Retinopathy of Prematurity

Retinopathy of Prematurity
Medical and Surgical Update
Presentation by: Tim Stout MD PhD
Casey Eye Institute
Oregon Health Sciences University

Retinopathy of Prematurity - What is it?

An uncontrolled neovascular process in which retinal endothelial cells stop developing and die, then later, proliferate, migrate, organize, scar and cause a detachment of the retina

ROP - What is it ?

* Found in premature infants with immature retinal vasculature who have received supplemental oxygen.
* It is the most common cause of permanent blindness in children
o it lasts a lifetime
o it shares common pathophysiologic features with a variety of common diseases


Normal Human Eye
Normal Human Retina
ROP – Geography (Zones)
TEMPORAL
NASAL
SUPERIOR
INFERIOR, RIGHT EYE
ROP Classification

* Stage 1 : Line separates vascular and avascular retina
* Stage 2 : Ridge (intra-retinal neovascularization)
* Stage 3 : Extra-retinal neovascularization
* Stage 4 : Subtotal retinal detachment
* Stage 5 : Total retinal detachment

PLUS Disease - dilated and tortuous retinal vessels
ROP Classification
THRESHOLD DISEASE
ROP Progression
ROP Incidence - Gestational Age
ROP Incidence - Birth Weight
ROP Screening - When
ROP - Current Treatment
Surgical Treatment
ROP - Laser Technique
Laser Treatment for ROP
ROP - Scleral Buckle
ROP - Late Sequelae
ROP - Retinal Dragging

ROP is a BIOLOGIC process which we currently treat MECHANICALLY

Retinopathy of Prematurity.ppt