheimer's disease and Korsakoff's; psychosis and its relation to cognitive function. Br J Psychiatry. 1989; Jun;154:790-6.
18.   Feinstein A, Ron M. Korsakoff's psychosis in the presence of multiple; sclerosis. an unusual cognitive state. J Neurol Neurosurg Psychiatry. 1989; Apr;52(4):540-1.
19.   Neciga EG, Peralta AG, Polaina M, Sureda B, Bautista J. Cyst of the septum; pellucidum and Korsakoff's psychosis. Eur Neurol. 1989;29(2):99-101.
20.   Farr RW, Blankenship DC, Viti A, Albrink MJ. Korsakoff's psychosis due to; massive beer intake provoked by diabetes insipidus. South Med J. 1988; May;81(5):677-8.
21.   Mair RG, Langlais PJ, Mazurek MF, Beal MF, Martin JB, McEntee WJ. Reduced; concentrations of arginine vasopressin and MHPG in lumbar CSF of patients with; Korsakoff's psychosis. Life Sci. 1986 Jun 23;38(25):2301-6.
22.   Martin PR, Loewenstein RJ, Kaye WH, Ebert MH, Weingartner H, Gillin JC. Sleep; EEG in Korsakoff's psychosis and Alzheimer's disease. Neurology. 1986; Mar;36(3):411-4.
23.   Mair RG, McEntee WJ. Cognitive enhancement in Korsakoff's psychosis by; clonidine. a comparison with L-dopa and ephedrine. Psychopharmacology (Berl).; 1986;88(3):374-80.
24.   Mair RG, Doty RL, Kelly KM, Wilson CS, Langlais PJ, McEntee WJ, Vollmecke TA.; Multimodal sensory discrimination deficits in Korsakoff's psychosis.; Neuropsychologia. 1986;24(6):831-9.
25.   Martin PR, Higa S, Burns RS, Tamarkin L, Ebert MH, Markey SP. Decreased; 6-hydroxymelatonin excretion in Korsakoff's psychosis. Neurology. 1984; Jul;34(7):966-8.
26.   McEntee WJ, Mair RG, Langlais PJ. Neurochemical pathology in Korsakoff's; psychosis. implications for other cognitive disorders. Neurology. 1984; May;34(5):648-52.
27.   Martin PR, Weingartner H, Gordon EK, Burns RS, Linnoila M, Kopin IJ, Ebert; MH. Central nervous system catecholamine metabolism in Korsakoff's psychosis. Ann; Neurol. 1984 Feb;15(2):184-7.
28.   Yudofsky SC, Stevens L, Silver J, Barsa J, Williams D. Propranolol in the; treatment of rage and violent behavior associated with Korsakoff's psychosis. Am ; J Psychiatry. 1984 Jan;141(1):114-5.
29.   Harbinson HJ. Alcoholic Korsakoff's psychosis. a psychometric,; neuroradiological and neurophysiological investigation of nine cases. Ulster Med ; J. 1984;53(2):103-10.
30.   Mair RG, McEntee WJ. Korsakoff's psychosis. noradrenergic systems and; cognitive impairment. Behav Brain Res. 1983 Jul;9(1):1-32. Review.
31.   Budassi SA. Wernicke's encephalopathy and Korsakoff's psychosis. J Emerg; Nurs. 1982 Nov-Dec;8(6):295-7.
32.   Devgun MS, Fiabane A, Paterson CR, Zarembski P, Guthrie A. Vitamin and; mineral nutrition in chronic alcoholics including patients with Korsakoff's; psychosis. Br J Nutr. 1981 May;45(3):469-73.
33.   Mair R, Capra C, McEntee WJ, Engen T. Odor discrimination and memory in; Korsakoff's psychosis. J Exp Psychol Hum Percept Perform. 1980 Aug;6(3):445-58.;
34.   McEntee WJ, Mair RG. Memory enhancement in Korsakoff's psychosis by; clonidine. further evidence for a noradrenergic deficit. Ann Neurol. 1980; May;7(5):466-70.
35.   Mair WG, Warrington EK, Weiskrantz L. Memory disorder in Korsakoff's; psychosis. a neuropathological and neuropsychological investigation of two cases.; Brain. 1979 Dec;102(4):749-83.
36.   Seidel HA, Hodgkinson PE. Behaviour modification and long-term learning in; Korsakoff's psychosis. Nurs Times. 1979 Oct 25;75(43):1855-7.
