Normal Newborn Care - Advances in Maternal and Neonatal Health
Normal Newborn Care 
Session Objective 
    * Define essential elements of early newborn care
    * Discuss best practices and technologies for promoting newborn health
    * Use relevant data and information to develop appropriate essential newborn recommendations
Newborn Deaths 
Essential Newborn Care Interventions 
    * Clean childbirth and cord care
          o Prevent newborn infection
    * Thermal protection
          o Prevent and manage newborn hypo/hyperthermia
    * Early and exclusive breastfeeding
          o Started within 1 hour after childbirth
    * Initiation of breathing and resuscitation
          o Early asphyxia identification and management
    * Eye care
          o Prevent and manage ophthalmia neonatorum
    * Immunization
          o At birth: bacille Calmette-Guerin (BCG) vaccine, oral poliovirus vaccine (OPV) and hepatitis B virus (HBV) vaccine (WHO)
    * Identification and management of sick newborn
    * Care of preterm and/or low birth weight newborn
Cleanliness to Prevent Infection 
    * Principles of cleanliness essential in both home and health facilities childbirths
    * Principles of cleanliness at childbirth
          o Clean hands
          o Clean perineum
          o Nothing unclean introduced vaginally
          o Clean delivery surface
          o Cleanliness in cord clamping and cutting
          o Cleanliness for cord care
    * Infection prevention/control measures at healthcare facilities
Thermal Protection 
    * Newborn physiology
          o Normal temperature: 36.5–37.5°C
          o Hypothermia: < 36.5°C
          o Stabilization period: 1st 6–12 hours after birth
                + Large surface area
                + Poor thermal insulation
                + Small body mass to produce and conserve heat
                + Inability to change posture or adjust clothing to respond to thermal stress
    * Increase hypothermia
          o Newborn left wet while waiting for delivery of placenta
          o Early bathing of newborn (within 24 hours)
Hypothermia Prevention 
    * Deliver in a warm room
    * Dry newborn thoroughly and wrap in dry, warm cloth
    * Keep out of draft and place on a warm surface
    * Give to mother as soon as possible
          o Skin-to-skin contact first few hours after childbirth
          o Promotes bonding
          o Enables early breastfeeding
    * Check warmth by feeling newborn’s feet every 15 minutes
    * Bathe when temperature is stable (after 24 hours)
Early and Exclusive Breastfeeding 
    * Early contact between mother and newborn
          o Enables breastfeeding
          o Rooming-in policies in health facilities prevents nosocomial infection
    * Best practices
          o No prelacteal feeds or other supplement
          o Giving first breastfeed within one hour of birth
          o Correct positioning to enable good attachment of the newborn
          o Breastfeeding on demand
          o Psycho-social support to breastfeeding mother
Breathing Initiation and Resuscitation 
    * Spontaneous breathing (> 30 breaths/min.) in most newborns
          o Gentle stimulation, if at all
    * Effectiveness of routine oro-nasal suctioning is unknown
          o Biologically plausible advantages – clear airway
          o Potentially real disadvantages – cardiac arrhythmia
          o Bulb suctioning preferred
    * Newborn resuscitation may be needed
          o Fetal distress
          o Thick meconium staining
          o Vaginal breech deliveries
          o Preterm
Eye Care To Prevent or Manage Ophthalmia Neonatorum 
    * Ophthalmia neonatorum
          o Conjunctivitis with discharge during first 2 weeks of life
          o Appears usually 2–5 days after birth
          o Corneal damage if untreated
          o Systemic progression if not managed
    * Etiology
          o N. gonorrhea
                + More severe and rapid development of complications
                + 30–50% mother-newborn transmission rate
          o C. trachomatis
Eye Care To Prevent or Manage Ophthalmia Neonatorum (continued) 
    * Prophylaxis
          o Clean eyes immediately
          o 1% Silver nitrate solution
                + Not effective for chlamydia
          o 2.5% Povidone-iodine solution
          o 1% Tetracycline ointment
                + Not effective vs. some N. gonorrhea strains
    * Common causes of prophylaxis failure  
          o Giving prophylaxis after first hour
          o Flushing of eyes after silver nitrate application
          o Using old prophylactic solutions
Efficacy of Prophylaxis for Conjunctivitis in China 
    * Objective: To assess etiology of newborn conjunctivitis and evaluate the efficacy of regimens in China
    * Design: November 1989 to October 1991 rotated regimens monthly: tetracycline, erythromycin, silver nitrate
    * 302 (6.7%) infants developed conjunctivitis, most S. aureus (26.2%) and chlamydia (22.5%)
    * Silver nitrate, tetracycline: fewer cases than no prophylaxis (p < 0.05), erythromycin: not significant
Prophylaxis for Conjunctivitis: Objective and Design 
    * Objective: To compare efficacy in prevention of nongonococcal conjunctivitis
    * Design: Randomized control trial to compare erythromycin, silver nitrate, no prophylaxis
          o Examined with test for leukocyte esterase and chlamydia trachomatis antibody probe 30–48 hours postpartum, 13–15 days later, and telephone contact up to 60 days of life
    * Main outcome measured: conjunctivitis within 60 days of life and nasolacrimal duct patency
Prophylaxis for Conjunctivitis:  Results and Conclusion 
    * Results: 630 infants
    * 109 with conjunctivitis
          o Silver nitrate vs. no prophylaxis: Hazard ratio 0.61 (0.39-0.97)
                + Chemical conjunctivitis with silver nitrate resolves within 48 hours
          o Erythromycin vs. no prophylaxis: Hazard ratio 0.69 (not significant)
    * Conclusion: Parental choice of prophylaxis, including no prophylaxis, is reasonable IF antenatal care and STD screening
Povidone-Iodine for Conjunctivitis:  Objective and Design 
    * Objective: To determine incidence and type of conjunctivitis after povidone-iodine in Kenya
    * Design: Rotate regimen weekly: erythromycin, silver nitrate, povidone iodine
    * Results:
          o Conjunctivitis:
                + Chlamydia in 50.5%
                + S. aureus in 39.7%
          o More infections in silver nitrate than povidone-iodine, OR 1.76, p < 0.001
          o More infections in erythromycin OR 1.38, p=0.001
Povidone-Iodine for Conjunctivitis: Conclusion 
Povidone-iodine:
          o Is good prophylaxis
          o Has wider antibacterial spectrum
          o Causes greater reduction in colony-forming units and number of bacterial species
          o Is active against viruses
          o Is inexpensive
Immunization 
    * BCG vaccinations in all population at high risk of tuberculosis infection
    * Single dose of OPV at birth or in the two weeks after birth
    * HBV vaccination as soon as possible where perinatal infections are common
Summary 
The essential components of normal newborn care include:
    * Clean delivery and cord care
    * Thermal protection
    * Early and exclusive breastfeeding
    * Monitoring
    * Eye care
    * Immunization
References 
Normal Newborn Care.ppt
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