Odontogenic Cysts and Tumors
Odontogenic Cysts and Tumors 
Presentation lecture by:Michael Underbrink, MD
Anna Pou, MD
Introduction 
    * Variety of cysts and tumors
    * Uniquely derived from tissues of developing teeth
    * May present to otolaryngologist
Odontogenesis 
    * Projections of dental lamina into ectomesenchyme
    * Layered cap (inner/outer enamel epithelium, stratum intermedium, stellate reticulum)
    * Odontoblasts secrete dentin   ameloblasts (from IEE)   enamel
    * Cementoblasts   cementum
    * Fibroblasts   periodontal  membrane
Diagnosis 
    * Complete history
          o Pain, loose teeth, occlusion, swellings, dysthesias, delayed tooth eruption
    * Thorough physical examination
          o Inspection, palpation, percussion, auscultation
    * Plain radiographs
          o Panorex, dental radiographs
    * CT for larger, aggressive lesions
Diagnosis 
    * Differential diagnosis
    * Obtain tissue
          o FNA – r/o vascular lesions, inflammatory
          o Excisional biopsy – smaller cysts, unilocular tumors
          o Incisional biopsy – larger lesions prior to definitive therapy
Odontogenic Cysts 
    * Inflammatory
          o Radicular
          o Paradental
    * Developmental
          o Dentigerous
          o Developmental lateral periodontal
          o Odontogenic keratocyst
          o Glandular odontogenic
Radicular (Periapical) Cyst 
    * Most common (65%)
    * Epithelial cell rests of Malassez
    * Response to inflammation
    * Radiographic findings
          o Pulpless, nonvital tooth
          o Small well-defined periapical radiolucency
    * Histology
    * Treatment – extraction, root canal
Radicular Cyst
Residual Cyst
Paradental Cyst 
    * Associated with partially impacted 3rd molars
    * Result of inflammation of the gingiva over an erupting molar
    * 0.5 to 4% of cysts
    * Radiology – radiolucency in apical portion of the root
    * Treatment – enucleation
Dentigerous (follicular) Cyst 
    * Most common developmental cyst (24%)
    * Fluid between reduced enamel epithelium and tooth crown
    * Radiographic findings
          o Unilocular radiolucency with well-defined sclerotic margins
    * Histology
          o Nonkeratinizing squamous epithelium
    * Treatment – enucleation, decompression
Dentigerous Cyst
Developmental Lateral Periodontal Cyst 
Odontogenic Keratocyst 
Treatment of OKC 
Glandular Odontogenic Cyst 
Treatment of GOC 
Nonodontogenic Cysts 
Incisive Canal Cyst 
Stafne Bone Cyst 
Traumatic Bone Cyst 
Surgical Ciliated Cyst 
Odontogenic Tumors 
Ameloblastoma 
Treatment of Ameloblastoma 
Calcifying Epithelial Odontogenic Tumor 
Treatment of CEOT 
Adenomatoid Odontogenic Tumor 
Squamous Odontogenic Tumor 
Calcifying Odontogenic Cyst 
Mesenchymal Odontogenic Tumors 
Odontogenic Myxoma 
Cementoblastoma 
Mixed Odontogenic Tumors 
Related Jaw Lesions 
Central Giant Cell Granuloma 
Brown Tumor 
Aneurysmal Bone Cyst 
Fibrous Dysplasia 
Ossifying Fibroma 
Condensing Osteitis 
Conclusion
Case Presentation 
Physical Examination
Radiographs 
Pathology
Treatment
Odontogenic Cysts and Tumors.ppt

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