37.   Berglund M, Gustafson L, Hagberg B. Amnestic-confabulatory syndrome in; hydrocephalic dementia and Korsakoff's psychosis in alcoholism. Acta Psychiatr; Scand. 1979 Oct;60(4):323-33.
38.   Breen KJ, Wood B. The prevention of Korsakoff's psychosis. Med J Aust. 1979; Jun 16;1(12):570-2.
39.   Price J, Theodoros MT. The prevention of Korsakoff's psychosis. Med J Aust.; 1979 Apr 7;1(7):285.
40.   McEntee WJ, Mair RG. Memory impairment in Korsakoff's psychosis. a; correlation with brain noradrenergic activity. Science. 1978 Nov; 24;202(4370):905-7.
41.   McEntee MJ, Mair RG. Central monoamine activity in Korsakoff's psychosis.; Trans Am Neurol Assoc. 1978;103:233-5.
42.   Kapur N, Butters N. Visuoperceptive deficits in long-term alcoholics and; alcoholics with Korsakoff's psychosis. J Stud Alcohol. 1977 Nov;38(11):2025-35.;
43.   Sattler L. Confabulation in Korsakoff's psychosis. Comment on the report by; Keller and Efron. J Stud Alcohol. 1976 Jul;37(7):1010-3.
44.   Berglund M, Ingvar DH. Cerebral blood flow and its regional distribution in; alcoholism and in Korsakoff's psychosis. J Stud Alcohol. 1976 May;37(5):586-97.;
45.   Jaffe PG, Katz AN. Attenuating anterograde amnesia in Korsakoff's psychosis. ; J Abnorm Psychol. 1975 Oct;84(5):559-62.
46.   Murray DJ, Hitchcock CH. The nature of the memory deficit in Korsakoff's; psychosis. Can J Psychol. 1973 Dec;27(4):414-21.
47.   Caird WK, Inglis J, Laverty SG. Sedation threshold in Korsakoff's psychosis. ; Int J Neuropsychiatry. 1966 Apr;2(2):188-92.
48.   RATHOD NH. KORSAKOFF'S PSYCHOSIS. Nurs Times. 1965 Jan 22;61:116-8. PubMed; PMID. 14253685.
49.   TALLAND GA. Psychological studies of Korsakoff's psychosis. VI. Memory and; learning. J Nerv Ment Dis. 1960 May;130:366-85.
50.   VAN REETH PC, SOURIS M. [The electroencephalogram in Korsakoff's psychosis of; alcoholic origin]. Acta Neurol Belg. 1960 Mar;60:302-11. French.
51.   TALLAND GA. Psychological studies of Korsakoff's psychosis. V. Spontaneity; and activity rate. J Nerv Ment Dis. 1960 Jan;130:16-25.
52.   TALLAND GA, EKDAHL M. Psychological studies of Korsakoff's psychosis. IV. The; rate and mode of forgetting narrative material. J Nerv Ment Dis. 1959; Oct;129:391-404.
53.   VICTOR M, TALLAND GA, ADAMS RD. Psychological studies of Korsakoff's; psychosis. I. General intellectual functions. J Nerv Ment Dis. 1959; Jun;128(6):528-37.
54.   TALLAND GA. Psychological studies of Korsakoff's psychosis. III. Concept; formation. J Nerv Ment Dis. 1959 Mar;128(3):214-26.
55.   TALLAND GA, MILLER A. Perceptual sets in Korsakoff's psychosis. J Abnorm; Psychol. 1959 Mar;58(2):234-40.
56.   TALLAND GA. Psychological studies of Korsakoff's psychosis. II. Perceptual; functions. J Nerv Ment Dis. 1958 Sep;127(3):197-219.
57.   TOMMASI M. [Axial degeneration of the corpus callosum (Marchiafava-Bignami's ; syndrome) in a case of Korsakoff's psychosis; anatomo-clinical case report]. J; Med Lyon. 1957 Apr 5;38(894):289-97. French.
58.   58. SPROFKIN BE, SCIARRA D. Korsakoff's psychosis associated with cerebral; tumors. Neurology. 1952 Sep-Oct;2(5):427-34.
59.   SPROFKIN BE, SCIARRA D. Korsakoff's psychosis associated with cerebral; tumors. Trans Am Neurol Assoc. 1951;56:98-101.
60.   Cubitt AW. SPONTANEOUS SUBARACHNOID HAEMORRHAGE, WITH KORSAKOFF'S PSYCHOSIS. ; Br Med J. 1930 Aug 9;2(3631):212-3.