21 April 2009

Bioactive Lipids: Membrane Sphingolipids And Gangliosides



Bioactive Lipids: Membrane Sphingolipids And Gangliosides
Powerpoint presentation by:Michael A. Collins, Ph.D.

Four major phospholipids in mammalian cell membranes
Structure of a ceramide (N-acylsphingosine)
Structure of sphingomyelin
Sphingosine

SPHINGOMYELIN-CERAMIDE-SPHINGOSINE BIOCHEMISTRY

Model of dynamics of membrane raft constituents and organization
Membrane raft-containing neutral and acid sphingomyelinases (SMase) activation and regulation in signal transduction
sphingomyelin
cerebrosides
and sulfatide(s)
Sphingolipidoses are lysosomal storage diseases with inherited defects in sphingolipid (SL) catabolism
Key points:
Structures of common sphingolipids
Sphingolipidoses are lysosomal storage diseases with inherited defects in sphingolipid (SL) catabolism: GANGLIOSIDOSES

Sphingolipids.ppt

at Tuesday, April 21, 2009
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